Trihexyphenidyl
Granskad av Sid DajaniSenast uppdaterad av Michael Stewart, MRPharmSSenast uppdaterad 7 Aug 2023
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Trihexyphenidyl is usually prescribed to relieve unwanted side-effects caused by certain other medicines.
When starting your treatment your doctor will give you a small dose and will then gradually increase your dose every few days. This helps your body adjust to the medicine and reduces the risk of side-effects. Take it exactly as your doctor tells you to.
The most common side-effects are a dry mouth, constipation, blurred vision, and feeling sick (nausea).
About trihexyphenidyl
Typ av medicin | An antimuscarinic medicine |
Används för | Unwanted 'extrapyramidal side-effects' caused by some medicines |
Tillgänglig som | Tabletter och flytande medicin för oral användning |
Trihexyphenidyl is an antimuscarinic medicine. It is prescribed for people who have unwanted movement disorders as a side-effect of taking certain other medicines, such as some antipsykotiska läkemedel. These movement disorders are often referred to as 'extrapyramidal side-effects' and include things like uncontrolled face and body movements, tremor, and restlessness.
Trihexyphenidyl can also be given to relieve muscle stiffness in people with Parkinsons sjukdom, although other medicines are generally preferred.
Before taking trihexyphenidyl
Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking trihexyphenidyl it is important that your doctor knows:
Om du är gravid, försöker bli gravid eller ammar.
Om du har några problem med hur din lever fungerar, eller hur dina njurar fungerar.
Om du har några problem med hjärtat eller blodkärlen.
If you have prostate problems, or if you have been experiencing difficulty passing urine.
If you have been constipated for more than a week.
If you have a condition which causes raised pressure in your eyes, such as glaucoma.
Om du har högt blodtryck.
Om du har ett tillstånd som orsakar muskelsvaghet, kallat myasthenia gravis.
If you have ever had a mental health problem called psychosis.
Om du tar några andra läkemedel. Detta inkluderar alla läkemedel du tar som finns att köpa utan recept, samt växtbaserade och komplementära läkemedel.
Om du någonsin har haft en allergisk reaktion mot en medicin.
How to take trihexyphenidyl
Before you start this treatment, read the manufacturer's printed information leaflet from inside your pack. It will give you more information about trihexyphenidyl and will provide you with a full list of the side-effects which you may experience from taking it.
Take trihexyphenidyl exactly as your doctor tells you to. When starting your treatment your doctor will give you a small dose (usually 1 mg daily) and will then gradually increase your dose every few days. Carefully follow the directions your doctor gives to you. Once you are on a full dose, it is likely that you will be taking three doses of trihexyphenidyl a day, although it may be more or less often than this.
Trihexyphenidyl tablets should be taken with or just after a meal. Try to take your doses at the same times of day each day, as this will help you to remember to take your doses regularly.
Om du glömmer att ta en dos, ta den så snart du kommer ihåg det, såvida det inte är dags för nästa dos. Om det snart är dags för nästa dos, ta den när det är dags men hoppa över den glömda dosen. Ta inte två doser samtidigt för att kompensera för en missad dos.
Få ut det mesta av din behandling
Försök att hålla dina regelbundna möten med din läkare. Detta är så att din läkare kan följa upp din utveckling.
If you buy any medicines, check with a pharmacist that they are safe to take with trihexyphenidyl. Some antihistamines and some strong painkillers can interfere with trihexyphenidyl and increase the risk of side-effects.
If you are having an operation or any dental treatment, tell the person carrying out the treatment that you are taking trihexyphenidyl.
If you have been taking trihexyphenidyl for some time, do not stop taking it without speaking with your doctor first. Stopping suddenly can cause problems so your doctor will want to reduce your dose gradually if this becomes necessary.
Ask your doctor for advice before drinking alcohol while you are on trihexyphenidyl. Your doctor may recommend you do not drink alcohol because it increases the possibility of side-effects such as feeling sleepy.
Can trihexyphenidyl cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with trihexyphenidyl. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects usually improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Vanlig trihexyphenidyl side-effects (these affect fewer than 1 in 10 people) | Vad kan jag göra om jag upplever detta? |
Torr mun | Try chewing sugar-free gum or sucking sugar-free sweets. If a dry mouth is still troublesome, speak with your pharmacist for advice |
Känna sig illamående (nausea) eller kräkas (vomiting) | Håll dig till enkel mat - undvik rika eller kryddiga måltider |
Blurred vision, feeling dizzy | Om detta händer, kör inte och använd inte verktyg eller maskiner |
Förstoppning | Försök att äta en välbalanserad kost och dricka flera glas vatten varje dag |
Difficulty passing urine | If this becomes troublesome, speak with your doctor for advice |
Om du upplever några andra symtom som du tror kan bero på medicinen, tala med din läkare eller apotekare för vidare råd.
How to store trihexyphenidyl
Förvara alla läkemedel utom räckhåll och synhåll för barn.
Förvara på en sval, torr plats, borta från direkt värme och ljus.
Viktig information om alla läkemedel
Viktig information om alla läkemedel
Ta aldrig mer än den föreskrivna dosen. Om du misstänker att du eller någon annan kan ha tagit en överdos av denna medicin, gå till akutmottagningen på ditt lokala sjukhus. Ta med behållaren, även om den är tom.
Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.
Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.
Om du har några frågor om denna medicin, fråga din apotekare.
Rapportera biverkningar av ett läkemedel eller vaccin
Om du upplever biverkningar kan du rapportera dem online via Yellow Card webbplats.
Vanliga frågor
What kind of effects can I expect from an antimuscarinic medicine like trihexyphenidyl?
Trihexyphenidyl is an antimuscarinic medicine. It works to help reduce unwanted movement disorders, specifically those known as 'extrapyramidal side-effects'. These can include uncontrolled movements of the face and body, tremor, and restlessness. It can also help relieve muscle stiffness, such as in Parkinson's disease.
Are there any specific activities I should avoid while taking trihexyphenidyl besides driving?
Yes, if you experience blurred vision or dizziness, you should not use tools or machines. Additionally, it's recommended to ask your doctor for advice before drinking alcohol as it can increase the possibility of side-effects like feeling sleepy.
What should I do if I've been on trihexyphenidyl for a while and want to stop taking it?
If you have been taking trihexyphenidyl for some time, it's important not to stop taking it suddenly. Stopping abruptly can cause problems. You should speak with your doctor first, as they will likely want to reduce your dose gradually if it becomes necessary to stop the medication.
How should I manage a dry mouth caused by trihexyphenidyl?
If you experience a dry mouth, you can try chewing sugar-free gum or sucking sugar-free sweets. If the dry mouth remains troublesome, you should speak with your pharmacist for further advice.
What should I do if I feel dizzy or my vision becomes blurry while taking this medication?
If you experience blurred vision or feel dizzy while taking trihexyphenidyl, it is important that you do not drive, operate tools, or use machines. These side-effects usually improve as your body adjusts to the medicine, but if they continue or become troublesome, speak with your doctor or pharmacist.
Can I take other medications, including over-the-counter ones, while on trihexyphenidyl?
Before taking any other medicines, including those you can buy without a prescription, as well as herbal and complementary medicines, you should check with a pharmacist to ensure they are safe to take with trihexyphenidyl. Specifically, some antihistamines and strong painkillers can interact with trihexyphenidyl and increase the risk of side-effects.
What's the best way to remember to take my doses regularly?
To help you remember your doses, try to take trihexyphenidyl at the same times each day. The tablets should be taken with or just after a meal.
Vidare läsning och referenser
- Manufacturer's PIL, Trihexyphenidyl 2 mg Tablets; Genus Pharmaceuticals, The electronic Medicines Compendium. Dated July 2016.
Om recensenten

Sid Dajani
Sultan Dajani tog examen vid London School of Pharmacy 1994 och blev den yngsta valda medlemmen i Royal Pharmaceutical Society-rådet sedan dess grundande 1842.
Artikelhistorik
Artikeln finns också på Engelska, Tyska, Spanska, Franska, Italienska, Portugisiska, Hindi, Hebreiska, Arabiska, och Svenska.
Next review due: 6 Feb 2028
7 Aug 2023 | Senaste versionen
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