Can I take Alcohol and Norco together?
Drug interaction guide
Originally published 12 May 2026
Meets Patient’s editorial guidelines
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Combining alcohol with Norco (hydrocodone and paracetamol) is extremely dangerous. It can lead to severe drowsiness, slowed or stopped breathing, coma, and even death. Additionally, both alcohol and the paracetamol in Norco can damage the liver; taking them together significantly increases the risk of acute liver failure.
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Why this happens
Both alcohol and hydrocodone (the opioid in Norco) are central nervous system depressants, meaning they slow down brain activity and the signals that tell your body to breathe. When taken together, these effects are multiplied (synergistic). Furthermore, alcohol changes how the liver processes paracetamol, leading to the buildup of toxic substances that destroy liver cells.
What you should do
Back to contentsDo not drink any alcohol while taking Norco. If you have accidentally combined them and feel excessively sleepy, dizzy, or have difficulty breathing, seek emergency medical help immediately. Always inform your doctor if you have a history of heavy alcohol use before starting this medication.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
12 May 2026 | Originally published

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