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Ethosuximid för epilepsi

Emeside, Epesri

Take ethosuximide regularly. Most people are prescribed two doses a day.

Do not stop taking it unless your doctor tells you to.

Ethosuximide may make you feel sick (nausea) when you first start taking it. This should soon settle down.

Överblick

  • Ethosuximide is a medicine used to treat absence seizures in epilepsy, mainly in children and young people.

  • It helps reduce seizures by stabilising abnormal electrical activity in the brain.

  • Take ethosuximide exactly as your doctor tells you, usually twice a day.

  • A common side-effect is feeling sick, abdominal discomfort, or headaches.

  • If you experience mood changes or distressing thoughts, tell your doctor straightaway.

  • Do not stop taking ethosuximide suddenly, as this can cause problems.

  • If you have a high temperature, mouth ulcers, or unexplained bruising, contact your doctor immediately.

About ethosuximide

Typ av medicin

An antiepileptic medicine

Används för

Epilepsy with absence seizures

Även kallad

Emeside®, Epesri®

Tillgänglig som

Capsules and oral liquid medicine

Absence seizures are a form of epilepsy. They mainly occur in children and young people. Absence seizures are a brief loss of consciousness (an 'absence') for a few seconds, and can appear like daydreaming. Although no underlying cause for this type of seizure can be found, it is thought that the brain develops a low threshold for bursts of abnormal electrical activity. Ethosuximide is one of the medicines commonly prescribed for this type of epilepsy. It helps to reduce absence seizures by stabilising the abnormal electrical activity in the brain.

Ethosuximide is occasionally prescribed for some other types of seizures.

Before taking ethosuximide

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you (or your child if you are the carer) start taking ethosuximide it is important that your doctor knows:

  • Om du är gravid, försöker bli gravid eller ammar.

  • If you have any problems with the way your kidneys work, or with the way your liver works.

  • Om du har en sällsynt ärftlig blodsjukdom som kallas porfyri.

  • Om du tar några andra läkemedel. Detta inkluderar alla läkemedel du tar som finns att köpa utan recept, samt växtbaserade och komplementära läkemedel.

  • Om du någonsin har haft en allergisk reaktion mot en medicin.

How to take ethosuximide

  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about ethosuximide and will provide you with a full list of the side-effects which you may experience from taking it.

  • Take ethosuximide exactly as your doctor tells you to. Your dose will be printed on the label of the pack of medicine to remind you about what the doctor said. It is usual to start treatment on a low dose, and then for the dose to be increased gradually to a regular maintenance dose. It is usual to take two doses each day. Doses for children are tailored to their age and weight.

  • Try to take your doses at the same times of day, each day. Having a routine will help you to remember to take your doses regularly. You can take ethosuximide either before or after meals. If you are taking capsules, swallow them with a drink of water.

  • If you (or your child) have been given ethosuximide oral liquid medicine, remember to shake the bottle well before you measure out the dose. It is also a good idea to brush your (or your child's) teeth after each dose as the medicine contains sugar.

  • If you forget to take a dose, take it as soon as you remember, unless it is nearly time for your next dose, in which case leave out the missed dose. Do not take two doses together to make up for a forgotten dose.

Få ut det mesta av din behandling

  • When you first start a new treatment for epilepsy there may be a change in the number or type of seizures you experience. Your doctor will advise you about this.

  • Försök att hålla dina regelbundna möten med din läkare. Detta är så att din läkare kan följa upp din utveckling.

  • Different formulations and makes of ethosuximide can act in a slightly different way in your body. Because of this, your doctor may recommend that you continue to take ethosuximide from the same manufacturer each time you obtain a new supply. If so, each time you collect a prescription, check to make sure your supply looks the same and that the name is the same. If you are unsure, or if you have any questions about your prescription, please ask your pharmacist to advise you.

  • If you buy any medicines, check with a pharmacist that they are suitable for you to take.

  • While you are being treated for epilepsy there is a small risk that you may develop mood changes, distressing thoughts and feelings about suicide. If this happens, you must tell your doctor about it straightaway.

  • People with epilepsy must stop driving at first. Your doctor will advise you about when it may be possible for you to start driving again. This will usually be after a year free of seizures.

  • Antiepileptic medicines can harm an unborn child. If you are a woman, make sure you have discussed with your doctor which types of contraception are suitable for you and your partner. If you want to have a family, discuss this with your doctor so that you can be given advice from a specialist before you become pregnant.

  • You need to take ethosuximide regularly every day. Do not stop taking it unless your doctor tells you to stop. Stopping treatment suddenly can cause problems and your doctor will want you to reduce your dose gradually if this becomes necessary.

  • If you drink alcohol, ask your doctor for advice. Your doctor may advise you not to drink alcohol while you are on this medicine.

Can ethosuximide cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with ethosuximide. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Common ethosuximide side-effects (these affect less than 1 in 10 people)

Vad kan jag göra om jag upplever detta?

Feeling sick (nausea) or being sick (vomiting), tummy (abdominal) discomfort

Try to stick to simple meals - avoid rich or spicy foods

Huvudvärk

Drick mycket vatten och be din apotekare rekommendera en lämplig smärtstillande. Om huvudvärken fortsätter, informera din läkare

Feeling dizzy, tired or sleepy

If this happens, do not drive and do not use tools or machines

Diarré

Drick mycket vatten för att ersätta de förlorade vätskorna

Lack of appetite, feeling unsteady, itchy skin rash, mood changes

If any of these become troublesome, speak with your doctor for advice

Viktigt: your doctor will discuss with you the possibility that ethosuximide can cause blood disorders. Although these occur less commonly than the side-effects listed above, it is important that you contact your doctor omedelbart if you experience any of the following symptoms:

  • A high temperature (fever).

  • Mouth ulcers.

  • Unexplained bruising or bleeding.

If you experience any other symptoms which you think may be due to ethosuximide, speak with your doctor or pharmacist for further advice.

How to store ethosuximide

  • Förvara alla läkemedel utom räckhåll och synhåll för barn.

  • Förvara på en sval, torr plats, borta från direkt värme och ljus.

Viktig information om alla läkemedel

Viktig information om alla läkemedel

Ta aldrig mer än den föreskrivna dosen. Om du misstänker att du eller någon annan kan ha tagit en överdos av denna medicin, gå till akutmottagningen på ditt lokala sjukhus. Ta med behållaren, även om den är tom.

Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.

Om du ska genomgå en operation eller tandbehandling, informera den som utför behandlingen om vilka mediciner du tar.

Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.

Om du har några frågor om denna medicin, fråga din apotekare.

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Vanliga frågor

Can I take other medicines, including over-the-counter remedies or herbal supplements, while on ethosuximide?

It's important to inform your doctor about any other medicines you are taking, including those available without a prescription, as well as herbal and complementary medicines. This is because some medicines may not be suitable to take with ethosuximide, or may require extra care.

How soon should I expect to see a difference in my seizures after starting ethosuximide?

When you first start a new epilepsy treatment like ethosuximide, there might be a change in the number or type of seizures you experience. Your doctor will provide specific advice regarding expectations for your individual situation.

Are there any specific concerns about ethosuximide if I have kidney or liver problems?

Yes, if you have any problems with how your kidneys or liver work, it's important to tell your doctor before starting ethosuximide. They will need to know this information to ensure the medicine is appropriate for you and to take any necessary precautions.

What should I do if I notice an itchy skin rash after taking ethosuximide?

An itchy skin rash can be a side-effect of ethosuximide. If this becomes troublesome, you should speak with your doctor for advice.

If I switch to a different brand or formulation of ethosuximide, will it affect my treatment?

Different formulations and brands of ethosuximide can act slightly differently in your body. Your doctor might recommend that you consistently use ethosuximide from the same manufacturer. If this is the case, always check your new supply to ensure it looks and is named the same. If you have any concerns, ask your pharmacist.

What are the signs of blood disorders that I should watch out for while taking ethosuximide?

While less common than other side-effects, ethosuximide can cause blood disorders. You should contact your doctor immediately if you experience a high temperature (fever), mouth ulcers, or unexplained bruising or bleeding.

Vidare läsning och referenser

Om författarenVisa fullständig biografi

Författarbild

Michael Stewart, MRPharmS

Ansvarig för granskning av medicinbroschyrer – Konsult, Apotekare

BPharm (Hons), MRPharmS

Michael är en apotekare som arbetar i Midlands och South Yorkshire med mer än 20 års erfarenhet av att ge råd om läkemedel och medicinska tillstånd. Han har en stark bakgrund inom vårdutbildning och har producerat och levererat utbildningskurser för apoteksteam och personal inom vårdboenden, inklusive sjuksköterskor. Han har också bidragit till apoteksrådgivande styrelser för hantering av mindre allvarliga tillstånd i samhället.

Om recensenten

Författarbild

Sid Dajani

Sultan Dajani tog examen vid London School of Pharmacy 1994 och blev den yngsta valda medlemmen i Royal Pharmaceutical Society-rådet sedan dess grundande 1842.

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