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Norethisterone for painful or heavy periods

Primolut N, Utovlan

Norethisterone is a female hormone treatment.

The usual dose is one tablet either two or three times daily. You may be asked to take the tablets regularly each day, or just to take them on certain days of the month.

The most common side-effects are feeling bloated, feeling sick (nausea), and headache. These are generally mild in nature.

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About norethisterone

Typ av medicin

Progestogen (female hormone)

Används för

Painful or heavy periods, particularly when associated with endometriosis

Även kallad

Norethindrone (in US); Primolut N®, Utovlan®

Tillgänglig som

Tabletter

Norethisterone is a man-made form of progesterone, a naturally occurring female sex hormone. It is referred to as a progestogen and it has a number of uses. Low doses are used to prevent pregnancy, or as hormone replacement therapy (HRT). Medium-strength tablets (5 mg) such as Primolut N® and Utovlan® are used to treat heavy and painful periods particularly if they are associated with a condition called endometrios. Higher doses are used in the treatment of some female cancers, such as breast cancer.

This leaflet discusses norethisterone when it is used to treat painful or heavy periods associated with endometriosis. Endometriosis is a condition where tissue which is normally only found inside the womb (uterus), becomes 'trapped' in other parts of the body, often in the pelvic area or lower abdomen. This causes symptoms such as painful and heavy periods. Treatment aims to reduce the pain and amount of blood loss. Norethisterone can also be considered for heavy periods not associated with endometriosis, although other treatment options are more commonly prescribed for this.

There are a number of other medicine leaflets which will give you more information about norethisterone if you are taking it for contraception or as HRT. These are: Progestogen-only contraceptive tablets, Norethisterone contraceptive injection, Combined hormonal contraceptives och Oestrogen and progestogen for HRT.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking norethisterone it is important that your doctor knows:

  • Om du är gravid eller ammar.

  • If you have any problems with the way your liver works, or any kidney problems.

  • If you have heart or blood vessel problems, or if you have ever had a blood clot in an artery or vein.

  • If you have any of the following: diabetes, epilepsy, migraines, high blood pressure (hypertension), or asthma.

  • If you smoke, are overweight or have high cholesterol levels.

  • If you have ever had cancer.

  • If you have ever had a depressive illness.

  • If you have ever had yellowing of your skin or the whites of your eyes (jaundice), severe itching, or a skin condition called pemphigoid gestationis during a pregnancy.

  • If you have a rare inherited blood disorder called porphyria.

  • Om du tar några andra läkemedel. Detta inkluderar alla läkemedel du tar som finns att köpa utan recept, samt växtbaserade och komplementära läkemedel.

  • Om du någonsin har haft en allergisk reaktion mot en medicin.

Fortsätt läsa nedan

  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about norethisterone and will provide you with a full list of the side-effects which you may experience from taking it.

  • Take norethisterone exactly as your doctor tells you to. You may be asked to take the tablets regularly each day, or to take them just on certain days of your monthly cycle. This information will be printed on the label of your pack of tablets to remind you, but if you are still unsure, ask your pharmacist for further advice.

  • It is common to take one tablet three times each day, although your dose may be different to this.

  • Swallow the tablets with a drink of water. You can take norethisterone tablets either before or after meals.

  • Try to take your doses at the same times of day, as this will help you to remember to take your doses.

  • If you do forget to take a dose at your usual time, take it as soon as you remember, unless it is nearly time for your next dose in which case leave out the forgotten dose. Remember to take your next dose when it is due but do not take two doses together to make up for a forgotten dose.

  • Försök att hålla dina regelbundna möten med din läkare. Detta är så att din läkare kan följa upp din utveckling.

  • You should avoid getting pregnant, as norethisterone can affect a developing baby. Use barrier methods of contraception (such as a condom) if you have sex whilst taking norethisterone. If you need further contraceptive advice, speak with your doctor.

  • If you have diabetes you may need to check your blood glucose more frequently, as norethisterone can affect the levels of sugar in your blood. Your doctor will be able to advise you about this.

  • If you are due to have an operation or any medical treatment, tell the person carrying out the treatment that you are taking norethisterone.

Fortsätt läsa nedan

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with norethisterone. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Common norethisterone side-effects

Vad kan jag göra om jag upplever detta?

Shorter periods, no periods, breakthrough bleeding, 'spotting'

Your doctor will discuss this with you before you start treatment

Känner dig illamående (nausea)

Stick to simple meals - avoid rich and spicy foods. If you are not already doing so, try taking the tablets after a meal

Huvudvärk

Ask your pharmacist to recommend a suitable painkiller. If the headache is unusually severe or continues, speak with your doctor straightaway

Bloating, fluid retention

Om det är besvärligt, prata med din läkare

Less common norethisterone side-effects

Vad kan jag göra om jag upplever detta?

Feeling dizzy, breast tenderness, changes in weight, feeling tired or difficulty sleeping, feeling depressed, lack of interest in sex, skin reactions

Om något av dessa blir besvärligt, tala med din läkare

Viktigt: norethisterone can also have some serious side-effects, although these occur only rarely. If you experience any of the following symptoms, stop taking the tablets and contact your doctor for advice straightaway:

  • Any feeling of pain or tightness in your chest.

  • Any disturbances of your vision or hearing.

  • Any unusually severe headaches.

  • Any yellowing of your skin or the whites of your eyes (jaundice).

If you experience any other symptoms which you think may be due to the tablets, speak with your doctor or pharmacist for advice.

  • Förvara alla läkemedel utom räckhåll och synhåll för barn.

  • Förvara på en sval, torr plats, borta från direkt värme och ljus.

Viktig information om alla läkemedel

Ta aldrig mer än den föreskrivna dosen. Om du misstänker att du eller någon annan kan ha tagit en överdos av denna medicin, gå till akutmottagningen på ditt lokala sjukhus. Ta med behållaren, även om den är tom.

Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.

If you buy any medicines 'over the counter', always check with a pharmacist that they are suitable to take with your other medicines.

Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.

Om du har några frågor om denna medicin, fråga din apotekare.

Rapportera biverkningar av ett läkemedel eller vaccin

Om du upplever biverkningar kan du rapportera dem online via Yellow Card website.

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Kontrollera möjliga interaktioner mellan läkemedel, kosttillskott och livsmedel innan du tar dem tillsammans.

Vidare läsning och referenser

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Artikelhistorik

Informationen på denna sida är skriven och granskad av kvalificerade kliniker.

  • Next review due: 16 Aug 2027
  • 17 Feb 2023 | Senaste versionen

    Senast uppdaterad av

    Michael Stewart, MRPharmS

    Granskad av

    Sid Dajani
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