Levofloxacin tablets for infection
Evoxil
Granskad av Dr Colin Tidy, MRCGPSenast uppdaterad av Michael Stewart, MRPharmSLast updated 22 May 2023
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Levofloxacin is given to treat a bacterial infection.
It is important to complete the full course of treatment. This is to prevent the infection from coming back.
The most common side effects of levofloxacin are feeling sick (nausea) and diarrhoea. They are usually mild and soon pass.
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About levofloxacin
Typ av medicin | A quinolone antibiotic |
Används för | Treating infections |
Även kallad | Evoxil® |
Tillgänglig som | Tablets, eye drops |
What is levofloxacin used for?
Tillbaka till innehållLevofloxacin is a type of antibiotic used to treat bacterial infections such as sinusitis, bröstinfektioner, urine infections, prostatitis, and some skin and soft tissue infections.
It works by killing the bacteria which are the cause of the infection.
Other antibiotics are usually prescribed in preference to levofloxacin. Levofloxacin is reserved for infections which have not improved with other antibiotic treatment. It is also used if other, more preferred, antibiotics cannot be prescribed for some reason.
Levofloxacin is also available as eye drops for the treatment of eye infections. For more information on this use see the leaflet Levofloxacin eye drops.
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Side effects of levofloxacin
Tillbaka till innehållCommon side effects of levofloxacin are:
Illamående.
Being sick.
Diarré.
Headache.
Känner dig yr.
Problems sleeping.
You will find a full list in the manufacturer's information leaflet supplied with your medicine.
The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
How to manage levofloxacin side effects
Tillbaka till innehållCommon levofloxacin side effects (these affect fewer than 1 in 10 people) | Vad kan jag göra om jag upplever detta? |
Feeling sick or being sick (vomiting) | Stick to simple foods - avoid rich or spicy meals. It may help to take the tablets after food |
Diarré | Drink plenty of water to replace lost fluids. If the diarrhoea is severe or continues to be a problem, speak with your pharmacist or doctor for advice |
Huvudvärk | Drick mycket vatten och be din apotekare rekommendera en lämplig smärtstillande. Om huvudvärken fortsätter, informera din läkare |
Känner dig yr | Do not drive and do not use tools or machines until you feel well again |
Problems sleeping | Om det är besvärligt, prata med din läkare |
Temporary changes to liver enzymes | This could be noticed if you have certain blood tests |
Viktigt: there are also a number of rare but more serious side effects which have been associated with this medicine. Speak with your doctor as soon as possible if you experience the following:
An allergic-type reaction, such as swelling around your face or mouth, a skin rash, or any difficulty breathing.
Sudden pain in the abdomen (tummy), chest or back.
Pain or inflammation in your muscles, tendons or joints (possible tendinopathy).
Any feelings of pain, burning, tingling, numbness or weakness.
Any problems with your vision or eyes, or changes to taste, smell or hearing.
Disordered thinking or thoughts about harming yourself.
Severe tiredness, depressed mood, anxiety, problems with your memory or severe problems sleeping.
If you experience any other symptoms which you think may be due to the tablets, speak with your doctor or pharmacist for advice.
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Who should not take levofloxacin tablets
Tillbaka till innehållSome medicines aren’t suitable for certain health conditions or may require extra care. Before taking levofloxacin, it is important to let your doctor know:
Om du är gravid, försöker bli gravid eller ammar.
If you are under 18 years of age.
If you have ever experienced a problem with your tendons, called tendonitis.
Om du har några problem med hur dina njurar fungerar.
If you have epilepsy or any other condition that causes fits.
If you have ever had mental health problems.
If you have a heart condition, or if you have been told you have an unusual heartbeat.
If you have aortic aneurysm or a family history of aneurysm disease.
If you have a condition causing tired and weak muscles, called myasthenia gravis.
If you know you have glucose 6-phosphate dehydrogenase (G6PD) deficiency. This is a genetic disorder which causes problems after eating foods such as fava beans.
Om du tar några andra läkemedel. Detta inkluderar alla läkemedel du tar som finns att köpa utan recept, samt växtbaserade och komplementära läkemedel.
If you have ever had an allergic reaction to any medicine, especially to another quinolone antibiotic such as norfloxacin, ofloxacin, ciprofloxacin, moxifloxacin, or nalidixic acid.
How to take levofloxacin tablets
Tillbaka till innehållRead the information leaflet in the pack before starting, as it explains levofloxacin and its possible side effects.
Take levofloxacin exactly as your doctor tells you. The usual dose is 500 mg daily, but it may be 250 mg once daily or 500 mg twice daily depending on your infection. Check the label for your correct dose.
You can take it before or after meals. If taking once a day, take it in the morning. If more than once a day, space doses about 12 hours apart.
Swallow tablets with water. You can split them along the score line if needed, but do not crush or chew.
Avoid antacids, iron, or zinc supplements for two hours before and after each dose, as they reduce how well the medicine works.
If you forget a dose, take it when you remember unless the next dose is due then skip the missed dose. Don’t take two doses at once.
Finish the full course even if you feel better, unless your doctor tells you to stop. Most courses last 7–14 days. See your doctor if you still feel unwell after finishing the treatment.
Få ut det mesta av din behandling
Tillbaka till innehållRemember to keep any routine appointments with your doctor. This is so your progress can be monitored.
Levofloxacin can make your skin more sensitive to sunlight. Use sunscreen and avoid sunbeds, especially in strong sunlight.
Check with a pharmacist before taking any other medicines. Avoid NSAID painkillers, such as ibuprofen, while on levofloxacin.
Some people develop thrush (oral or vaginal) after taking a course of antibiotics. If you think you have thrush, speak with your doctor or pharmacist for advice.
This antibiotic may stop the oral typhoid vaccine from working. If you are having any vaccinations, make sure the person treating you knows that you are taking this medicine.
Levofloxacin may make you feel light-headed and impair your ability to concentrate. Make sure your reactions are normal before you drive and before you use tools or machines.
If you have diabetes, you may need to check your blood sugar (glucose) levels more regularly, as levofloxacin can affect the levels of sugar in your blood.
How to store levofloxacin
Tillbaka till innehållFörvara alla läkemedel utom räckhåll och synhåll för barn.
Förvara på en sval, torr plats, borta från direkt värme och ljus.
Viktig information om alla läkemedel
Viktig information om alla läkemedel
Ta aldrig mer än den föreskrivna dosen. Om du misstänker att du eller någon annan kan ha tagit en överdos av denna medicin, gå till akutmottagningen på ditt lokala sjukhus. Ta med behållaren, även om den är tom.
Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.
Om du ska genomgå en operation eller någon tandbehandling, informera den som utför behandlingen om vilka mediciner du tar.
Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.
Om du har några frågor om denna medicin, fråga din apotekare.
Rapportera biverkningar av ett läkemedel eller vaccin
Om du upplever biverkningar kan du rapportera dem online via Yellow Card website.
Vanliga frågor
Tillbaka till innehållHow long does it take for levofloxacin to work?
Levofloxacin usually starts to work within a few hours, with most people noticing an improvement in their symptoms after 1-3 days. Always finish your course of treatment even if you are feeling better.
Is levofloxacin safe to take during pregnancy?
Levofloxacin is generally not recommended during pregnancy as it may affect developing cartilage and joints in the baby. Doctors usually only prescribe levofloxacin if no safer option is available and the infection is serious.
Can you drink alcohol while taking levofloxacin?
It is recommended that you avoid drinking alcohol while taking levofloxacin. Alcohol doesn't stop levofloxacin from working, but it can make side effects such as nausea, dizziness, or stomach upset worse and it may slow down your body’s recovery.
Is levofloxacin a penicillin?
No, levofloxacin is not a penicillin. It is a fluoroquinolone antibiotic, which works differently from penicillin-type antibiotics and is used to treat infections when other antibiotics may not be suitable.
What bacteria does levofloxacin kill?
Levofloxacin kills a wide range of bacteria, including both Gram-positive and Gram-negative bacteria. It is a broad-spectrum antibiotic which means it works against many different bacteria.
What should you avoid while taking levofloxacin?
When taking levofloxacin, you should avoid having dairy products at the time of dose, antacids and supplements - especially iron, calcium, and zinc - within 2 hours before or after your dose, and large amounts of alcohol.

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Vidare läsning och referenser
- Manufacturer's PIL, Levofloxacin 250 mg and 500 mg Film-coated Tablets; Ipca Laboratories UK Ltd, The electronic Medicines Compendium. Dated January 2021.
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About the authorView full bio

Michael Stewart, MRPharmS
Medicine Leaflet Review Manager – Contractor, Pharmacist
BPharm (Hons), MRPharmS
Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.
About the reviewerView full bio

Dr Colin Tidy, MRCGP
General Practitioner, Medical Author
MBBS, MRCGP, MRCP (Paediatrics), DCH
Dr Colin Tidy is an NHS Doctor, based in Oxfordshire.
Artikelhistorik
Informationen på denna sida är skriven och granskad av kvalificerade kliniker.
Next review due: 21 Nov 2027
22 May 2023 | Senaste versionen

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