Eslicarbazepine for epilepsy
Zebinix
Granskad av Sid DajaniSenast uppdaterad av Michael Stewart, MRPharmSLast updated 18 Dec 2023
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Take eslicarbazepine once each day.
The most common side-effects are feeling sleepy or dizzy.
You need to take eslicarbazepine regularly to prevent seizures from occurring. Do not stop taking it unless your doctor tells you to.
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About eslicarbazepine
Typ av medicin | An antiepileptic medicine |
Används för | Epilepsy with partial seizures |
Även kallad | Zebinix® |
Tillgänglig som | Tabletter och flytande medicin för oral användning |
Having epilepsy means that you have had more than one otherwise unexplained fit, or seizure. A seizure is a short episode of symptoms caused by a burst of abnormal electrical activity in your brain. With partial seizures (also called focal seizures), the burst of electrical activity is in one part of your brain and therefore you tend to have localised or 'focal' symptoms. Because different parts of the brain control different functions, your symptoms will depend on which part of your brain is affected. Partial seizures can sometimes develop into seizures which affect all of your brain. These are called secondary generalised seizures. Symptoms that may occur during a seizure can affect your muscles, sensations, behaviour, emotions, consciousness, or a combination of these. The seizures can be prevented in most people by suitable antiepileptic medication. Eslicarbazepine works alongside other antiepileptic medicines to stabilise the electrical activity of your brain. This helps to prevent seizures from occurring.
Before taking eslicarbazepine
Tillbaka till innehållSome medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking eslicarbazepine it is important that your doctor knows:
Om du är gravid, försöker bli gravid eller ammar.
If you have any problems with the way your kidneys work, or with the way your liver works.
Om du har en hjärtsjukdom.
If you have been told you have low amounts of sodium in your blood.
Om du tar några andra läkemedel. Detta inkluderar alla läkemedel du tar som finns att köpa utan recept, samt växtbaserade och komplementära läkemedel.
Om du någonsin har haft en allergisk reaktion mot en medicin.
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How to take eslicarbazepine
Tillbaka till innehållBefore you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about eslicarbazepine and will provide you with a full list of the side-effects which you may experience from taking it.
Take eslicarbazepine exactly as your doctor tells you to. Your dose will be printed on the label of the pack to remind you about what the doctor said. It is usual to start treatment on a low dose, and then for the dose to be increased gradually to a regular maintenance dose. Most people will be prescribed 400 mg a day to begin with (taken as half of an 800 mg tablet or two 200 mg tablets), and then the dose will be increased after a week or so, to one 800 mg tablet each day.
It is important you try to take your doses at the same time of day, each day. Having a routine will help you to remember to take your doses regularly.
You can take eslicarbazepine either before or after meals.
Swallow the tablet with a drink of water.
If you forget to take a dose, take it as soon as you remember. If you do not remember until the following day, skip the forgotten dose. Do not take two doses at the same time to make up for a missed dose.
Få ut det mesta av din behandling
Tillbaka till innehållWhen you first start a new treatment for epilepsy there may be a change in the number or type of seizures you experience. Your doctor will advise you about this.
Försök att hålla dina regelbundna möten med din läkare. Detta är så att din läkare kan följa upp din utveckling.
If you buy any medicines, check with a pharmacist that they are suitable for you to take with your antiepileptic medication.
Different formulations of some antiepileptic medicines can act in a slightly different way in your body. Because of this, your doctor may recommend that you continue to take eslicarbazepine from the same manufacturer each time you obtain a new supply. If so, each time you collect a prescription, check to make sure your supply looks the same and that the name is the same. If you are unsure, or if you have any questions about your prescription, please ask your pharmacist to advise you.
While you are being treated for epilepsy there is a small risk that you may develop mood changes, distressing thoughts and feelings about suicide. If this happens, you must tell your doctor about it straightaway.
People with epilepsy must stop driving at first. Your doctor will advise you about when it may be possible for you to start driving again. This will usually be after a year free of seizures.
Many antiepileptic medicines can harm an unborn child. If you are a woman, make sure you have discussed with your doctor which types of contraception are suitable for you and your partner. Eslicarbazepine can make oral contraceptives less effective. Your doctor will advise you on other types of contraception such as an intra-uterine device (IUD) and barrier methods. If you want to have a family, discuss this with your doctor so that you can be given advice from a specialist before you become pregnant.
You need to take eslicarbazepine regularly every day. Do not stop taking it unless your doctor tells you to stop. Stopping treatment suddenly can cause problems and your doctor will probably want you to reduce your dose gradually if this becomes necessary.
If you drink alcohol, ask your doctor for advice. Your doctor may advise you not to drink alcohol while you are on this medicine.
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Can eslicarbazepine cause problems?
Tillbaka till innehållAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with eslicarbazepine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Very common eslicarbazepine side-effects (these affect more than 1 in 10 people) | Vad kan jag göra om jag upplever detta? |
Feeling dizzy or sleepy | Do not drive and do not use tools or machines |
Common eslicarbazepine side-effects (these affect fewer than 1 in 10 people) | Vad kan jag göra om jag upplever detta? |
Feeling tired, blurred or double vision | Do not drive and do not use tools or machines |
Huvudvärk | Drick mycket vatten och be din apotekare rekommendera en lämplig smärtstillande. Om huvudvärken fortsätter, informera din läkare |
Feeling sick (nausea) or being sick (vomiting) | Stick to simple meals - avoid rich or spicy food |
Diarré | Drick mycket vatten för att ersätta de förlorade vätskorna |
Feeling unsteady, difficulty concentrating, weight gain, feeling shaky, a spinning sensation (vertigo), skin rash, sleeping problems, lack of appetite | If any of these become troublesome, speak with your doctor for advice |
If you develop a severe skin rash or experience any other symptoms which you think may be due to the tablets, speak with your doctor or pharmacist for advice as soon as possible.
How to store eslicarbazepine
Tillbaka till innehållFörvara alla läkemedel utom räckhåll och synhåll för barn.
Förvara på en sval, torr plats, borta från direkt värme och ljus.
The oral liquid medicine keeps for two months after first opening. After this time make sure you use a new bottle. It is a good idea to write the date you opened the bottle on the label.
Viktig information om alla läkemedel
Tillbaka till innehållViktig information om alla läkemedel
Ta aldrig mer än den föreskrivna dosen. Om du misstänker att du eller någon annan kan ha tagit en överdos av denna medicin, gå till akutmottagningen på ditt lokala sjukhus. Ta med behållaren, även om den är tom.
Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.
Om du ska genomgå en operation eller tandbehandling, informera den som utför behandlingen om vilka mediciner du tar.
Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.
Om du har några frågor om denna medicin, fråga din apotekare.
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Vidare läsning och referenser
- Manufacturer's PIL, Zebinix® 800 mg tablets; Bial Pharma UK Ltd, The electronic Medicines Compendium. Dated January 2021.
- Manufacturer's PIL, Zebinix® 50 mg/ml oral suspension; Bial Pharma UK Ltd, The electronic Medicines Compendium. Dated January 2021.
- Mediciner Komplett BNF 89:e Utgåvan; Brittiska Läkarföreningen och Kungliga Farmaceutiska Sällskapet i Storbritannien, London.
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About the authorView full bio

Michael Stewart, MRPharmS
Medicine Leaflet Review Manager – Contractor, Pharmacist
BPharm (Hons), MRPharmS
Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.
About the reviewer

Sid Dajani
Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.
Artikelhistorik
Informationen på denna sida är skriven och granskad av kvalificerade kliniker.
Next review due: 17 Dec 2026
18 Dec 2023 | Senaste versionen

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