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Can I take Codeine and Morphine together?

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Taking codeine and morphine together significantly increases the risk of serious side effects, including extreme sleepiness, dizziness, and dangerous breathing problems. Because both drugs are strong painkillers from the same family (opioids), they 'stack' on top of each other, which can lead to an accidental overdose.

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Varför detta händer

Both codeine and morphine work by attaching to the same receptors in the brain and spinal cord to block pain. Additionally, the body naturally converts a portion of codeine into morphine after you swallow it. Taking both means you are essentially taking a double dose of morphine, which can overwhelm the central nervous system.

You should not take codeine and morphine together unless specifically instructed and closely monitored by a specialist. If you have been prescribed both, speak to your doctor or pharmacist immediately to clarify the dosing schedule. Seek emergency medical help if you experience extreme drowsiness, confusion, shallow breathing, or difficulty waking up.

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Breathing problems (e.g. COPD, severe asthma)

These medicines can dangerously slow your breathing. Do not take them if you have severe lung disease or are having an asthma attack.

Alcohol consumption

Drinking alcohol while taking these medicines significantly increases the risk of life-threatening breathing difficulties and extreme sleepiness.

Addiction and Dependency

Codeine contains an opioid which can cause addiction if used for more than 3 days. Long-term use can lead to withdrawal symptoms when you stop.

Breastfeeding

Do not take codeine while breastfeeding. It passes into breast milk and can cause life-threatening breathing problems or extreme sleepiness in your baby.

Alkohol

It is best to avoid or strictly limit alcohol while taking these medicines. Combining alcohol with strong painkillers like codeine or morphine significantly increases the risk of dangerous side effects, such as extreme sleepiness, breathing difficulties, and a potentially fatal overdose.

Grapefruit juice

Grapefruit juice can interfere with how your body processes codeine. This may make the medicine less effective at relieving pain or, in some cases, increase the risk of side effects. It is best to avoid drinking large amounts of grapefruit juice while taking codeine.

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Taking multiple medicines? Our Interaktionskontroll för läkemedel helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Ansvarsfriskrivning

Denna information är endast avsedd för allmän utbildning och bör inte användas som en ersättning för professionell medicinsk rådgivning. Rådfråga alltid din läkare, apotekare eller annan kvalificerad vårdpersonal innan du fattar beslut om dina mediciner. Individuella omständigheter kan variera, och endast en vårdpersonal som känner till din medicinska historia kan ge personlig vägledning.

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Artikelhistorik

Informationen på denna sida är skriven och granskad av kvalificerade kliniker.

  • 24 jan 2026 | Ursprungligen publicerad
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