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Exercise Training and Endothelial Function in Type 1 Diabetes

This research is investigating whether exercise can improve blood vessel health in adults with Type 1 diabetes (T1D). Many people with T1D can experience problems with their blood vessels early on, even before they notice any symptoms. This study aims to find out if a non-drug approach, like exercise, can help prevent or improve these issues. We're looking at how exercise affects both large and small blood vessels, and how it might impact the body's energy use and brain health. We hope to show that exercise can offer a simple, natural way to support blood vessel function and overall health for people living with Type 1 diabetes.

Överblick

Status
Rekrytering
Fas
NA
Sponsor
Universitetssjukhuset, Lille
Inskrivningsmål
34
Starta
12 Nov 2019
Beräknad slutförande
01 nov 2028

Vad handlar denna studie om?

This study is called 'Exercise Training and Endothelial Function in Type 1 Diabetes.' It's looking at how exercise might help the blood vessels in people who have Type 1 diabetes. Think of your blood vessels like tiny pipes that carry blood all around your body. In people with Type 1 diabetes, these pipes can sometimes start to show problems early on, even before they cause any noticeable symptoms. This is what we call 'endothelial dysfunction' – it simply means the inner lining of these blood vessels isn't working as well as it should. The researchers want to find natural ways, besides medication, to keep these blood vessels healthy.

The main goal of this particular study is to see if regular exercise can make a positive difference to how these blood vessels work in adults with Type 1 diabetes. The participants in this study are adults who have Type 1 diabetes but haven't yet developed any of the common complications associated with it, like kidney problems or eye damage. The researchers believe that exercise could be a safe and effective way to protect blood vessel health.

They will also be looking at other things, such as how exercise affects smaller blood vessels, larger blood vessels, and how well blood flows to your tissues during exercise. They're also interested in how exercise might impact your body's energy use and brain health. Researchers expect that this exercise programme will improve how blood vessels work, especially the inner lining, and also improve how the body uses energy. This could be a really important step in finding simple, everyday ways to help people with Type 1 diabetes stay healthier for longer.

Viktiga punkter

  • Looks at how exercise affects blood vessels in Type 1 diabetes.
  • Focuses on adults aged 18-50 without diabetes complications.
  • Aims for a non-drug way to improve health.
  • May involve an exercise programme vs. usual activity.
  • Could help us understand how to prevent diabetes complications.
  • Du kan dra dig ur studien när som helst.

Vem kan vara berättigad?

This study is looking for adults aged between 18 and 50 years old who have Type 1 diabetes. To be included, you must have been diagnosed with Type 1 diabetes for at least one year and, importantly, you must not have any signs of existing diabetes-related complications, such as problems with your eyes, kidneys, or nerves. You also need to be covered by social security.

There are several reasons why someone might not be able to join the study. For example, if you've been diagnosed with Type 1 diabetes for less than a year, or if you have other types of diabetes like Type 2. You also can't take part if you already have diabetes-related complications, if you are a smoker, or if you have high blood pressure. They are also unable to include people who are very overweight (with a Body Mass Index over 30), or if you have other chronic health conditions (apart from Type 1 diabetes itself). If you have any ongoing pain that makes it difficult to move your body, or if you've had a head injury in the past, you also won't be able to participate. This is to make sure the study focuses on the effects of exercise in a specific group of people.

Kan denna studie passa dig?

Svara på dessa snabba frågor för att se om du kan vara berättigad. Detta är endast en vägledning — forskarteamet fattar det slutgiltiga beslutet.

  1. Är du mellan 18 och 50 år gammal?
  2. Have you had Type 1 diabetes for at least one year?
  3. Do you *not* have any diabetes complications like eye, kidney, or nerve problems?
  4. Är du en icke-rökare?
  5. Do you *not* have high blood pressure, and are you *not* very overweight (BMI over 30)?
Svara på varje fråga för att se ditt resultat.

Vad innebär deltagande?

The detailed information about what taking part involves isn't provided in the summary. However, in studies like this, participants are usually divided into different groups by chance (like flipping a coin). One group might follow an exercise training programme, while another might continue with their usual daily activities. You would likely have a series of appointments, which could include some health checks, blood tests, and tests to see how your blood vessels are working, both before and after the exercise period. The length of the exercise programme and the total duration of your involvement in the study would be clearly explained by the research team.

Potentiella risker och fördelar

Taking part in a study like this could offer potential benefits, such as improving your understanding of how exercise affects your body and potentially improving your blood vessel health. However, as with any exercise program, there are potential risks, such as muscle soreness or minor injuries, though these would likely be managed and supervised. All medical tests also carry a very small risk, which the research team will explain. You are always free to change your mind and withdraw from the study at any time, for any reason, without it affecting your medical care.

Platser (1)

  • Hop Claude Huriez Chu Lille
    Verifierat postnummer
    Lille, Frankrike· Rekrytering

Vanliga frågor

What is 'endothelial function'?

Endothelial function means how well the inner lining of your blood vessels works. It's important for keeping your blood vessels healthy.

Why are you studying exercise for Type 1 diabetes?

We want to see if exercise can be a natural way to help protect blood vessel health in people with Type 1 diabetes, potentially preventing future complications.

Do I need to be a super fit athlete to join?

The information doesn't say you need to be an athlete, but generally, exercise studies want people who are able to exercise safely.

Kommer jag att behöva ta ny medicin i denna studie?

This study is focused on 'non-pharmacological interventions,' which means we are looking at treatments like exercise, not new medications.

What does 'non-pharmacological' mean?

It simply means treatments that don't involve medicines, like exercise or changes to your diet.

Hur du får reda på mer

Anne Vambergue, MD,PhD

Prata alltid med din läkare eller specialist innan du bestämmer dig för att delta i en studie.

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Dela dina uppgifter och forskarteamet för "Exercise Training and Endothelial Function in Type 1 Diabete…" kommer att kontakta dig om du kan vara berättigad. Prata alltid med din läkare innan du går med på att delta.

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