Can I take Indapamide and Vitamin C together?

Why this happens

Indapamide is a diuretic (water tablet) used to lower blood pressure, while vitamin C is a water-soluble vitamin. They are processed by the body through different pathways and do not interfere with each other's absorption, metabolism, or effectiveness.

What you should do

You can continue to take both as prescribed or recommended. As with any supplement, it is best to stick to the recommended daily allowance of vitamin C unless your doctor has advised otherwise.

Important precautions

Sulphonamide allergy

Do not take indapamide if you have a known allergy to sulphonamide medicines (such as certain antibiotics), as you may have a similar allergic reaction to this medicine.

Low potassium (hypokalaemia)

Indapamide can significantly lower your blood potassium levels. You must have regular blood tests to monitor this, especially if you experience muscle weakness, cramps, or an irregular heartbeat.

Kidney stones (oxalate)

High doses of Vitamin C can increase the risk of developing kidney stones. Avoid supplements if you have a history of calcium oxalate stones or severe kidney disease.

G6PD deficiency

If you have glucose-6-phosphate dehydrogenase (G6PD) deficiency, high doses of vitamin C can cause your red blood cells to break down (haemolysis).

Haemochromatosis

Vitamin C increases the absorption of iron from your food. If you have an iron-overload disorder like haemochromatosis, you should avoid high-dose supplements.

Food and drink warnings

Alcohol

Drinking alcohol while taking indapamide can increase the blood-pressure-lowering effect of the medicine. This may make you feel dizzy, lightheaded, or faint, especially when standing up quickly. It is best to keep your alcohol intake within recommended limits and see how the medicine affects you before drinking.

Salt (Sodium)

Eating a diet very high in salt can make indapamide less effective at lowering your blood pressure. Try to avoid adding extra salt to your food.

Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.