Can I take Fluanxol and Prozac together?
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Ursprungligen publicerad 25 jan 2026
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Taking these two medicines together can increase the risk of a serious heart rhythm problem called QT prolongation. It can also lead to an excessive buildup of fluanxol in your body, which may cause severe side effects like uncontrollable muscle movements, stiffness, or extreme restlessness.
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Varför detta händer
Prozac (fluoxetine) blocks the liver enzymes (specifically CYP2D6) that your body uses to break down Fluanxol (flupentixol). This causes the levels of Fluanxol in your blood to rise significantly. Additionally, both drugs have a side effect that can affect the electrical activity of your heart.
Vad du bör göra
Tillbaka till innehållYou must speak to your doctor before taking these together. They may need to lower your dose of Fluanxol or perform an ECG (heart trace) to check your heart rhythm. Seek immediate medical help if you feel dizzy, faint, or notice a fast or pounding heartbeat.
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Viktiga försiktighetsåtgärder
Tillbaka till innehållIncreased Suicidal Thoughts
In the first few weeks of treatment, Prozac can increase thoughts of self-harm or suicide, particularly in patients under 25. You must be closely monitored by family or a doctor during this time.
Serotonin Syndrome
Taking these medicines together increases the risk of a life-threatening condition called serotonin syndrome. Seek urgent medical help if you experience high fever, agitation, confusion, or severe muscle twitching.
Parkinson's disease
Fluanxol can significantly worsen the symptoms of Parkinson's disease and should generally be avoided.
Heart rhythm disorders (Long QT syndrome)
Fluanxol can affect your heart rhythm. You must tell your doctor if you have a history of heart rhythm problems or are taking other medicines that affect the heart.
Bipolär sjukdom
Prozac can trigger a manic episode (periods of high energy, racing thoughts, and impulsive behaviour) if you have undiagnosed bipolar disorder.
Low sodium levels (hyponatremia)
Prozac can cause a serious drop in blood sodium levels, especially in older adults or those taking diuretics. Seek medical help if you experience severe confusion, weakness, or seizures.
Varningar för mat och dryck
Tillbaka till innehållAlkohol
It is best to avoid or strictly limit alcohol when taking these medicines. Alcohol can significantly increase the sedative effects of Fluanxol and Prozac, making you feel very drowsy, dizzy, or uncoordinated. Combining alcohol with these medications also increases the risk of experiencing more severe side effects.
Caffeine (Coffee, Tea, Energy Drinks)
Caffeine can interfere with how Fluanxol works. High amounts of caffeine may reduce the effectiveness of the medicine or worsen symptoms of restlessness and anxiety. Try to keep your caffeine intake consistent and moderate.
Prozac can sometimes increase the effects of caffeine in your body. This may lead to feeling jittery, anxious, or having difficulty sleeping. If you notice these effects, you should limit your intake of caffeinated drinks.
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Användning av andra läkemedel
Tillbaka till innehållTaking multiple medicines? Our Interaktionskontroll för läkemedel helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Ansvarsfriskrivning
Denna information är endast avsedd för allmän utbildning och bör inte användas som en ersättning för professionell medicinsk rådgivning. Rådfråga alltid din läkare, apotekare eller annan kvalificerad vårdpersonal innan du fattar beslut om dina mediciner. Individuella omständigheter kan variera, och endast en vårdpersonal som känner till din medicinska historia kan ge personlig vägledning.
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Informationen på denna sida är skriven och granskad av kvalificerade kliniker.
25 jan 2026 | Ursprungligen publicerad

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