Patientforskning
Logga in
Alla studier
RekryteringNAINTERVENTIONELL

Motor Slowing and Its Lesion-related Correlates in Alzheimer's Disease

This study aims to understand how Alzheimer's disease can slow down a person's thinking and reaction times. The researchers want to see if these changes are linked to specific areas of the brain affected by the disease. They will use brain scans (MRI), detailed memory and thinking tests (neuropsychological evaluation), and blood samples to gather information. The goal is to better understand how Alzheimer's impacts our ability to focus and react, which could help in developing better ways to diagnose and support people living with the condition.

Överblick

Status
Rekrytering
Fas
NA
Sponsor
Centre Hospitalier Universitaire, Amiens
Inskrivningsmål
155
Starta
16 Dec 2015
Beräknad slutförande
16 Dec 2028
Alzheimer Disease

Vad handlar denna studie om?

This research study is titled "Motor Slowing and Its Lesion-related Correlates in Alzheimer's Disease." In simpler terms, it's about understanding why people with Alzheimer's disease sometimes find their movements and thoughts becoming slower, and how this links to different parts of their brain. The researchers are particularly interested in how attention problems, which can make you react more slowly, are connected to what they see on brain scans.

Alzheimer's disease is a complex condition, and one of the ways it affects people is by changing their ability to pay attention and think quickly. This study wants to get a clearer picture of these changes. By using advanced brain scans, specially designed memory and thinking tests, and blood tests, the team hopes to find out more about which specific brain changes might be causing the slowing down of thoughts and reactions.

Understanding these connections better is important. It could help doctors to identify Alzheimer's disease earlier, create more personalised care plans, and even guide the development of new treatments in the future. The more we know about how Alzheimer's affects the brain, the better equipped we are to support those living with the condition.

Viktiga punkter

  • The study aims to understand how Alzheimer's affects thinking speed and links to brain changes.
  • It involves brain scans (MRI), memory tests, and blood tests.
  • Participants must be aged 40-85, speak French, and be patients at a specific memory clinic.
  • Friska frivilliga behövs också för jämförelse.
  • Du kan dra dig ur studien när som helst.
  • No new medications are given as part of this study.

Vem kan vara berättigad?

This study is looking for people aged between 40 and 85 years old. Participants should speak French as their first language and be patients at the Amiens Memory Resource and Research Centre (CMRR). They are looking for people diagnosed with mild cognitive impairment (MCI) or mild dementia due to Alzheimer's, Lewy Body Disease (LBD), or Frontotemporal Lobar Degeneration (FTLD). They also need healthy volunteers of a similar age and gender to compare with the patients.

There are also some reasons why someone might not be able to join. For example, if you have severe reading or writing difficulties, or certain serious medical conditions like uncontrolled thyroid problems, serious heart failure, severe breathing problems, or advanced cancer. Past or present alcohol abuse would also make someone unsuitable. If you have other serious brain conditions like a history of stroke, epilepsy requiring ongoing treatment, or certain mental health conditions (other than treated depression), you wouldn't be able to take part. Also, if you can't have a brain MRI scan for medical reasons (like having certain metal implants), you won't be able to join.

Pregnant women cannot participate. It's important to remember that if you decide to join, you can withdraw from the study at any time.

Kan denna studie passa dig?

Svara på dessa snabba frågor för att se om du kan vara berättigad. Detta är endast en vägledning — forskarteamet fattar det slutgiltiga beslutet.

  1. Är du mellan 40 och 85 år gammal?
  2. Is French your first language?
  3. Are you a patient at the Amiens Memory Resource and Research Centre (CMRR)?
  4. Have you been diagnosed with mild cognitive impairment or mild dementia (due to AD, LBD, or FTLD)?
  5. Do you have a social security number/coverage?
  6. Do you NOT have any metal implants that prevent an MRI scan (like certain nerve stimulators or cochlear implants)?
Svara på varje fråga för att se ditt resultat.

Vad innebär deltagande?

If you decide to take part in this study, you would likely undergo a few different types of assessments. This includes having a brain MRI scan, which uses magnets and radio waves to create detailed pictures of your brainstructure but doesn't involve radiation. You would also have a neuropsychological evaluation, which consists of various tests to check your memory, attention, problem-solving skills, and other thinking abilities. These tests might involve answering questions, solving puzzles, or remembering lists of words. Additionally, blood samples will be taken for analysis. The study doesn't mention specific visits, medication, or a set follow-up schedule, so these details would need to be clarified with the study team. You always have the right to withdraw from the study at any point.

Potentiella risker och fördelar

Taking part in this study might help us learn more about Alzheimer's disease, which could benefit future patients. The specific benefits for you might include a thorough evaluation of your cognitive function and brain health. Potential risks are generally low, mainly associated with the MRI scan (e.g., discomfort in the scanner, but serious risks are rare if you meet the safety criteria) and blood draws (e.g., bruising or slight pain). There are no experimental medications involved. Remember, your participation is completely voluntary, and you can withdraw from the study at any time without explaining why, and it won't affect your medical care.

Platser (1)

  • CHU Amiens
    Verifierat postnummer
    Amiens, Frankrike· Rekrytering

Vanliga frågor

What is 'motor slowing'?

It means a slowdown in your physical movements and how quickly you react, often linked to how fast your brain processes information.

Kommer jag att behöva ta några nya mediciner?

No, this study does not involve giving you any new or experimental medications.

Vad är en MR-skanning?

It's a special scan that uses strong magnets and radio waves to take detailed pictures inside your body, like your brain, and it doesn't use X-rays.

Hur länge kommer studien att pågå för mig?

The study description doesn't specify the exact duration for individual participants, so you would need to ask the study team for this information.

Can I stop being part of the study once I've started?

Yes, you are free to leave the study at any point, for any reason, and it will not affect your medical care.

Hur du får reda på mer

Daniela ANDRIUTA, PhD

andriuta.daniela@chu-amiens.fr +33 3 22 66 82 40 Officiell rättegångsprotokoll

Prata alltid med din läkare eller specialist innan du bestämmer dig för att delta i en studie.

Intresserad av att delta?

Registrera ditt intresse

Dela dina uppgifter och forskarteamet för "Motor Slowing and Its Lesion-related Correlates in Alzheimer…" kommer att kontakta dig om du kan vara berättigad. Prata alltid med din läkare innan du går med på att delta.

Diskussion

Gemenskapsdiskussion

Drivs av vårt forum på community.patient.info. Var vänlig och respektfull — detta är inte medicinsk rådgivning.