Co-amoxiclav for infections
Augmentin
Granskad av Sid DajaniSenast uppdaterad av Michael Stewart, MRPharmSLast updated 22 Nov 2023
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Make sure you tell your doctor if you are allergic to penicillin. Co-amoxiclav is a type of penicillin - do inte take it if you are allergic to penicillin.
Space your doses out evenly over the day and complete the full course of this antibiotic, even if you feel your infection has cleared up. You can take co-amoxiclav before or after food.
The most common side effect of co-amoxiclav is diarrhoea.
If you have an allergic reaction (such as any swelling around your mouth, any difficulties breathing or a red rash) contact a doctor for advice straightaway.
At a glance
Co-amoxiclav is an antibiotic used to treat bacterial infections like those in sinuses, urine, and skin.
Common side effects include diarrhoea, feeling sick, being sick, and thrush.
Taking doses at mealtime can help reduce feelings of sickness.
Drink plenty of water and finish the full course of medicine, even if you feel better.
Do not take co-amoxiclav if you suspect glandular fever or have a penicillin allergy.
Seek immediate medical help for an itchy rash, swollen face, or breathing difficulties.
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About co-amoxiclav
Typ av medicin | Penicillin antibiotic |
Används för | Infektioner (hos vuxna och barn) |
Även kallad | Augmentin® |
Tillgänglig som | Tabletter, flytande medicin och injektion |
What is co-amoxiclav used for?
Tillbaka till innehållCo-amoxiclav is a type of antibiotic used to treat bacterial infections. It is commonly prescribed for:
Skin infections.
Joint infections.
Some dental infections.
It is also given before some surgical operations, to prevent an infection from developing.
Co-amoxiclav contains two ingredients, amoxicillin and clavulanic acid. The first ingredient, amoxicillin, is a penicillin antibiotic which treats infection by killing the bacteria responsible for the infection.
Some bacteria are able to produce a chemical which makes amoxicillin less effective. The second ingredient, clavulanic acid, stops this from happening. Clavulanic acid stops the chemical produced by the bacteria from working, and this allows the amoxicillin to kill the bacteria.
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Side effects of co-amoxiclav
Tillbaka till innehållCommon side effects of co-amoxiclav include:
Diarré.
Känna sig illamående (illamående).
Kräkningar.
Oral or vaginal thrush.
You will find a full list in the manufacturer's information leaflet supplied with your medicine.
How to manage co-amoxiclav side effects
Tillbaka till innehållThe unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common co-amoxiclav side effects | Vad kan jag göra om jag upplever detta? |
Diarré | Drink plenty of water to replace any lost fluids. If the diarrhoea continues, becomes severe, or contains blood, let your doctor know straightaway |
Feeling sick or being sick | You can reduce this by taking your doses at a mealtime |
Redness and itching in the mouth or vagina (thrush) | Speak with your doctor for advice about treatment |
Viktigt: if you develop an itchy rash, swollen face or mouth, or have difficulty breathing, these may be signs that you are allergic to a penicillin antibiotic. Do not take any more co-amoxiclav and speak with your doctor or go to your local accident and emergency department straightaway.
If you experience any other symptoms which you think may be due to the antibiotic, speak with your doctor or pharmacist for further advice.
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Who should not take co-amoxiclav?
Tillbaka till innehållSome medicines aren’t suitable for everyone. Before taking co-amoxiclav your doctor or pharmacists needs to know if:
If you suspect you may have glandular fever.
If you have an allergic condition, or if you have ever had an allergic reaction to a medicine. This is especially important if you have ever had a bad reaction to any penicillin antibiotic.
If you are pregnant or breastfeeding. Co-amoxiclav is not known to be harmful to babies; however, it is still important that you tell your doctor if you are expecting or breastfeeding a baby.
If you have any problems with the way your liver works, or problems with the way your kidneys work.
Om du tar några andra läkemedel. Detta inkluderar alla läkemedel du tar som finns att köpa utan recept, samt växtbaserade och komplementära läkemedel.
How to take co-amoxiclav
Tillbaka till innehållRead the leaflet inside the pack before starting treatment to learn more about co-amoxiclav and its possible side effects.
Take co-amoxiclav exactly as your doctor tells you.
It is usually taken three times a day, about every eight hours, spaced evenly throughout the day.
Check the label on the pack to see how many tablets or how much liquid medicine to take for each dose.
If you are giving liquid medicine to a child, follow the directions carefully and measure the correct amount.
Drink plenty of water while taking co-amoxiclav to help keep your kidneys working well.
You can take your doses either before or after food.
If you forget a dose, take it as soon as you remember, but do not take two doses at the same time.
Få ut det mesta av din behandling
Tillbaka till innehållThe liquid form of co-amoxiclav may temporarily stain teeth, but this should disappear after the antibiotic course ends.
Finish the full course of antibiotics even if you feel better, unless your doctor tells you to stop.
Treatment usually lasts no longer than 14 days, and you should see your doctor if you still feel unwell after finishing it.
Antibiotics can sometimes cause thrush (redness and itching in the mouth or vagina); speak to your doctor or pharmacist if this happens.
If you take the contraceptive pill, vomiting or diarrhoea lasting more than 24 hours may reduce its effectiveness, so ask about extra contraception.
Co-amoxiclav may affect the oral typhoid vaccine, so tell healthcare staff you are taking it before any vaccinations.
How to store co-amoxiclav
Tillbaka till innehållFörvara alla läkemedel utom räckhåll och synhåll för barn.
Keep co-amoxiclav liquid medicine in a refrigerator, and do not use it after the expiry date on the bottle. It will have been made up by the pharmacy and it is important you do not store or use it for longer than seven days since the date it was made up.
Store co-amoxiclav tablets in a cool, dry place, away from direct heat and light.
Viktig information om alla läkemedel
Tillbaka till innehållViktig information om alla läkemedel
Ta aldrig mer än den föreskrivna dosen. Om du misstänker att du eller någon annan kan ha tagit en överdos av denna medicin, gå till akutmottagningen på ditt lokala sjukhus. Ta med behållaren, även om den är tom.
Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.
Om du köper några mediciner, kontrollera med en apotekare att de är säkra att ta tillsammans med dina andra mediciner.
Om du ska genomgå en operation eller någon tandbehandling, informera den som utför behandlingen om vilka mediciner du tar.
Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.
Om du har några frågor om denna medicin, fråga din apotekare.
MHRA - Rapportera biverkningar
Rapportera misstänkta biverkningar av läkemedel, vacciner, e-cigaretter, medicintekniska händelser, defekta eller förfalskade (falska) produkter till Läkemedelsverket för att säkerställa säker och effektiv användning.
Vanliga frågor
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Kontrollera möjliga interaktioner mellan läkemedel, kosttillskott och livsmedel innan du tar dem tillsammans.
Vidare läsning och referenser
- Manufacturer's PIL, Augmentin® 375 mg tablets; GlaxoSmithKline UK, The electronic Medicines Compendium. Dated July 2022.
- Manufacturer's PIL, Augmentin® 125/31 SF Suspension; GlaxoSmithKline UK, The electronic Medicines Compendium. Dated July 2022.
- Mediciner Komplett BNF 89:e Utgåvan; Brittiska Läkarföreningen och Kungliga Farmaceutiska Sällskapet i Storbritannien, London.
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About the authorView full bio

Michael Stewart, MRPharmS
Medicine Leaflet Review Manager – Contractor, Pharmacist
BPharm (Hons), MRPharmS
Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.
About the reviewer

Sid Dajani
Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.
Artikelhistorik
Informationen på denna sida är skriven och granskad av kvalificerade kliniker.
Next review due: 21 Nov 2026
22 Nov 2023 | Senaste versionen

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