Can I take Losartan and Rybelsus together?
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Ursprungligen publicerad 25 jan 2026
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Taking these two medicines together can sometimes cause your blood sugar levels to drop lower than intended. Additionally, both drugs can affect your kidney function, especially if you become dehydrated.
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Varför detta händer
Losartan (an ACE inhibitor) can increase sensitivity to insulin, which may enhance the blood-sugar-lowering effects of Rybelsus (semaglutide). Both medications can also influence blood pressure and kidney filtration.
Vad du bör göra
Tillbaka till innehållMonitor your blood sugar levels regularly, especially when starting or changing doses. Stay well-hydrated. If you experience symptoms of low blood sugar (such as shakiness, sweating, or confusion) or notice a significant change in how much you urinate, contact your doctor. Your doctor may need to adjust your dosages.
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Viktiga försiktighetsåtgärder
Tillbaka till innehållGraviditet
You must not take losartan if you are pregnant. It can cause serious harm or death to an unborn baby, especially if taken during the second and third trimesters.
Pankreatit
Stop taking Rybelsus and seek immediate medical help if you experience severe, persistent stomach pain (which may reach through to your back), as this can be a sign of an inflamed pancreas (pancreatitis).
Thyroid cancer
Do not take Rybelsus if you or any of your family have ever had medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). Contact your doctor immediately if you notice a lump or swelling in your neck.
Diabetic eye disease (retinopathy) - Rybelsus
Inform your doctor if you have a history of diabetic retinopathy. Rapid improvements in blood sugar levels can cause a temporary worsening of this condition.
Varningar för mat och dryck
Tillbaka till innehållAlkohol
It is best to avoid or strictly limit alcohol while taking losartan. Alcohol can increase the blood pressure-lowering effect of losartan, which may make you feel dizzy, lightheaded, or faint, especially when standing up. Combining alcohol with medication also increases the risk of liver damage.
It is best to avoid or strictly limit alcohol while taking Rybelsus. Both alcohol and Rybelsus can lower your blood sugar levels; combining them increases the risk of severe hypoglycaemia (low blood sugar). Additionally, Rybelsus can cause nausea and vomiting, which alcohol may worsen.
Potassium-rich foods (e.g., bananas, spinach, salt substitutes)
Losartan can increase the levels of potassium in your blood. You should avoid using salt substitutes containing potassium (such as Lo-Salt) and speak to your doctor before significantly increasing your intake of potassium-rich foods, as high potassium levels can affect your heart rhythm.
All food and drink (Timing)
Rybelsus must be taken on an empty stomach first thing in the morning. You must wait at least 30 minutes after taking the tablet before having your first food, drink (other than a small sip of plain water), or any other oral medicines. If you eat or drink too soon, the medicine will not be absorbed properly and will not work.
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Användning av andra läkemedel
Tillbaka till innehållTaking multiple medicines? Our Interaktionskontroll för läkemedel helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Ansvarsfriskrivning
Denna information är endast avsedd för allmän utbildning och bör inte användas som en ersättning för professionell medicinsk rådgivning. Rådfråga alltid din läkare, apotekare eller annan kvalificerad vårdpersonal innan du fattar beslut om dina mediciner. Individuella omständigheter kan variera, och endast en vårdpersonal som känner till din medicinska historia kan ge personlig vägledning.
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Informationen på denna sida är skriven och granskad av kvalificerade kliniker.
25 jan 2026 | Ursprungligen publicerad

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