Tolterodine
Detrusitol, Neditol
Granskad av Sid DajaniSenast uppdaterad av Michael Stewart, MRPharmSSenast uppdaterad 20 Jul 2024
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Tolterodine will help to ease urinary symptoms such as urge, frequency and incontinence.
The most common side-effects are a dry mouth and headache. It can also affect your vision or cause you to feel tired. If this happens to you, do not drive and do not use tools or machines while you are affected.
Överblick
Tolterodine is a medicine used to treat urinary symptoms like urgency, frequency, and incontinence.
It works by stopping sudden bladder muscle contractions and increasing the bladder's capacity.
It can also be prescribed for children over 5 years old for bedwetting.
Take tolterodine exactly as your doctor tells you, either as tablets twice daily or capsules once daily.
Common side-effects include dry mouth, headache, blurred vision, and constipation.
If side-effects are troublesome or persistent, speak with your doctor.
About tolterodine
Typ av medicin | An antimuscarinic medicine |
Används för | Urinary symptoms such as frequency, urgency and incontinence |
Även kallad | Detrusitol®; Blerone® XL; Mariosea® XL; Neditol® XL; Preblacon® XL; Tolthen® XL; Tolterma® XL; |
Tillgänglig som | Tablets and prolonged-release capsules |
Tolterodine is prescribed for people who have difficulty controlling their bladders. It is given to treat symptoms such as urgency, frequency and incontinence. Urinary urgency occurs when you have a sudden and urgent need to pass urine. If you need to take more trips to the toilet than normal, this is called urinary frequency. If you leak urine before you go to the toilet, this is called incontinence.
There are several different causes of these urinary symptoms, including weakened pelvic floor muscles and problems causing your bladder muscles to contract too much or too early. Sometimes the cause of the symptoms is unknown.
Tolterodine works by stopping sudden bladder muscle contractions and increasing the volume of urine that your bladder can hold. This helps to control the release of urine and eases your symptoms.
In addition to these uses, tolterodine can also be prescribed on the advice of a specialist for older children (over 5 years of age) to help reduce bedwetting caused by an overactive bladder. If your child has been prescribed it for this reason, please ask your child's specialist if you require any further information about the medicine.
Before taking tolterodine
Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking tolterodine it is important that your doctor knows:
Om du är gravid eller ammar.
If you have a heart condition, such as an unusual heart rhythm, problems with the blood vessels in your heart, or heart failure.
If you have any problems with the way your liver works or with the way your kidneys work.
If you have any problems with your prostate gland.
If you have any of the following conditions: increased eye pressure (called glaucoma); hiatus hernia; an overactive thyroid gland; high blood pressure; a condition causing muscle weakness, called myasthenia gravis.
If you have a condition which could cause a blockage in your stomach, bowel or urinary tract.
Om du någonsin har haft en allergisk reaktion mot en medicin.
Om du tar några andra läkemedel. Detta inkluderar alla läkemedel du tar som finns att köpa utan recept, samt växtbaserade och komplementära läkemedel.
How to take tolterodine
Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about tolterodine and will provide you with a full list of the side-effects which you may experience from taking it.
Take tolterodine exactly as your doctor tells you to. Your dose will be printed on the label of the pack to remind you about what the doctor said to you.
If you have been given tablets, you will be asked to take one tablet twice daily. There are two strengths of tablet: 1 mg and 2 mg. It is usual to start by taking the 2 mg strength tablet. Your doctor may recommend the lower 1 mg strength tablet for you if side-effects become troublesome.
If you have been given capsules, you will be asked to take one capsule daily. There are two strengths of capsule available: 2 mg and 4 mg. It is usual to take the 4 mg strength capsule. The capsules have been specially made to release tolterodine evenly over the day, so it is important that you swallow the capsule whole - do not chew it before you swallow.
You can take tolterodine either before or after meals. Swallow your doses with a drink of water.
Try to take your doses at the same times of day each day, as this will help you to remember to take them regularly. If you do forget to take a dose, take it as soon as you remember unless it is nearly time for your next dose, in which case leave out the missed dose. Do not take two doses together to make up for a forgotten dose.
Få ut det mesta av din behandling
Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress and review your treatment.
Drinks containing caffeine (for example, tea, coffee, hot chocolate and cola) may make your symptoms worse. This is because caffeine increases urine flow (it is a natural diuretic) and will make you want to pass urine. If you drink a lot of caffeine-containing drinks, consider switching to decaffeinated alternatives.
Try to maintain a normal life as much as possible with regard to drinking and visiting the toilet. However, drinking late at night may mean your sleep is disturbed by the desire to get up and go to the toilet, so you may want to avoid drinking too much during the evening.
Your doctor may suggest that you do some pelvic floor exercises to strengthen the muscles around the underside of your bladder. These can help to improve your symptoms.
If you buy any medicines or herbal remedies, always check with a pharmacist that they are suitable to take with tolterodine. Some medicines (particularly antihistamines) can increase the chance that you will experience unwanted effects such as a dry mouth, constipation and feeling sleepy.
Can tolterodine cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the common ones associated with tolterodine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Very common tolterodine side-effects (these affect more than 1 in 10 people) | Vad kan jag göra om jag upplever detta? |
Torr mun | Försök tugga sockerfritt tuggummi eller suga på sockerfria karameller |
Huvudvärk | Ensure you are drinking the recommended amount of water each day. Ask your pharmacist to recommend a suitable painkiller. If the headaches continue, let your doctor know |
Common tolterodine side-effects (these affect fewer than 1 in 10 people) | Vad kan jag göra om jag upplever detta? |
Blurred vision, feeling sleepy, tired or dizzy | Do not drive and do not use tools or machines |
Indigestion, tummy (abdominal) pain, feeling sick (nausea) | Eat simple meals - avoid rich or spicy foods |
Förstoppning | Try to eat a well-balanced diet and drink several glasses of water each day |
Diarré | Drick mycket vatten för att ersätta de förlorade vätskorna |
Chest infections, skin tingling, a fast heartbeat, dry skin, discomfort passing urine, putting on weight, dry eyes | Discuss these with your doctor if any become troublesome |
If you experience any other symptoms which you think may be due to tolterodine, please speak with your doctor or pharmacist for further advice.
How to store tolterodine
Förvara alla läkemedel utom räckhåll och synhåll för barn.
Förvara på en sval, torr plats, borta från direkt värme och ljus.
Viktig information om alla läkemedel
Viktig information om alla läkemedel
Ta aldrig mer än den föreskrivna dosen. Om du misstänker att du eller någon annan kan ha tagit en överdos av denna medicin, gå till akutmottagningen på ditt lokala sjukhus. Ta med behållaren, även om den är tom.
Om du ska genomgå en operation eller tandbehandling, informera den som utför behandlingen om vilka mediciner du tar.
Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.
Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.
Om du har några frågor om denna medicin, fråga din apotekare.
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Vanliga frågor
Can tolterodine interact with other medications I'm taking?
Yes, it's important to tell your doctor about all other medicines you are taking, including those available without a prescription, as well as herbal and complementary medicines. Some medicines can increase the chance of experiencing unwanted side-effects like dry mouth, constipation, and drowsiness when taken with tolterodine.
How long will I need to take tolterodine?
The article does not specify a typical duration for tolterodine treatment. You should keep your regular appointments with your doctor so they can monitor your progress and review your treatment, which would include determining how long you need to take the medication.
Is there anything I can do to help tolterodine work better or to reduce my symptoms naturally?
Yes, there are several things you can try. Consider switching to decaffeinated alternatives for drinks like tea, coffee, hot chocolate, and cola, as caffeine can worsen symptoms by increasing urine flow. Also, avoid drinking too much late at night to prevent sleep disturbance caused by needing to urinate. Your doctor might also recommend pelvic floor exercises to strengthen the muscles around your bladder, which can help improve your symptoms.
What are the active ingredients in the Blerone® XL, Mariosea® XL, Neditol® XL, Preblacon® XL, and Tolthen® XL medications mentioned?
All the brand names listed, including Blerone® XL, Mariosea® XL, Neditol® XL, Preblacon® XL, and Tolthen® XL, are alternative names for tolterodine. Therefore, tolterodine is the active ingredient in all of them.
Vidare läsning och referenser
- Manufacturer's PIL, Detrusitol® 1 mg and 2 mg film-coated tablets; Upjohn UK Ltd (Pfizer Ltd), The electronic Medicines Compendium. Dated February 2023.
- Manufacturer's PIL, Detrusitol XL® 4 mg capsules; Upjohn UK Ltd (Pfizer Ltd), The electronic Medicines Compendium. Dated March 2023.
- Mediciner Komplett BNF 89:e Utgåvan; Brittiska Läkarföreningen och Kungliga Farmaceutiska Sällskapet i Storbritannien, London.
Om författarenVisa fullständig biografi

Michael Stewart, MRPharmS
Ansvarig för granskning av medicinbroschyrer – Konsult, Apotekare
BPharm (Hons), MRPharmS
Michael är en apotekare som arbetar i Midlands och South Yorkshire med mer än 20 års erfarenhet av att ge råd om läkemedel och medicinska tillstånd. Han har en stark bakgrund inom vårdutbildning och har producerat och levererat utbildningskurser för apoteksteam och personal inom vårdboenden, inklusive sjuksköterskor. Han har också bidragit till apoteksrådgivande styrelser för hantering av mindre allvarliga tillstånd i samhället.
Om recensenten

Sid Dajani
Sultan Dajani tog examen vid London School of Pharmacy 1994 och blev den yngsta valda medlemmen i Royal Pharmaceutical Society-rådet sedan dess grundande 1842.
Artikelhistorik
Informationen på denna sida är skriven och granskad av kvalificerade kliniker.
Artikeln finns också på Engelska, Tyska, Spanska, Franska, Italienska, Portugisiska, Hindi, Hebreiska, Arabiska, och Svenska.
Next review due: 24 Jul 2027
20 Jul 2024 | Senaste versionen

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