Can I take Atorvastatin and Candesartan together?

You can take atorvastatin och candesartan together as they do not interfere with each other's absorption or excretion.

Atorvastatin and candesartan are processed by different pathways in the body. Atorvastatin is primarily broken down by a liver enzyme called CYP3A4, while candesartan is not significantly processed by this system.

How to take atorvastatin and candesartan safely

• It is usually best to take them at the same time each day to help you remember.

• Always inform your doctor if you experience unusual muscle pain or weakness, which is a general side effect of statins, but not caused by taking it with candesartan.

Graviditet

You must not take candesartan if you are pregnant or planning to become pregnant, as it can cause serious harm or death to an unborn baby. Use effective contraception while taking it.

You must not take atorvastatin if you are pregnant or planning to become pregnant, as it can harm the developing baby. Use effective contraception while taking it.

Muscle disorders (rhabdomyolysis) - atorvastatin

You must report any unexplained muscle pain, tenderness, or weakness to your doctor immediately. In rare cases, this can lead to serious kidney damage.

Grapefruit juice

Grapefruit juice contains compounds that can increase the level of atorvastatin in your blood. This can increase your risk of side effects, such as muscle pain or damage.

Avoid drinking large quantities (more than 1.2 litres daily), though it is safest to avoid it altogether while taking this medicine.

Alkohol

While there is no direct interaction, drinking large amounts of alcohol can increase the risk of liver problems with atorvastatin.

For candesartan, alcohol can increase the blood-pressure-lowering effect, which may make you feel dizzy or lightheaded. It is best to keep your alcohol intake within the recommended low-risk guidelines.

Salt substitutes (potassium-based)

Candesartan can increase the levels of potassium in your blood. Many 'low-sodium' salt substitutes contain potassium chloride.

Using these while taking candesartan can lead to dangerously high potassium levels (hyperkalaemia). Check with your pharmacist before using salt substitutes.

Taking multiple medicines? Our Interaktionskontroll för läkemedel helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Ansvarsfriskrivning

Denna information är endast avsedd för allmän utbildning och bör inte användas som en ersättning för professionell medicinsk rådgivning. Rådfråga alltid din läkare, apotekare eller annan kvalificerad vårdpersonal innan du fattar beslut om dina mediciner. Individuella omständigheter kan variera, och endast en vårdpersonal som känner till din medicinska historia kan ge personlig vägledning.