Ibuprofen for pain and inflammation
Brufen, Calprofen, Nurofen
Granskad av Dr Colin Tidy, MRCGPSenast uppdaterad av Michael Stewart, MRPharmSLast updated 27 Feb 2023
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Ibuprofen is a painkiller that eases pain and reduces inflammation. It should be taken with a meal or a snack.
The most common side effects are stomach ache, indigestion, feeling sick (nausea), and being sick (vomiting).
Ibuprofen is not recommended for children who have chickenpox. Use paracetamol instead.
Speak with a doctor before taking ibuprofen if you have ever had a bad reaction to any other anti-inflammatory painkiller.
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About ibuprofen
Typ av medicin | Ett icke-steroid antiinflammatoriskt läkemedel (NSAID) |
Används för | Relief of pain, inflammation, or fever |
Also called (UK) | Anadin®, Brufen®; Calprofen®; Cuprofen®; Fenpaed®; Feminax®; Flarin®; Ibucalm®; Noubid®; Nurofen® |
Also called (USA) | Advil®; Alivio®; Aprofen®; Cedaprin®; CounterAct® IB; Dolex®; Dragon Tabs®; Flex-Prin®; Ibutab®; Motrin® IB; Probufen®; Profen® IB; Proprinal® |
Tillgänglig som | Tablets, capsules, effervescent granules, oral liquid medicine, modified-release tablets, orodispersible (melt in the mouth) tablets, chewable capsules |
What is ibuprofen used for?
Tillbaka till innehållIbuprofen is a type of anti-inflammatory painkiller (also called non-steroidal anti-inflammatory drugs (NSAIDs), or 'anti-inflammatories') that is used to treat pain and reduce inflammation (swelling).
Conditions that it is commonly used to treat include:
Dental pain.
Pain after surgical operations.
Ibuprofen can also be used to relieve cold and 'flu-like' symptoms including hög temperatur (feber). It can be taken by adults and by children over the age of 3 months.
Ibuprofen is available on prescription, and you can also buy a number of preparations which contain ibuprofen without a prescription at pharmacies and other retail outlets.
It is also available as a gel which can be applied directly to your skin to help relieve muscle and joint pain.
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How does ibuprofen work?
Tillbaka till innehållIbuprofen works by blocking the effect of natural chemicals called cyclo-oxygenase (COX) enzymes.
These enzymes help to make other chemicals in the body, called prostaglandins. Some prostaglandins are produced at sites of injury or damage, and cause pain and inflammation.
By blocking the effect of COX enzymes, fewer prostaglandins are produced, which means pain and inflammation are eased.
Side effects of ibuprofen
Tillbaka till innehållCommon side effects of ibuprofen are:
Indigestion.
Heartburn.
Magont.
Illamående.
Being sick.
Diarré.
You will find a full list of the side effects associated with ibuprofen from the manufacturer's printed information leaflet supplied with the medicine.
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How to manage ibuprofen side effects
Tillbaka till innehållThe unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common ibuprofen side effects | Vad kan jag göra om jag upplever detta? |
Indigestion, heartburn, stomach pain | Remember to take your doses with food, or with a glass of milk. If the discomfort continues, speak with your doctor |
Feeling sick or being sick, diarrhoea | Stick to simple meals. Drink plenty of liquid to replace any lost fluids |
Viktigt: if you experience any of the following less frequent but possibly serious symptoms, stop taking ibuprofen and contact your doctor for advice straightaway:
Om du har några andningssvårigheter som väsande andning eller andfåddhet.
If you have any signs of an allergic reaction such as swelling around your mouth or face, or an itchy skin rash.
If you pass blood or black stools, bring up (vomit) blood, or have severe stomach pains.
Ibuprofen may increase the risk of developing serious skin infections when used in children with chickenpox. Therefore, paracetamol is usually recommended in chickenpox and ibuprofen should not be used.
Ibuprofen does not affect your ability to drive or to use machinery.
Om du upplever några andra symtom som du tror kan bero på medicinen, tala med din läkare eller apotekare för vidare råd.
Who should not take ibuprofen?
Tillbaka till innehållSome medicines are not suitable for people with certain conditions. Before taking ibuprofen it is important that your doctor knows:
If you have ever had a stomach or duodenal ulcer, or if you have an inflammatory bowel disorder such as Crohns sjukdom or ulcerös kolit.
If you have astma or any other allergic disorder.
Om du är gravid, försöker bli gravid eller ammar.
Om du har några problem med hur din lever fungerar, eller om du har några problem med hur dina njurar fungerar.
If you have a heart condition or a problem with your blood vessels or circulation.
If you have högt blodtryck.
If you have any blood clotting problems.
Om du har högt blodsocker eller kolesterolnivåer.
Om du har en bindvävssjukdom som systemisk lupus erythematosus. Detta är ett inflammatoriskt tillstånd som också kallas lupus eller SLE.
Om du tar några andra läkemedel. Detta inkluderar alla läkemedel du tar som finns att köpa utan recept, samt växtbaserade och komplementära läkemedel.
If you have ever had an allergic reaction to any other NSAID (such as aspirin, naproxen, diclofenac, and indometacin), or to any other medicine.
How to take ibuprofen
Tillbaka till innehållBefore you take ibuprofen, read the leaflet in the pack. It explains how the medicine works and lists possible side effects.
For adults and children 12 and older, the usual dose is 200-400 mg three or four times a day if needed. If your tablets are the slow-release kind, the dose is different - they’re usually taken once or twice a day.
Different brands may have different strengths, so always check the label to make sure you’re taking the right amount
If you’re giving liquid ibuprofen to a child, the dose depends on their age. Read the bottle label carefully so you give the correct amount. The doses below are a general guide for a 100 mg/5 ml ibuprofen suspension.
3-5 months: 50 mg (2.5 ml) three times daily.
6-11 months: 50 mg (2.5 ml) three or four times daily.
1-3 years: 100 mg (5 ml) three times daily.
4-6 years: 150 mg (7.5 ml) three times daily.
7-9 years: 200 mg (10 ml) three times daily.
10-11 years: 300 mg (15 ml) three times daily.
Ibuprofen is best taken with food. This will help to protect your stomach from side effects such as matsmältningsbesvär.
If you have been prescribed a modified-release form of ibuprofen (Brufen Retard® brand), swallow the tablet or capsule whole with a glass of water. Do not crush or break the tablets.
If you have been prescribed a sachet containing ibuprofen granules (Brufen® Effervescent Granules), mix the contents of the sachet into a glass of water to make a fizzy drink. Drink it straightaway after mixing it.
If you forget a dose, take it when you remember - unless it’s almost time for your next one. If it is, just skip the missed dose and take the next one as normal. Do not take two doses at once.
Få ut det mesta av din behandling
Tillbaka till innehållYour doctor will give you the lowest dose of ibuprofen for the shortest time to help avoid side effects. If you need it long-term, they might also give you another medicine to protect your stomach.
If you bought ibuprofen yourself, only use it for a short time and stop once the pain or fever goes away.
Keep your regular check-ups with your doctor, especially if you're taking ibuprofen for a long-term problem.
If you have asthma, ibuprofen can sometimes make symptoms like wheezing or breathlessness worse. If that happens, stop taking it and see your doctor.
Some anti-inflammatory medicines, including ibuprofen, may slightly increase the risk of heart and blood vessel problems if used long-term. If you’re worried, talk to a healthcare professional. Always stick to the recommended dose.
If you buy other medicines, check with a pharmacist that they’re safe to take with ibuprofen. Don’t take ibuprofen along with any other anti-inflammatory painkillers - some cold and flu medicines contain them.
Om du ska genomgå en operation eller tandbehandling, informera den som utför behandlingen om vilka mediciner du tar.
How to store ibuprofen
Tillbaka till innehållFörvara alla läkemedel utom räckhåll och synhåll för barn.
Förvara på en sval, torr plats, borta från direkt värme och ljus.
Viktig information om alla läkemedel
Tillbaka till innehållViktig information om alla läkemedel
Ta aldrig mer än den föreskrivna dosen. Om du misstänker att du eller någon annan kan ha tagit en överdos av denna medicin, gå till akutmottagningen på ditt lokala sjukhus. Ta med behållaren, även om den är tom.
Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.
Om du har några frågor om denna medicin, fråga din apotekare.
Rapportera biverkningar av ett läkemedel eller vaccin
Om du upplever biverkningar kan du rapportera dem online via Yellow Card website.
Vanliga frågor
Tillbaka till innehållHow long does it take for ibuprofen to work?
Ibuprofen usually starts working within 20 to 30 minutes, with its full pain-relieving and anti-inflammatory effects typically felt after about 1 to 2 hours. How quickly it works can depend on your metabolism and the type of ibuprofen.
Can you take ibuprofen while pregnant?
You should avoid taking ibuprofen while pregnant, especially after 20 weeks, as it may affect the baby’s development and increase the risk of complications in later pregnancy.
Can you drink alcohol with ibuprofen?
It’s generally best to avoid alcohol while taking ibuprofen as it can increase the risk of stomach irritation, bleeding, and other side effects. However, drinking a small amount of alcohol is usually fine.
Can you take ibuprofen and paracetamol together?
Yes, ibuprofen and paracetamol can be taken together for short-term pain relief as they work differently in the body. They can also be taken alternately to maintain consistent relief.
Can you take ibuprofen with co-codamol?
Yes, you can take ibuprofen with co-codamol as they work differently to relieve pain. They can provide stronger pain control when used together. Always follow dosing instructions carefully.
How long does ibuprofen last?
The effects of ibuprofen typically last 4 to 6 hours, depending on the dose and formulation. Extended-release versions may last longer.

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Vidare läsning och referenser
- Manufacturer's PIL, Ibuprofen 200 mg and 400 mg film-coated tablets (PL 16363/0523); Aurobindo Pharma - Milpharm Ltd, The electronic Medicines Compendium. Dated June 2020.
- Manufacturer's PIL, Ibuprofen 100 mg/5 ml Oral Suspension; Pinewood Healthcare Ltd, The electronic Medicines Compendium. Dated February 2023.
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About the author

Michael Stewart, MRPharmS
Medicine Leaflet Review Manager – Contractor, Pharmacist
BPharm (Hons), MRPharmS
Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.
About the reviewerView full bio

Dr Colin Tidy, MRCGP
General Practitioner, Medical Author
MBBS, MRCGP, MRCP (Paediatrics), DCH
Dr Colin Tidy is an NHS Doctor, based in Oxfordshire.
Artikelhistorik
Informationen på denna sida är skriven och granskad av kvalificerade kliniker.
Next review due: 8 Aug 2027
27 Feb 2023 | Senaste versionen

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