Hoppa till huvudinnehåll

Fluphenazine long-acting injection

discontinued

Clinical author's note Michael Stewart 05/12/2022: Modecate® injections were discontinued in the United Kingdom in November 2020. At the time of review there are no licensed injection products containing fluphenazine available in the UK. Fluphenazine injections may still be available in other countries or as special order products. This medicine leaflet is based on medical information available in the UK at the time of writing and is left here for reference purposes. Please also refer to the manufacturer's information supplied with your medicine.

Fluphenazine long-acting injection will be given to you by your clinic doctor or nurse every 2-5 weeks.

If you miss an appointment for an injection, make another appointment as soon as possible.

If you either start or stop smoking whilst you are being treated with fluphenazine, tell your doctor. Your dose may need to be adjusted.

At a glance

  • Fluphenazine long-acting injection is an antipsychotic medicine for adults with schizophrenia.

  • It is a 'depot' injection given into a muscle every 2–5 weeks to maintain symptom control.

  • Tell your doctor about any heart, liver, or kidney problems, or if you are pregnant or breastfeeding.

  • Do not drive or use tools if you feel sleepy, dizzy, or have blurred vision.

  • Contact your doctor immediately if you have muscle stiffness, high temperature, confusion, or a fast heartbeat.

Fortsätt läsa nedan

About fluphenazine long-acting injection

Typ av medicin

An antipsychotic injection

Används för

Maintenance of symptom control in adults with schizophrenia and other similar mental health problems

Även kallad

Fluphenazine decanoate; Modecate® (discontinued)

Tillgänglig som

Long-acting 'depot' injection

Fluphenazine belongs to a group of medicines called antipsychotics. You will have been prescribed it to maintain symptom control of schizophrenia.

Schizophrenia is a mental health condition that causes disordered ideas, beliefs and experiences. Symptoms of schizophrenia include hearing, seeing, or sensing things that are not real, having mistaken beliefs, feeling unusually suspicious, and becoming withdrawn. Fluphenazine is used to relieve the symptoms of schizophrenia and other similar mental health problems. It works on the balance of chemical substances in your brain.

Long-acting, or 'depot', injections are used once your symptoms have been eased by taking tablets. The injection slowly releases fluphenazine into your body and is given every 2-5 weeks. The main advantage of a depot injection is that you do not have to remember to take tablets every day.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start having fluphenazine injections, it is important that your doctor knows:

  • Om du är gravid eller ammar.

  • If you know you have a heart condition or blood vessel disease (such as any thickening of the arteries in your head).

  • Om du har några problem med hur din lever fungerar, eller om du har några problem med hur dina njurar fungerar.

  • If you have prostate problems.

  • If you have a blood disorder.

  • If you have any problems with your breathing.

  • If you have any of the following: epilepsy, depression, Parkinson's disease, raised pressure in your eye (glaucoma), thyroid problems, or a condition which causes muscle weakness, called myasthenia gravis.

  • If you have ever had yellowing of your skin or the whites of your eyes (jaundice).

  • If you have a tumour on your adrenal gland (a condition called phaeochromocytoma).

  • If you have had an allergic reaction to a medicine.

  • Om du tar eller använder några andra läkemedel. Detta inkluderar alla läkemedel du tar som finns att köpa utan recept, samt växtbaserade och komplementära läkemedel.

Fortsätt läsa nedan

  • Before you start this treatment, ask to read the manufacturer's printed information leaflet from inside the pack. The leaflet will give you more information about fluphenazine, and it will also provide you with a full list of the side-effects which you could experience.

  • Fluphenazine long-acting injection will be given to you by a doctor or nurse. If you haven't received an injection like fluphenazine before, a small dose is usually given as a test 4-7 days before you have a full dose. This is to see how well you tolerate the injection. The injection is given into a muscle in your bottom (buttocks).

  • You may be asked to continue taking your currently prescribed tablets for a short while after you have had your first injection. This is because it can take a few weeks before you feel the full effect from the injection.

  • Treatment with fluphenazine is usually long-term so that your symptoms don't return.

  • Your treatment will require careful monitoring to make sure that you get the best possible benefit from fluphenazine. Keep your regular doctor's appointments so that you get your injections on time, and your progress can be checked. If you miss an appointment for an injection, contact your doctor to arrange for another appointment as soon as possible.

  • Medicines similar to fluphenazine can cause people to become more sensitive to sunlight than normal. It is recommended that you avoid strong sunlight and sunbeds, and use a sun cream with a high sun protection factor even on bright but cloudy days.

  • If you drink alcohol, ask your doctor for advice about drinking while you are on fluphenazine. Alcohol can increase the chance that you experience side-effects and may not be advisable for you.

  • Smoking can interfere with the way your body handles fluphenazine. If you either start smoking or quit smoking whilst you are having fluphenazine, please make sure that you tell your doctor. It is probable that your dose will need to be adjusted.

  • If you have diabetes you may need to check your blood glucose more frequently, as fluphenazine can affect the levels of sugar in your blood. Your doctor will advise you about this.

  • If you are having any dental treatment or an operation, tell the person carrying out the treatment that you have had a fluphenazine injection. This is important because it may interfere with the anaesthetic or painkillers you receive.

  • If you buy or take any 'over-the-counter' medicines, check with a pharmacist that they are suitable for you to take with fluphenazine.

Fortsätt läsa nedan

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the ones associated with fluphenazine. The best place to find a full list of the side-effects which can be associated with your injection, is from the manufacturer's printed information leaflet supplied with the medicine. Alternatively, you can find an example of a manufacturer's information leaflet in the reference section below. Speak with your doctor or pharmacist if any of the following continue or become troublesome.

Fluphenazine side-effects

Vad kan jag göra om jag upplever detta?

Pain at the site of the injection

This should not last long. If the area becomes red, swollen or 'lumpy', let your doctor know

Feeling sleepy or dizzy, blurred vision

Kör inte och använd inte verktyg eller maskiner när du är påverkad

Torr mun

Försök tugga sockerfritt tuggummi eller suga på sockerfria karameller

Unusual or uncontrollable muscle movements, feeling shaky

Speak with your doctor about these

Feeling restless, movement problems

Speak with your doctor

Huvudvärk

Drink plenty of water and ask your pharmacist to recommend a suitable painkiller. If the headaches continue, speak with your doctor

Changes in weight, stuffy nose, difficulty sleeping, feeling agitated or confused, sexual problems, breast changes, menstrual problems, fast heartbeats, poor judgement or reduced mental ability, stomach upset, constipation, and difficulty passing urine

Discuss these with your doctor if any become troublesome

Viktigt: if you experience symptoms such as muscle stiffness, a very high temperature, feeling confused or sweaty, a fast heartbeat, and urinary incontinence, you should contact your doctor immediately. These can be signs of a rare but serious condition known as neuroleptic malignant syndrome.

If you experience any other symptoms which you think may be due to the injection, speak with your doctor or pharmacist for further advice.

  • Förvara alla läkemedel utom räckhåll och synhåll för barn.

  • Förvara på en sval, torr plats, borta från direkt värme och ljus.

Viktig information om alla läkemedel

If you suspect that you have had an overdose of this medicine, contact the accident and emergency department of your local hospital for advice.

Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.

Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.

Om du har några frågor om denna medicin, fråga din apotekare.

Rapportera biverkningar av ett läkemedel eller vaccin

Om du upplever biverkningar kan du rapportera dem online via Yellow Card website.

symptom checker

Osäker på att blanda mediciner?

Kontrollera möjliga interaktioner mellan läkemedel, kosttillskott och livsmedel innan du tar dem tillsammans.

Vanliga frågor

What is the main benefit of having fluphenazine as a long-acting injection instead of taking tablets?

The primary advantage of the long-acting, or 'depot', injection is that you don't have to remember to take tablets every day. The injection slowly releases fluphenazine into your body and is given every 2-5 weeks, helping to maintain symptom control without daily pill-taking.

Why would I continue taking my tablets for a short time after my first injection?

You may be asked to continue taking your currently prescribed tablets for a short while after your first injection because it can take a few weeks for the full effect of the injection to begin working effectively in your body.

How often will I need to get the fluphenazine long-acting injection?

The fluphenazine long-acting injection is typically given every 2-5 weeks. It's important to keep your regular doctor's appointments to ensure you receive your injections on time and to allow your progress to be monitored.

Is it safe to drink alcohol while receiving fluphenazine injections?

If you drink alcohol, it's important to ask your doctor for advice. Alcohol can increase the chance of experiencing side-effects from fluphenazine and may not be recommended for you.

What should I do if I miss an appointment for my fluphenazine injection?

If you miss an appointment for an injection, you should contact your doctor to arrange for another appointment as soon as possible to ensure your treatment continues without disruption.

Can fluphenazine affect my blood sugar levels?

Yes, if you have diabetes, fluphenazine can affect the levels of sugar in your blood. Your doctor will advise you about this, and you may need to check your blood glucose more frequently.

Can smoking affect how fluphenazine works in my body?

Yes, smoking can interfere with how your body processes fluphenazine. If you either start or quit smoking while on this treatment, it's important to tell your doctor as your dose may need to be adjusted.

What specifically is neuroleptic malignant syndrome, and why is it important to know about?

Neuroleptic malignant syndrome is a rare but serious condition that can be caused by medicines like fluphenazine. You should contact your doctor immediately if you experience symptoms such as muscle stiffness, a very high temperature, feeling confused or sweaty, a fast heartbeat, and urinary incontinence, as these can be signs of this condition.

Vidare läsning och referenser

Fortsätt läsa nedan

About the authorView full bio

Author image

Michael Stewart, MRPharmS

Medicine Leaflet Review Manager – Contractor, Pharmacist

BPharm (Hons), MRPharmS

Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.

About the reviewer

Author image

Sid Dajani

Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.

Artikelhistorik

Informationen på denna sida är skriven och granskad av kvalificerade kliniker.

  • Next review due: 11 Jun 2027
  • 12 Dec 2022 | Senaste versionen

    Senast uppdaterad av

    Michael Stewart, MRPharmS

    Granskad av

    Sid Dajani
flu eligibility checker

Fråga, dela, anslut.

Bläddra i diskussioner, ställ frågor och dela erfarenheter inom hundratals hälsorelaterade ämnen.

Anmäl dig till Patientens nyhetsbrev

Din veckovisa dos av tydliga, pålitliga hälsoråd - skrivna för att hjälpa dig känna dig informerad, självsäker och i kontroll.

Vänligen ange en giltig e-postadress

By subscribing you accept our Sekretesspolicy. Du kan avsluta prenumerationen när som helst. Vi säljer aldrig dina uppgifter.