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Can I take Amlodipine and Bisoprolol together?

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Taking these two medicines together can cause your blood pressure to drop lower than usual or your heart rate to become very slow. This might make you feel dizzy, lightheaded, faint, or unusually tired.

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Varför detta händer

Both medicines work to lower blood pressure and slow the heart rate, but they do it in different ways. Amlodipine relaxes your blood vessels, while bisoprolol slows down the heart's contractions. When used together, their effects add up (an additive effect), which can sometimes lower your heart rate or blood pressure too much.

It is common for doctors to prescribe these together, but you should be monitored closely. When you first start this combination or if your dose is increased, take extra care when standing up from a sitting or lying position. If you feel very dizzy, experience a slow pulse, or feel like you might faint, contact your doctor. Your doctor may want to check your blood pressure and heart rate regularly.

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Asthma or Chronic Obstructive Pulmonary Disease (COPD)

Bisoprolol can cause narrowing of the airways, which may trigger a severe asthma attack or worsen breathing difficulties. It should generally be avoided if you have a history of asthma.

Diabetes

Bisoprolol can mask the warning signs of low blood sugar (hypoglycaemia), such as a fast heartbeat or tremors. You must monitor your blood sugar more closely.

Stopping treatment suddenly

Do not stop taking these medicines abruptly, especially bisoprolol. Doing so can cause a rapid rise in blood pressure or worsen chest pain (angina). Your dose must be reduced gradually under medical supervision.

Grapefruit juice

Grapefruit juice can increase the amount of amlodipine in your blood, which may cause your blood pressure to drop too low and increase the risk of side effects like headaches or swollen ankles. Avoid drinking large amounts of grapefruit juice.

Alkohol

Alcohol can increase the blood-pressure-lowering effect of these medicines, which may make you feel dizzy, lightheaded, or sleepy, especially when you first start taking them or when your dose is increased. It is best to keep your alcohol intake within recommended limits and see how the medicine affects you.

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Taking multiple medicines? Our Interaktionskontroll för läkemedel helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Ansvarsfriskrivning

Denna information är endast avsedd för allmän utbildning och bör inte användas som en ersättning för professionell medicinsk rådgivning. Rådfråga alltid din läkare, apotekare eller annan kvalificerad vårdpersonal innan du fattar beslut om dina mediciner. Individuella omständigheter kan variera, och endast en vårdpersonal som känner till din medicinska historia kan ge personlig vägledning.

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Artikelhistorik

Informationen på denna sida är skriven och granskad av kvalificerade kliniker.

  • 25 jan 2026 | Ursprungligen publicerad
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