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Tiagabin för epilepsi

Gabitril

Take your doses of tiagabine during a meal or with a snack.

You need to take tiagabine regularly. Do not stop taking it unless your doctor tells you to.

The most common side-effects are feeling sick (nausea), tired, shaky or dizzy.

Överblick

  • Tiagabine is an antiepileptic medicine for adults and children over 12 with partial seizures.

  • It works alongside other medicines to stabilise electrical activity in the brain.

  • Take tiagabine exactly as prescribed, usually with food or a snack.

  • Do not stop taking tiagabine suddenly, as this can cause problems.

  • If you have mood changes or thoughts about suicide, tell your doctor straightaway.

  • Common side effects include dizziness, shakiness, tiredness, and feeling sick.

  • If you get a severe rash or unusual bruising, contact your doctor immediately.

About tiagabine

Typ av medicin

An antiepileptic medicine

Används för

Epilepsy with partial seizures in adults or in children over 12 years of age

Även kallad

Gabitril®

Tillgänglig som

Tabletter

Having epilepsy means that you have had more than one otherwise unexplained fit, or seizure. A seizure is a short episode of symptoms caused by a burst of abnormal electrical activity in your brain. With partial seizures (also called focal seizures), the burst of electrical activity is in one part of your brain and therefore you tend to have localised or 'focal' symptoms. Because different parts of the brain control different functions, your symptoms will depend on which part of your brain is affected. Partial seizures can sometimes develop into seizures which affect all of your brain. These are called secondary generalised seizures. Symptoms that may occur during a seizure can affect your muscles, sensations, behaviour, emotions, consciousness, or a combination of these.

The seizures can be prevented in most people by suitable antiepileptic medication. Tiagabine works alongside other antiepileptic medicines to stabilise the electrical activity of your brain. It does this by increasing the amount of a chemical in your brain, called gamma-aminobutyric acid (GABA). This helps to prevent the seizures from occurring.

Before taking tiagabine

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking tiagabine it is important that your doctor knows:

  • Om du är gravid, försöker bli gravid eller ammar.

  • If you have problems with the way your liver works.

  • If you have a rare inherited blood condition called porphyria.

  • Om du tar några andra läkemedel. Detta inkluderar alla läkemedel du tar som finns att köpa utan recept, samt växtbaserade och komplementära läkemedel.

  • Om du någonsin har haft en allergisk reaktion mot en medicin.

How to take tiagabine

  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about tiagabine and will provide you with a full list of the side-effects which you may experience from taking it.

  • Take tiagabine exactly as your doctor tells you to. Your dose will be printed on the label of the pack to remind you about what the doctor said. There are several different strengths of tiagabine tablets. It is usual to start treatment on a low dose, and then for the dose to be increased gradually to a regular maintenance dose. You will begin by taking one or two doses each day, and this may gradually increase to two or three doses a day as your dose becomes fixed.

  • It is important you try to take your doses at the same times of day, each day. Having a routine will help you to remember to take your doses regularly.

  • Swallow the tablet with a drink of water. You should take tiagabine with, or straight after, a meal or a snack.

  • If you forget to take a dose, take it as soon as you remember. If when you remember, it is nearly time for your next dose then take your next dose when it is due but leave out the missed dose. Do not take two doses together to make up for a forgotten dose.

Få ut det mesta av din behandling

  • When you first start a new treatment for epilepsy there may be a change in the number or type of seizures you experience. Your doctor will advise you about this.

  • Försök att hålla dina regelbundna möten med din läkare. Detta är så att din läkare kan följa upp din utveckling.

  • While you are being treated for epilepsy there is a small risk that you may develop mood changes, distressing thoughts and feelings about suicide. If this happens, you must tell your doctor about it straightaway.

  • People with epilepsy must stop driving at first. Your doctor will advise you about when it may be possible for you to start driving again. This will usually be after a year free of seizures.

  • If you drink alcohol, ask your doctor for advice. Your doctor may advise you not to drink alcohol while you are on this medicine.

  • Different formulations of some antiepileptic medicines can act in a slightly different way in your body. Because of this, your doctor may recommend that you continue to take tiagabine from the same manufacturer each time you obtain a new supply. If so, each time you collect a prescription, check to make sure your supply looks the same and that the name is the same. If you are unsure, or if you have any questions about your prescription, please ask your pharmacist to advise you.

  • If you buy any medicines, check with a pharmacist that they are suitable for you to take with your antiepileptic medication.

  • Many antiepileptic medicines can harm an unborn child. If you are a woman, make sure you have discussed with your doctor which types of contraception are suitable for you and your partner. If you want to have a family, discuss this with your doctor so that you can be given advice from a specialist before you become pregnant.

  • You need to take tiagabine regularly every day. Do not stop taking it unless your doctor tells you to stop. Stopping treatment suddenly can cause problems and your doctor will want you to reduce your dose gradually if this becomes necessary.

Can tiagabine cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with tiagabine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Very common tiagabine side-effects (these affect more than 1 in 10 people)

Vad kan jag göra om jag upplever detta?

Feeling dizzy, shaky, tired or nervous

If any of these happen, do not drive and do not use tools or machines

Känner dig illamående (nausea)

Stick to simple meals - avoid rich and spicy food

Common tiagabine side-effects (these affect fewer than 1 in 10 people)

Vad kan jag göra om jag upplever detta?

Stomach discomfort, diarrhoea

Stick to simple meals and drink plenty of water to replace any lost fluids

Dimsyn

Do not drive and do not use tools or machines. If it continues, let your doctor know, as you may need to have an eye assessment

Feeling unsteady, lack of concentration, mood changes, difficulties sleeping, speech difficulties, and muscle twitches

If any of these become troublesome, let your doctor know

Viktigt: your doctor will discuss with you the possibility that tiagabine can cause more severe reactions in a few people. Although these occur less commonly than the symptoms listed above, it is important that you contact your doctor straightaway if you experience any of the following:

  • A severe rash.

  • Any unusual bruising.

Om du upplever några andra symtom som du tror kan bero på tabletterna, tala med din läkare eller apotekare för vidare råd.

How to store tiagabine

  • Förvara alla läkemedel utom räckhåll och synhåll för barn.

  • Store in a cool, dry place, away from direct heat and light. Keep the tablets in their original bottle until you are ready to take them. This is because they absorb moisture from the air and there is a drying agent in the bottle to help prevent this.

Viktig information om alla läkemedel

Viktig information om alla läkemedel

Ta aldrig mer än den föreskrivna dosen. Om du misstänker att du eller någon annan kan ha tagit en överdos av denna medicin, gå till akutmottagningen på ditt lokala sjukhus. Ta med behållaren, även om den är tom.

Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.

Om du ska genomgå en operation eller tandbehandling, informera den som utför behandlingen om vilka mediciner du tar.

Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.

Om du har några frågor om denna medicin, fråga din apotekare.

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Rapportera misstänkta biverkningar av läkemedel, vacciner, e-cigaretter, medicintekniska händelser, defekta eller förfalskade (falska) produkter till Läkemedelsverket för att säkerställa säker och effektiv användning.

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Vanliga frågor

What should I do if I experience mood changes, distressing thoughts, or feelings about suicide while taking tiagabine?

If you develop mood changes, distressing thoughts, or feelings about suicide, you must tell your doctor about it straight away. There is a small risk of these effects when starting epilepsy treatment.

How long will I need to take tiagabine?

You need to take tiagabine regularly every day. Do not stop taking it unless your doctor tells you to do so. Suddenly stopping treatment can cause problems, and your doctor will likely want you to reduce your dose gradually if it becomes necessary to stop.

Are there any specific storage instructions for tiagabine?

Yes, store tiagabine in a cool, dry place, away from direct heat and light. Keep the tablets in their original bottle until you are ready to take them because they absorb moisture from the air, and the bottle contains a drying agent to prevent this.

What should I do if I experience a severe rash or unusual bruising?

Although less common, tiagabine can cause more severe reactions in a few people. If you experience a severe rash or any unusual bruising, you must contact your doctor straight away.

Can I give my tiagabine tablets to someone else if they have similar symptoms?

No, this medicine is for you only. Never give it to other people, even if their condition appears to be the same as yours.

What is the purpose of the manufacturer's printed information leaflet inside the tiagabine pack?

The manufacturer's printed information leaflet provides more details about tiagabine, including a full list of all possible side-effects you might experience. It's important to read it before you start treatment.

Vidare läsning och referenser

Om författarenVisa fullständig biografi

Författarbild

Michael Stewart, MRPharmS

Ansvarig för granskning av medicinbroschyrer – Konsult, Apotekare

BPharm (Hons), MRPharmS

Michael är en apotekare som arbetar i Midlands och South Yorkshire med mer än 20 års erfarenhet av att ge råd om läkemedel och medicinska tillstånd. Han har en stark bakgrund inom vårdutbildning och har producerat och levererat utbildningskurser för apoteksteam och personal inom vårdboenden, inklusive sjuksköterskor. Han har också bidragit till apoteksrådgivande styrelser för hantering av mindre allvarliga tillstånd i samhället.

Om recensenten

Författarbild

Sid Dajani

Sultan Dajani tog examen vid London School of Pharmacy 1994 och blev den yngsta valda medlemmen i Royal Pharmaceutical Society-rådet sedan dess grundande 1842.

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Informationen på denna sida är skriven och granskad av kvalificerade kliniker.

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