Tolterodine
Detrusitol, Neditol
Granskad av Sid DajaniSenast uppdaterad av Michael Stewart, MRPharmSLast updated 20 Jul 2024
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Tolterodine will help to ease urinary symptoms such as urge, frequency and incontinence.
The most common side-effects are a dry mouth and headache. It can also affect your vision or cause you to feel tired. If this happens to you, do not drive and do not use tools or machines while you are affected.
At a glance
Tolterodine is a medicine for urinary symptoms like urgency, frequency, and incontinence.
It comes as tablets or prolonged-release capsules.
Tolterodine works by stopping sudden bladder muscle contractions.
Take it exactly as your doctor tells you, either before or after meals.
Common side-effects include dry mouth and headache.
Do not drive or use machines if you experience blurred vision, sleepiness, tiredness or dizziness.
Speak to your doctor or pharmacist if any side-effects continue or become troublesome.
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About tolterodine
Typ av medicin | An antimuscarinic medicine |
Används för | Urinary symptoms such as frequency, urgency and incontinence |
Även kallad | Detrusitol®; Blerone® XL; Mariosea® XL; Neditol® XL; Preblacon® XL; Tolthen® XL; Tolterma® XL; |
Tillgänglig som | Tablets and prolonged-release capsules |
Tolterodine is prescribed for people who have difficulty controlling their bladders. It is given to treat symptoms such as urgency, frequency and incontinence. Urinary urgency occurs when you have a sudden and urgent need to pass urine. If you need to take more trips to the toilet than normal, this is called urinary frequency. If you leak urine before you go to the toilet, this is called incontinence.
There are several different causes of these urinary symptoms, including weakened pelvic floor muscles and problems causing your bladder muscles to contract too much or too early. Sometimes the cause of the symptoms is unknown.
Tolterodine works by stopping sudden bladder muscle contractions and increasing the volume of urine that your bladder can hold. This helps to control the release of urine and eases your symptoms.
In addition to these uses, tolterodine can also be prescribed on the advice of a specialist for older children (over 5 years of age) to help reduce bedwetting caused by an overactive bladder. If your child has been prescribed it for this reason, please ask your child's specialist if you require any further information about the medicine.
Before taking tolterodine
Tillbaka till innehållSome medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking tolterodine it is important that your doctor knows:
Om du är gravid eller ammar.
If you have a heart condition, such as an unusual heart rhythm, problems with the blood vessels in your heart, or heart failure.
If you have any problems with the way your liver works or with the way your kidneys work.
If you have any problems with your prostate gland.
If you have any of the following conditions: increased eye pressure (called glaucoma); hiatus hernia; an overactive thyroid gland; high blood pressure; a condition causing muscle weakness, called myasthenia gravis.
If you have a condition which could cause a blockage in your stomach, bowel or urinary tract.
Om du någonsin har haft en allergisk reaktion mot en medicin.
Om du tar några andra läkemedel. Detta inkluderar alla läkemedel du tar som finns att köpa utan recept, samt växtbaserade och komplementära läkemedel.
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How to take tolterodine
Tillbaka till innehållBefore you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about tolterodine and will provide you with a full list of the side-effects which you may experience from taking it.
Take tolterodine exactly as your doctor tells you to. Your dose will be printed on the label of the pack to remind you about what the doctor said to you.
If you have been given tablets, you will be asked to take one tablet twice daily. There are two strengths of tablet: 1 mg and 2 mg. It is usual to start by taking the 2 mg strength tablet. Your doctor may recommend the lower 1 mg strength tablet for you if side-effects become troublesome.
If you have been given capsules, you will be asked to take one capsule daily. There are two strengths of capsule available: 2 mg and 4 mg. It is usual to take the 4 mg strength capsule. The capsules have been specially made to release tolterodine evenly over the day, so it is important that you swallow the capsule whole - do not chew it before you swallow.
You can take tolterodine either before or after meals. Swallow your doses with a drink of water.
Try to take your doses at the same times of day each day, as this will help you to remember to take them regularly. If you do forget to take a dose, take it as soon as you remember unless it is nearly time for your next dose, in which case leave out the missed dose. Do not take two doses together to make up for a forgotten dose.
Få ut det mesta av din behandling
Tillbaka till innehållTry to keep your regular appointments with your doctor. This is so your doctor can check on your progress and review your treatment.
Drinks containing caffeine (for example, tea, coffee, hot chocolate and cola) may make your symptoms worse. This is because caffeine increases urine flow (it is a natural diuretic) and will make you want to pass urine. If you drink a lot of caffeine-containing drinks, consider switching to decaffeinated alternatives.
Try to maintain a normal life as much as possible with regard to drinking and visiting the toilet. However, drinking late at night may mean your sleep is disturbed by the desire to get up and go to the toilet, so you may want to avoid drinking too much during the evening.
Your doctor may suggest that you do some pelvic floor exercises to strengthen the muscles around the underside of your bladder. These can help to improve your symptoms.
If you buy any medicines or herbal remedies, always check with a pharmacist that they are suitable to take with tolterodine. Some medicines (particularly antihistamines) can increase the chance that you will experience unwanted effects such as a dry mouth, constipation and feeling sleepy.
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Can tolterodine cause problems?
Tillbaka till innehållAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the common ones associated with tolterodine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Very common tolterodine side-effects (these affect more than 1 in 10 people) | Vad kan jag göra om jag upplever detta? |
Torr mun | Försök tugga sockerfritt tuggummi eller suga på sockerfria karameller |
Huvudvärk | Ensure you are drinking the recommended amount of water each day. Ask your pharmacist to recommend a suitable painkiller. If the headaches continue, let your doctor know |
Common tolterodine side-effects (these affect fewer than 1 in 10 people) | Vad kan jag göra om jag upplever detta? |
Blurred vision, feeling sleepy, tired or dizzy | Do not drive and do not use tools or machines |
Indigestion, tummy (abdominal) pain, feeling sick (nausea) | Eat simple meals - avoid rich or spicy foods |
Förstoppning | Try to eat a well-balanced diet and drink several glasses of water each day |
Diarré | Drick mycket vatten för att ersätta de förlorade vätskorna |
Chest infections, skin tingling, a fast heartbeat, dry skin, discomfort passing urine, putting on weight, dry eyes | Discuss these with your doctor if any become troublesome |
If you experience any other symptoms which you think may be due to tolterodine, please speak with your doctor or pharmacist for further advice.
How to store tolterodine
Tillbaka till innehållFörvara alla läkemedel utom räckhåll och synhåll för barn.
Förvara på en sval, torr plats, borta från direkt värme och ljus.
Viktig information om alla läkemedel
Tillbaka till innehållViktig information om alla läkemedel
Ta aldrig mer än den föreskrivna dosen. Om du misstänker att du eller någon annan kan ha tagit en överdos av denna medicin, gå till akutmottagningen på ditt lokala sjukhus. Ta med behållaren, även om den är tom.
Om du ska genomgå en operation eller tandbehandling, informera den som utför behandlingen om vilka mediciner du tar.
Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.
Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.
Om du har några frågor om denna medicin, fråga din apotekare.
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Om du upplever biverkningar kan du rapportera dem online via Yellow Card website.

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Vanliga frågor
What is the primary purpose of tolterodine?
Tolterodine is prescribed to help people control their bladders. It is used to treat symptoms like a sudden and urgent need to pass urine (urgency), needing to go to the toilet more often than normal (frequency), and leaking urine before reaching the toilet (incontinence).
Are there different forms of tolterodine available?
Yes, tolterodine is available as both tablets and prolonged-release capsules. Tablets are typically taken twice daily, while the prolonged-release capsules are taken once daily and should be swallowed whole to ensure the medicine is released evenly over the day.
Can children take tolterodine?
Tolterodine can be prescribed for older children (over 5 years of age) to help reduce bedwetting caused by an overactive bladder. This is done on the advice of a specialist.
What should I avoid drinking while taking tolterodine?
Drinks containing caffeine, such as tea, coffee, hot chocolate, and cola, may worsen your urinary symptoms because caffeine is a diuretic and increases urine flow. Consider switching to decaffeinated alternatives if you consume a lot of these drinks.
What should I do if I forget to take a dose of tolterodine?
If you forget to take a dose, take it as soon as you remember. However, if it is almost time for your next dose, you should skip the missed dose. Do not take two doses together to compensate for a forgotten one.
Are there any specific lifestyle changes I can make to help my treatment?
Beyond taking your medicine, you can try to maintain a normal routine with drinking and toilet visits, but avoid excessive drinking late at night to prevent sleep disturbances. Your doctor might also recommend pelvic floor exercises to strengthen bladder muscles, which can help improve symptoms. Additionally, discuss any over-the-counter or herbal remedies with a pharmacist, as some can interact with tolterodine.
What should I do if I experience a dry mouth from tolterodine?
Dry mouth is a very common side-effect of tolterodine. To help relieve it, you can try chewing sugar-free gum or sucking on sugar-free sweets.
Vidare läsning och referenser
- Manufacturer's PIL, Detrusitol® 1 mg and 2 mg film-coated tablets; Upjohn UK Ltd (Pfizer Ltd), The electronic Medicines Compendium. Dated February 2023.
- Manufacturer's PIL, Detrusitol XL® 4 mg capsules; Upjohn UK Ltd (Pfizer Ltd), The electronic Medicines Compendium. Dated March 2023.
- Mediciner Komplett BNF 89:e Utgåvan; Brittiska Läkarföreningen och Kungliga Farmaceutiska Sällskapet i Storbritannien, London.
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About the authorView full bio

Michael Stewart, MRPharmS
Medicine Leaflet Review Manager – Contractor, Pharmacist
BPharm (Hons), MRPharmS
Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.
About the reviewer

Sid Dajani
Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.
Artikelhistorik
Informationen på denna sida är skriven och granskad av kvalificerade kliniker.
Next review due: 24 Jul 2027
20 Jul 2024 | Senaste versionen

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