Norethisterone contraceptive injection
Noristerat
Granskad av Sid DajaniSenast uppdaterad av Michael Stewart, MRPharmSSenast uppdaterad 27 Jan 2023
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Norethisterone injection is given to prevent pregnancy. It provides contraception for about eight weeks.
Read the manufacturer's information leaflet from the pack before having the injection.
The most common side-effect is irregular menstrual bleeding.
Överblick
Norethisterone injection is a short-term contraceptive similar to the natural hormone progesterone.
It prevents pregnancy mainly by stopping the release of an egg from the ovary.
The injection provides contraception for approximately eight weeks.
You will receive an information leaflet before the injection, which is given into your buttock muscle.
Your periods are likely to change, and irregular bleeding may occur.
Tell your doctor if you are pregnant, have liver problems, certain arterial diseases, or breast cancer.
About norethisterone contraceptive injection
Typ av medicin | Progestogen |
Används för | Preventivmedel |
Även kallad | Norethindrone (in US); Noristerat® |
Tillgänglig som | Injection |
Norethisterone is a progestogen, which is a female sex hormone similar to the progesterone hormone made naturally by your ovaries. It is an effective and convenient form of short-term preventivmetod. The injection will provide contraception for about eight weeks.
Norethisterone works mainly by stopping ovulation (the release of an egg from the ovary). It also changes the lining of your womb (uterus) to make it less likely that an egg would attach to it, even if an egg were to fertilise. In addition, the mucus which forms a plug in the neck of your womb (cervix) becomes thicker. This stops sperm getting through to the womb to fertilise an egg.
Before you have norethisterone contraceptive injection
Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before having Noristerat® it is important that your doctor knows:
If you think you could already be pregnant.
If you have any problems with the way your liver works.
If you have a problem with your arteries, called arterial disease.
If you have an ovarian cyst, or any vaginal bleeding other than your normal monthly period.
If you have systemic lupus erythematosus (this is an inflammatory condition, often called SLE).
If you have ever had an ectopic pregnancy or if you have developed severe itching of your skin, or yellowing of your skin or the whites of your eyes (jaundice) during a pregnancy.
If you have had breast cancer or a cancer that you have been told is dependent on a sex hormone.
If you have ever had depression.
Om du har en sällsynt ärftlig blodsjukdom som kallas porfyri.
Om du någonsin har haft en allergisk reaktion mot en medicin.
If you are taking any other medicines, including those available to buy without a prescription, as well as herbal and complementary medicines. This is because some medicines interfere with the way progestogen contraceptives work.
How norethisterone contraceptive injection is given
Before you are given the injection you will be asked to read a printed information leaflet from the manufacturer. The manufacturer's leaflet will give you important information about the injection and will provide a full list of the side-effects which you may experience from it. If you have any questions as a result of reading the leaflet, please discuss them with your doctor/nurse before you have the injection. You will be given the leaflet to take home.
You will be given the injection by your nurse or doctor. It is usually given during the first 1-5 days of a period. The norethisterone is injected slowly into a muscle in your buttock. From there, it is gradually released into your bloodstream.
Få ut det mesta av din behandling
Your periods are likely to change. Spotting, breakthrough bleeding and delayed periods may occur. Some women have irregular bleeding which can be heavier and longer than normal. Irregular bleeding can sometimes also be due to another reason (such as an infection), so let your doctor know if it happens.
Norethisterone injection provides contraception for eight weeks. It is often given as an interim measure - for example, while your partner is having a vasectomy. Make sure your doctor knows if there is any delay to your longer-term plans for contraception.
You may gain a little weight. Eating a well-balanced diet and taking regular exercise can help to keep this to a minimum.
Regularly check your breasts for any lumps or bumps. Speak with your doctor if you notice any changes.
Please note: the injection will not protect you against HIV (AIDS) or any other sexually transmitted infections.
Some medicines can reduce the effectiveness of this contraceptive. These include medicines for epilepsy, medicines to treat fungal infections, the herbal preparation St John's wort, and medicines used to treat tuberculosis (TB). Tell the doctor that you have had a progestogen contraceptive injection if you are prescribed any other medicines. If you buy any medicines 'over the counter', ask the pharmacist for advice.
Can norethisterone contraceptive injection cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with a norethisterone contraceptive injection. You will find a full list in the manufacturer's information leaflet that has been given to you. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Very common Noristerat® side-effects (these affect more than 1 in 10 women) | Vad kan jag göra om jag upplever detta? |
Spotting | If you are concerned, speak with your doctor |
Oregelbundna menstruationer | Let your doctor know if this happens |
Common Noristerat® side-effects (these affect fewer than 1 in 10 women) | Vad kan jag göra om jag upplever detta? |
Huvudvärk | Ask your pharmacist to recommend a suitable painkiller |
Känner dig illamående (nausea) | This does not usually last for long but in the meantime, stick to simple meals |
Increased weight, skin reactions, feeling dizzy | Om det är besvärligt, prata med din läkare |
If you experience any other symptoms which you think may be due to the injection, speak with your doctor or pharmacist for advice.
Viktig information om alla läkemedel
Viktig information om alla läkemedel
Om du ska genomgå en operation eller någon tandbehandling, informera den som utför behandlingen om vilka mediciner du tar eller använder.
Behåll aldrig föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.
If you have any questions about your medicines, ask your pharmacist.
Rapportera biverkningar av ett läkemedel eller vaccin
Om du upplever biverkningar kan du rapportera dem online via Yellow Card webbplats.

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Vanliga frågor
How long does the norethisterone contraceptive injection provide protection?
The norethisterone contraceptive injection provides contraception for approximately eight weeks. It is often used as a short-term measure.
Are there specific circumstances where norethisterone injection is recommended as an interim contraceptive method?
Yes, norethisterone injection is sometimes given as an interim measure. For example, it might be used while a partner is having a vasectomy, to ensure contraception during that period.
What should I do if my irregular bleeding is unusually heavy or lasts longer than normal while on norethisterone injection?
While irregular bleeding can be a side-effect, sometimes heavy or prolonged bleeding can be due to another reason, such as an infection. It's important to let your doctor know if this happens so they can investigate.
How does norethisterone injection prevent pregnancy?
Norethisterone primarily works by stopping ovulation, which is the release of an egg from the ovary. It also makes the lining of your womb less receptive to a fertilised egg and thickens the mucus in the cervix, making it harder for sperm to reach the womb.
Are there any health conditions that would prevent me from using the norethisterone contraceptive injection?
Yes, there are several conditions that might mean this injection is not suitable for you. These include problems with liver function, certain arterial diseases, if you have an ovarian cyst or any unexplained vaginal bleeding, a history of breast cancer or hormone-dependent cancer, an ectopic pregnancy, certain skin conditions during pregnancy (like severe itching or jaundice), severe depression, or a rare blood disorder called porphyria. Your doctor will assess these before giving you the injection.
Does the norethisterone injection protect against sexually transmitted infections?
No, the norethisterone injection only provides contraception. It will not protect you against HIV (AIDS) or any other sexually transmitted infections.
Vidare läsning och referenser
- Manufacturer's PIL, Noristerat® 200 mg solution for intramuscular injection; Bayer plc, The electronic Medicines Compendium. Dated June 2019.
- Mediciner Komplett BNF 89:e Utgåvan; Brittiska Läkarföreningen och Kungliga Farmaceutiska Sällskapet i Storbritannien, London.
Om författarenVisa fullständig biografi

Helen Allen, MPharm
Apotekare, Medicinsk Författare
MPharm
Helen Allen kvalificerade sig som apotekare 1979 och tillbringade 3 år som författare av läkemedelsinformationsbroschyrer för EMIS.
Om recensenten

Sid Dajani
Sultan Dajani tog examen vid London School of Pharmacy 1994 och blev den yngsta valda medlemmen i Royal Pharmaceutical Society-rådet sedan dess grundande 1842.
Artikelhistorik
Informationen på denna sida är skriven och granskad av kvalificerade kliniker.
Artikeln finns också på Engelska, Tyska, Spanska, Franska, Italienska, Portugisiska, Hindi, Hebreiska, Arabiska, och Svenska.
Next review due: 26 Jul 2027
27 Jan 2023 | Senaste versionen
20 Apr 2011 | Ursprungligen publicerad
Författad av:
Helen Allen, MPharm

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