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Olanzapine long-acting injection

Zypadhera

Olanzapine long-acting injection will be given to you by your clinic doctor or nurse every 2-4 weeks.

The injection may cause you to feel sleepy or dizzy for a few hours afterwards.

If you miss an appointment for an injection, make another appointment as soon as possible.

There are a number of side-effects which you could experience from the treatment. If you are concerned about any, you should discuss them with your doctor.

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About olanzapine long-acting injection

Typ av medicin

An antipsychotic injection

Används för

Maintenance of symptom control in adults with schizophrenia and other similar mental health problems

Även kallad

Zypadhera® (olanzapine embonate)

Tillgänglig som

Long-acting depot injection

Olanzapine belongs to a group of medicines called antipsychotics. You will have been prescribed it to maintain symptom control of schizophrenia.

Schizophrenia is a mental health condition that causes disordered ideas, beliefs and experiences. Symptoms of schizophrenia include hearing, seeing, or sensing things that are not real, having mistaken beliefs, feeling unusually suspicious, and becoming withdrawn. Olanzapine is used to relieve the symptoms of schizophrenia and other similar mental health problems. It works on the balance of chemical substances in your brain.

Long-acting, or 'depot', injections are used once your symptoms have been eased by taking tablets. The injection slowly releases olanzapine into your body and is given either every two weeks, or every four weeks. The main advantage of a depot injection is that you do not have to remember to take tablets every day.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start having olanzapine long-acting injections, it is important that your doctor knows:

  • Om du är gravid eller ammar.

  • If you have a heart condition or blood vessel disease.

  • Om du har några problem med hur din lever fungerar, eller om du har några problem med hur dina njurar fungerar.

  • If you have prostate problems.

  • If you have any problems with your breathing.

  • If you have any of the following: epilepsi, diabetes (diabetes mellitus), depression, Parkinson's disease, raised pressure in your eye (glaucoma) or a condition which causes muscle weakness, called myasthenia gravis.

  • If you have ever had yellowing of your skin or the whites of your eyes (gulsot).

  • If you have a blood or bone marrow disorder.

  • If you are very constipated or think you may have a blockage in your bowel.

  • If you have had an allergic reaction to a medicine.

  • Om du tar eller använder några andra läkemedel. Detta inkluderar alla läkemedel du tar som finns att köpa utan recept, samt växtbaserade och komplementära läkemedel.

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  • Before you start the treatment, ask to read the manufacturer's printed information leaflet from inside the pack. The leaflet will give you more information about olanzapine, and it will also provide you with a full list of the side-effects which you could experience.

  • Olanzapine long-acting injection will be given to you in an outpatient clinic by a doctor or nurse. The injection is given into a muscle in your bottom (buttocks). As a routine, you will be asked to stay in the clinic where you can be observed for at least three hours after each injection. This is because it can make you feel tired or dizzy after it is given. You will be advised not to drive and not to use tools or machines for the remainder of the day.

  • You may be asked to continue taking your current tablets for a short while after you have had your first injection. This is because it can take a few weeks before you feel the full effect from the injection.

  • Treatment with olanzapine is usually long-term so that your symptoms don't return.

  • Your treatment will require careful monitoring to make sure that you get the best possible benefit from olanzapine. Keep your regular doctor's appointments so that you get your injections on time, and your progress can be checked. If you miss an appointment for an injection, contact the hospital to arrange for another appointment as soon as possible.

  • Olanzapine could cause your skin to become more sensitive to sunlight than normal. Avoid strong sunlight and sunbeds, and use a sun cream with a high sun protection factor even on bright but cloudy days.

  • If you drink alcohol, ask your doctor for advice about drinking while you are on olanzapine. Alcohol can increase the chance that you will experience side-effects and may not be advisable for you.

  • If you have diabetes you may need to check your blood sugar (glucose) more frequently, as olanzapine can affect the levels of sugar in your blood. Your doctor will advise you about this.

  • If you are having any dental treatment or an operation, tell the person carrying out the treatment that you have had an olanzapine injection. This is important because it may interfere with the anaesthetic you receive.

  • If you buy or take any 'over-the-counter' medicines, check with a pharmacist that they are suitable for you to take with olanzapine.

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Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the more common ones associated with olanzapine. The best place to find a full list of the side-effects which can be associated with your medicine, is from the manufacturer's printed information leaflet supplied with the medicine. Alternatively, you can find an example of a manufacturer's information leaflet in the reference section below. Speak with your doctor or pharmacist if any of the following continue or become troublesome.

Very common olanzapine side-effects (these affect more than 1 in 10 people)


Vad kan jag göra om jag upplever detta?

Feeling sleepy, tired or dizzy

Kör inte och använd inte verktyg eller maskiner när du är påverkad

Increased weight

Eat a well-balanced diet. Speak with your doctor if your weight becomes troublesome

Changes to some blood test results

Your doctor will monitor for these

Common olanzapine side-effects

(these affect fewer than 1 in 10 people)

Vad kan jag göra om jag upplever detta?

Feeling restless

Prata med din läkare om detta

Pain at the site of the injection

This should not last long. If the area becomes red, swollen or 'lumpy', let your doctor know

Torr mun

Försök tugga sockerfritt tuggummi eller suga på sockerfria karameller

Förstoppning

Drink plenty of water, and eat a well-balanced diet containing plenty of fruit, vegetables, and fibre

Unusual or uncontrollable muscle movements, shakiness

Speak with your doctor about these

Increased appetite and weight, rash, feeling hot, reduced interest in sex, erectile dysfunction, aches and pains

Discuss these with your doctor if any become troublesome

Viktigt: if you experience symptoms such as muscle stiffness, a very high temperature, feeling confused or sweaty, a fast heartbeat, and urinary incontinence, you should contact your doctor immediately. These can be signs of a rare but serious condition known as neuroleptic malignant syndrome.

If you experience any other symptoms which you think may be due to the injection, speak with your doctor or pharmacist for further advice.

Viktig information om alla läkemedel

If you suspect that you have had an overdose of this medicine, go to the accident and emergency department of your local hospital at once.

Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.

Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.

Om du har några frågor om denna medicin, fråga din apotekare.

Rapportera biverkningar av ett läkemedel eller vaccin

Om du upplever biverkningar kan du rapportera dem online via Yellow Card website.

symptom checker

Osäker på att blanda mediciner?

Kontrollera möjliga interaktioner mellan läkemedel, kosttillskott och livsmedel innan du tar dem tillsammans.

Vidare läsning och referenser

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Artikelhistorik

Informationen på denna sida är skriven och granskad av kvalificerade kliniker.

  • Next review due: 11 Jun 2027
  • 12 Dec 2022 | Senaste versionen

    Senast uppdaterad av

    Michael Stewart, MRPharmS

    Granskad av

    Sid Dajani
  • 20 Aug 2010 | Ursprungligen publicerad

    Författad av:

    Helen Allen, MPharm
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