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Can I take Alogliptin and Metformin together?

Guide för läkemedelsinteraktioner

Taking alogliptin and metformin together is generally safe and very common. However, because both medicines work to lower your blood sugar, there is a slightly higher risk of your blood sugar dropping too low (hypoglycaemia). This is more likely if you are also taking other diabetes medicines like insulin or a sulphonylurea.

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Varför detta händer

Both drugs work in different ways to lower blood glucose. Alogliptin helps the body release more insulin after eating, while metformin reduces the amount of sugar the liver produces and helps the body use its own insulin better. Together, they have an 'additive' effect, meaning they work as a team to control blood sugar more effectively than either drug alone.

You should continue taking both medicines as prescribed by your doctor. It is important to learn the signs of low blood sugar (such as feeling shaky, sweaty, hungry, or dizzy) and always carry a fast-acting sugar source, like glucose tablets or a sugary drink. If you frequently experience symptoms of low blood sugar, speak to your doctor as they may need to adjust your doses.

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Lactic acidosis

Stop taking metformin and seek urgent medical help if you experience severe vomiting, diarrhoea, or dehydration. This medicine can cause a rare but life-threatening build-up of acid in the blood if you become severely unwell or have kidney problems.

Pankreatit

Stop taking alogliptin and see a doctor immediately if you develop severe and persistent stomach pain, which may reach through to your back. This can be a sign of an inflamed pancreas.

Contrast X-rays/Scans

You must tell your doctor you take metformin if you are having an X-ray or scan involving an injection of 'contrast' dye. You will need to stop taking metformin for 48 hours to prevent sudden kidney damage.

Alkohol

Drinking alcohol while taking metformin can increase the risk of a rare but serious condition called lactic acidosis. It can also cause your blood sugar levels to drop too low (hypoglycaemia). You should avoid excessive alcohol consumption and binge drinking.

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Taking multiple medicines? Our Interaktionskontroll för läkemedel helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Ansvarsfriskrivning

Denna information är endast avsedd för allmän utbildning och bör inte användas som en ersättning för professionell medicinsk rådgivning. Rådfråga alltid din läkare, apotekare eller annan kvalificerad vårdpersonal innan du fattar beslut om dina mediciner. Individuella omständigheter kan variera, och endast en vårdpersonal som känner till din medicinska historia kan ge personlig vägledning.

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Artikelhistorik

Informationen på denna sida är skriven och granskad av kvalificerade kliniker.

  • 25 jan 2026 | Ursprungligen publicerad
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