Flufenazin långtidsverkande injektion
discontinued
Granskad av Sid DajaniSenast uppdaterad av Michael Stewart, MRPharmSSenast uppdaterad 12 Dec 2022
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Klinisk författares anmärkning Michael Stewart 05/12/2022: Modecate® injections were discontinued in the United Kingdom in November 2020. At the time of review there are no licensed injection products containing fluphenazine available in the UK. Fluphenazine injections may still be available in other countries or as special order products. This medicine leaflet is based on medical information available in the UK at the time of writing and is left here for reference purposes. Please also refer to the manufacturer's information supplied with your medicine.
Fluphenazine long-acting injection will be given to you by your clinic doctor or nurse every 2-5 weeks.
If you miss an appointment for an injection, make another appointment as soon as possible.
If you either start or stop smoking whilst you are being treated with fluphenazine, tell your doctor. Your dose may need to be adjusted.
Överblick
Fluphenazine long-acting injection is an antipsychotic medicine given for schizophrenia and similar mental health problems.
It is a 'depot' injection given into a muscle every 2–5 weeks to maintain symptom control.
Tell your doctor about existing health conditions or medicines before starting treatment.
Avoid strong sunlight and sunbeds, and use high-factor sun cream whilst on this injection.
Keep regular appointments for injections and monitoring.
Contact your doctor immediately if you experience muscle stiffness, high temperature, confusion, sweating, fast heartbeat, and urinary incontinence.
About fluphenazine long-acting injection
Typ av medicin | An antipsychotic injection |
Används för | Maintenance of symptom control in adults with schizophrenia and other similar mental health problems |
Även kallad | Fluphenazine decanoate; Modecate® (discontinued) |
Tillgänglig som | Long-acting 'depot' injection |
Fluphenazine belongs to a group of medicines called antipsychotics. You will have been prescribed it to maintain symptom control of schizophrenia.
Schizophrenia is a mental health condition that causes disordered ideas, beliefs and experiences. Symptoms of schizophrenia include hearing, seeing, or sensing things that are not real, having mistaken beliefs, feeling unusually suspicious, and becoming withdrawn. Fluphenazine is used to relieve the symptoms of schizophrenia and other similar mental health problems. It works on the balance of chemical substances in your brain.
Long-acting, or 'depot', injections are used once your symptoms have been eased by taking tablets. The injection slowly releases fluphenazine into your body and is given every 2-5 weeks. The main advantage of a depot injection is that you do not have to remember to take tablets every day.
Before having fluphenazine long-acting injection
Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start having fluphenazine injections, it is important that your doctor knows:
Om du är gravid eller ammar.
If you know you have a heart condition or blood vessel disease (such as any thickening of the arteries in your head).
Om du har några problem med hur din lever fungerar, eller om du har några problem med hur dina njurar fungerar.
If you have prostate problems.
If you have a blood disorder.
If you have any problems with your breathing.
If you have any of the following: epilepsy, depression, Parkinson's disease, raised pressure in your eye (glaucoma), thyroid problems, or a condition which causes muscle weakness, called myasthenia gravis.
If you have ever had yellowing of your skin or the whites of your eyes (jaundice).
If you have a tumour on your adrenal gland (a condition called phaeochromocytoma).
If you have had an allergic reaction to a medicine.
Om du tar eller använder några andra läkemedel. Detta inkluderar alla läkemedel du tar som finns att köpa utan recept, samt växtbaserade och komplementära läkemedel.
How fluphenazine long-acting injection is given
Before you start this treatment, ask to read the manufacturer's printed information leaflet from inside the pack. The leaflet will give you more information about fluphenazine, and it will also provide you with a full list of the side-effects which you could experience.
Fluphenazine long-acting injection will be given to you by a doctor or nurse. If you haven't received an injection like fluphenazine before, a small dose is usually given as a test 4-7 days before you have a full dose. This is to see how well you tolerate the injection. The injection is given into a muscle in your bottom (buttocks).
You may be asked to continue taking your currently prescribed tablets for a short while after you have had your first injection. This is because it can take a few weeks before you feel the full effect from the injection.
Treatment with fluphenazine is usually long-term so that your symptoms don't return.
Få ut det mesta av din behandling
Your treatment will require careful monitoring to make sure that you get the best possible benefit from fluphenazine. Keep your regular doctor's appointments so that you get your injections on time, and your progress can be checked. If you miss an appointment for an injection, contact your doctor to arrange for another appointment as soon as possible.
Medicines similar to fluphenazine can cause people to become more sensitive to sunlight than normal. It is recommended that you avoid strong sunlight and sunbeds, and use a sun cream with a high sun protection factor even on bright but cloudy days.
If you drink alcohol, ask your doctor for advice about drinking while you are on fluphenazine. Alcohol can increase the chance that you experience side-effects and may not be advisable for you.
Smoking can interfere with the way your body handles fluphenazine. If you either start smoking or quit smoking whilst you are having fluphenazine, please make sure that you tell your doctor. It is probable that your dose will need to be adjusted.
If you have diabetes you may need to check your blood glucose more frequently, as fluphenazine can affect the levels of sugar in your blood. Your doctor will advise you about this.
If you are having any dental treatment or an operation, tell the person carrying out the treatment that you have had a fluphenazine injection. This is important because it may interfere with the anaesthetic or painkillers you receive.
If you buy or take any 'over-the-counter' medicines, check with a pharmacist that they are suitable for you to take with fluphenazine.
Can fluphenazine long-acting injection cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the ones associated with fluphenazine. The best place to find a full list of the side-effects which can be associated with your injection, is from the manufacturer's printed information leaflet supplied with the medicine. Alternatively, you can find an example of a manufacturer's information leaflet in the reference section below. Speak with your doctor or pharmacist if any of the following continue or become troublesome.
Fluphenazine side-effects | Vad kan jag göra om jag upplever detta? |
Pain at the site of the injection | This should not last long. If the area becomes red, swollen or 'lumpy', let your doctor know |
Feeling sleepy or dizzy, blurred vision | Kör inte och använd inte verktyg eller maskiner när du är påverkad |
Torr mun | Försök tugga sockerfritt tuggummi eller suga på sockerfria karameller |
Unusual or uncontrollable muscle movements, feeling shaky | Speak with your doctor about these |
Feeling restless, movement problems | Speak with your doctor |
Huvudvärk | Drick mycket vatten och be din apotekare rekommendera en lämplig smärtstillande. Om huvudvärken fortsätter, kontakta din läkare |
Changes in weight, stuffy nose, difficulty sleeping, feeling agitated or confused, sexual problems, breast changes, menstrual problems, fast heartbeats, poor judgement or reduced mental ability, stomach upset, constipation, and difficulty passing urine | Discuss these with your doctor if any become troublesome |
Viktigt: if you experience symptoms such as muscle stiffness, a very high temperature, feeling confused or sweaty, a fast heartbeat, and urinary incontinence, you should contact your doctor immediately. These can be signs of a rare but serious condition known as neuroleptic malignant syndrome.
If you experience any other symptoms which you think may be due to the injection, speak with your doctor or pharmacist for further advice.
How to store fluphenazine long-acting injection
Förvara alla läkemedel utom räckhåll och synhåll för barn.
Förvara på en sval, torr plats, borta från direkt värme och ljus.
Viktig information om alla läkemedel
Viktig information om alla läkemedel
If you suspect that you have had an overdose of this medicine, contact the accident and emergency department of your local hospital for advice.
Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.
Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.
Om du har några frågor om denna medicin, fråga din apotekare.
Rapportera biverkningar av ett läkemedel eller vaccin
Om du upplever biverkningar kan du rapportera dem online via Yellow Card webbplats.

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Kontrollera möjliga interaktioner mellan läkemedel, kosttillskott och livsmedel innan du tar dem tillsammans.
Vanliga frågor
What is the difference between fluphenazine tablets and the long-acting injection?
Fluphenazine tablets are typically used to initially ease symptoms. Once symptoms are under control, the long-acting injection, also known as a 'depot' injection, is used for maintenance. The main advantage of the injection is that it slowly releases the medication into your body over 2-5 weeks, meaning you don't have to remember to take tablets every day.
Why is a test dose given before the full fluphenazine long-acting injection?
If you haven't received a fluphenazine injection before, a small test dose is usually administered 4-7 days prior to the full dose. This is done to assess how well your body tolerates the injection before you receive the complete treatment.
How long will I need to continue taking fluphenazine long-acting injections?
Treatment with fluphenazine is usually long-term. This is to help prevent your symptoms from returning, ensuring ongoing symptom control.
Can fluphenazine affect my blood sugar if I have diabetes?
Yes, fluphenazine can affect the levels of sugar in your blood. If you have diabetes, your doctor may advise you to check your blood glucose more frequently while on this medication.
Is it safe to get dental treatment or an operation while on fluphenazine injections?
If you are having any dental treatment or an operation, it is important to inform the person carrying out the treatment that you have had a fluphenazine injection. This is because it could potentially interact with any anaesthetics or painkillers you might receive.
Vidare läsning och referenser
- Mediciner Komplett BNF 89:e Utgåvan; Brittiska Läkarföreningen och Kungliga Farmaceutiska Sällskapet i Storbritannien, London.
Om författarenVisa fullständig biografi

Michael Stewart, MRPharmS
Ansvarig för granskning av medicinbroschyrer – Konsult, Apotekare
BPharm (Hons), MRPharmS
Michael är en apotekare som arbetar i Midlands och South Yorkshire med mer än 20 års erfarenhet av att ge råd om läkemedel och medicinska tillstånd. Han har en stark bakgrund inom vårdutbildning och har producerat och levererat utbildningskurser för apoteksteam och personal inom vårdboenden, inklusive sjuksköterskor. Han har också bidragit till apoteksrådgivande styrelser för hantering av mindre allvarliga tillstånd i samhället.
Om recensenten

Sid Dajani
Sultan Dajani tog examen vid London School of Pharmacy 1994 och blev den yngsta valda medlemmen i Royal Pharmaceutical Society-rådet sedan dess grundande 1842.
Artikelhistorik
Informationen på denna sida är skriven och granskad av kvalificerade kliniker.
Artikeln finns också på Engelska, Tyska, Spanska, Franska, Italienska, Portugisiska, Hindi, Hebreiska, Arabiska, och Svenska.
Next review due: 11 Jun 2027
12 Dec 2022 | Senaste versionen

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