Lomustine capsules
Granskad av Sid DajaniSenast uppdaterad av Michael Stewart, MRPharmSLast updated 5 aug 2024
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Lomustine will be prescribed for you by a specialist doctor. It is usually taken on one day every 6-8 weeks.
Keep your regular appointments with your doctor or hospital. You will need to have frequent blood tests.
If you think you are getting an infection or if you have a high temperature, please contact your doctor straightaway.
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About lomustine capsules
Typ av medicin | An alkylating chemotherapy medicine |
Används för | Cancer |
Även kallad | Lomustine 'Medac', CeeNU® (USA) |
Tillgänglig som | Kapslar |
Lomustine is used to treat some cancers. It is given in particular to treat Hodgkin's disease when other treatments have not proved effective. It is also prescribed for some brain, lung and skin cancers. Lomustine can be given alongside other medicines or treatments for cancer.
In cancer, certain cells in the body grow and multiply too fast. Chemotherapy medicines like lomustine work by preventing the growth and division of cells. This reduces the number of cancer cells that your body makes.
Before taking lomustine
Tillbaka till innehållSome medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking lomustine it is important that your doctor knows:
Om du är gravid eller ammar.
Om du har några problem med hur dina njurar fungerar.
If you have an infection or feel unwell.
If you have coeliac disease or wheat allergy.
If you have a rare inherited blood condition called porphyria.
Om du någonsin har haft en allergisk reaktion mot en medicin.
Om du tar några andra läkemedel. Detta inkluderar alla läkemedel du tar som finns att köpa utan recept, samt växtbaserade och komplementära läkemedel.
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How to take lomustine
Tillbaka till innehållBefore you start this treatment, read any printed information you have been given by your doctor and the printed manufacturer's leaflet from inside your pack of capsules. These will give you more information about lomustine and will provide you with a full list of the side-effects which you may experience from taking it.
Lomustine will be prescribed for you by a specialist doctor who is experienced in treating your condition. Your doctor will calculate what dose is right for you and will tell you how many capsules to take. You will also be told on which day you should take them - it is important that you take lomustine exactly as your doctor tells you to. It is usually taken on just one day every 6-8 weeks (occasionally the dose can be split over three days instead). Your dose will be printed on the label of the pack to remind you about what the doctor said to you but if you are unsure about how to take the capsules, or if you have any other concerns, you should contact your doctor or hospital clinic for advice.
If you are sick (vomiting) shortly after taking a dose, please speak with your doctor or clinic for advice on what to do.
Få ut det mesta av din behandling
Tillbaka till innehållYou must try to keep your regular appointments with your doctor or hospital. This is so your doctor can check on your progress. You will need to have regular blood tests and check-ups during your treatment with lomustine.
It is important that you do not get pregnant or father a child while you are taking lomustine. Make sure you have discussed with your doctor which types of contraception are suitable for you and your partner. Women should continue to use contraception for seven months after treatment has finished. Men should not father a child for at least 4 months after finishing treatment. If you would like to have children in the future, you should ask your doctor for advice about family planning before you begin taking lomustine. This is particularly important if you are a man, as there is a risk of reduced male fertility or sterility with lomustine treatment.
While you are taking lomustine and for six months after you have stopped the treatment, do not have any immunisations (vaccinations) without talking to your specialist doctor first. Lomustine lowers your body's resistance and there is a risk that you will get an infection from some vaccines.
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Can lomustine cause problems?
Tillbaka till innehållMedicines used to treat cancer can have a number of side-effects, some of which can be delayed for several days or weeks after taking the medicine. Most chemotherapy medicines can lower the number of white cells in your blood, which increases the risk of you getting an infection. The risk of this is commonly highest 4-6 weeks after taking lomustine. You should take precautions to reduce the risk of getting an infection - you can do this by avoiding being with people who you know have an infection. If you think you are getting a sore throat or if you have a high temperature, please let your doctor know as soon as possible so that you can get some treatment straightaway.
Your doctor will discuss with you the possibility of unwanted side-effects from your treatment with lomustine, although not everyone experiences these. The table below contains some of the side-effects associated with lomustine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. Please let your doctor know if you experience any of the following:
Lomustine side-effects | Vad kan jag göra om jag upplever detta? |
A high temperature, or symptoms of an infection | Let your doctor know about this straightaway |
Känna sig illamående (nausea) eller kräkas (vomiting), aptitlöshet | Stick to simple foods - avoid fatty or spicy meals. Let your doctor know about this, as an anti-sickness medicine may help. If you are sick (vomiting) shortly after taking a dose, please speak with your doctor or clinic for advice on what to do |
Mouth ulcers, sore mouth | Brushing your teeth 2-3 times a day with a soft toothbrush and regularly using a mouth rinse may help to prevent this. If mouth ulcers become a problem, speak with your doctor |
Feeling disorientated, confused or tired; loss of hair (occurs rarely) | If troublesome, let your doctor know |
Changes to some blood tests | Your doctor will check for these |
If you experience any other symptoms which you think may be due to the capsules, speak with your doctor or pharmacist for further advice.
How to store lomustine
Tillbaka till innehållFörvara alla läkemedel utom räckhåll och synhåll för barn.
Förvara på en sval, torr plats, borta från direkt värme och ljus.
Viktig information om alla läkemedel
Tillbaka till innehållViktig information om alla läkemedel
Ta aldrig mer än den föreskrivna dosen. Om du misstänker att du eller någon annan kan ha tagit en överdos av denna medicin, gå till akutmottagningen på ditt lokala sjukhus. Ta med behållaren, även om den är tom.
Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.
Om du ska genomgå en operation eller tandbehandling, informera den som utför behandlingen om vilka mediciner du tar.
If you buy any medicines, always check with a pharmacist that they are suitable for you to take with your prescribed medicines.
Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.
Om du har några frågor om denna medicin, fråga din apotekare.
Rapportera biverkningar av ett läkemedel eller vaccin
Om du upplever biverkningar kan du rapportera dem online via Yellow Card website.

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Vidare läsning och referenser
- Summary of Product Characteristics (SPC), information for healthcare professionals, Lomustine 'Medac' 40 mg capsules; Medac GmBH, The electronic Medicines Compendium. Dated April 2024.
- Mediciner Komplett BNF 89:e Utgåvan; Brittiska Läkarföreningen och Kungliga Farmaceutiska Sällskapet i Storbritannien, London.
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About the authorView full bio

Michael Stewart, MRPharmS
Medicine Leaflet Review Manager – Contractor, Pharmacist
BPharm (Hons), MRPharmS
Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.
About the reviewer

Sid Dajani
Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.
Artikelhistorik
Informationen på denna sida är skriven och granskad av kvalificerade kliniker.
Next review due: 1 Aug 2027
5 aug 2024 | Senaste versionen

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