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Can I take Ibuprofen and Diclofenac together?

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Taking ibuprofen and diclofenac together significantly increases your risk of serious side effects, particularly stomach ulcers, internal bleeding, and kidney problems. Because they both belong to the same family of medicines, taking them together is like taking a double dose of the same type of drug.

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Varför detta händer

Both ibuprofen and diclofenac are Non-Steroidal Anti-Inflammatory Drugs (NSAIDs). They work by blocking enzymes (COX-1 and COX-2) that produce chemicals called prostaglandins. While prostaglandins cause pain and inflammation, they also protect the lining of your stomach and keep your kidneys working properly. By blocking these enzymes twice over, you lose that vital protection, leading to a much higher risk of damage to your digestive system and kidneys.

Do not take these two medicines together. If you find that one is not providing enough pain relief, speak to your doctor or pharmacist. They may suggest a different type of painkiller that is safe to take alongside an NSAID, such as paracetamol. If you have already taken both and experience severe stomach pain, black tarry stools, or vomit that looks like coffee grounds, seek medical help immediately.

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Astma

Do not take these medicines if you have asthma and have ever experienced wheezing, breathlessness, or a skin rash after taking aspirin or other NSAIDs, as they can trigger a life-threatening asthma attack.

Stomach ulcers or bleeding

Avoid these medicines if you have a history of stomach ulcers or gastrointestinal bleeding. They significantly increase the risk of serious stomach irritation and internal bleeding.

Pregnancy (Third Trimester)

Do not take these medicines if you are more than 28 weeks pregnant. They can cause serious heart and kidney problems in the unborn baby and may lead to complications during delivery.

Alkohol

Drinking alcohol while taking NSAIDs like diclofenac or ibuprofen can increase the risk of stomach irritation and bleeding. It is best to limit alcohol intake or avoid it entirely if you have a history of stomach issues.

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Taking multiple medicines? Our Interaktionskontroll för läkemedel helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Ansvarsfriskrivning

Denna information är endast avsedd för allmän utbildning och bör inte användas som en ersättning för professionell medicinsk rådgivning. Rådfråga alltid din läkare, apotekare eller annan kvalificerad vårdpersonal innan du fattar beslut om dina mediciner. Individuella omständigheter kan variera, och endast en vårdpersonal som känner till din medicinska historia kan ge personlig vägledning.

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Artikelhistorik

Informationen på denna sida är skriven och granskad av kvalificerade kliniker.

  • 25 jan 2026 | Ursprungligen publicerad
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