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Can I take Aspirin and Naproxen together?

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Taking aspirin and naproxen together significantly increases your risk of developing stomach ulcers, internal bleeding, and kidney problems. Additionally, naproxen can interfere with aspirin's ability to protect your heart, making the aspirin less effective if you are taking it to prevent a heart attack or stroke.

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Varför detta händer

Both drugs belong to the same family (NSAIDs) and work by blocking enzymes called COX-1 and COX-2. When used together, they have an 'additive' effect on the stomach lining, making it much more vulnerable to damage. Furthermore, naproxen can physically block the spot where aspirin needs to attach to your blood cells (platelets), preventing aspirin from thinning the blood properly.

You should not take these two medicines together unless specifically instructed and monitored by your doctor. If you require pain relief while taking aspirin, paracetamol is generally a safer alternative. If your doctor has prescribed both, watch for signs of stomach bleeding, such as black tarry stools, coughing up blood, or severe stomach pain.

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Astma

Do not take these medicines if you have asthma that is worsened by aspirin or other non-steroidal anti-inflammatory drugs (NSAIDs), as they can trigger a life-threatening asthma attack.

Stomach ulcers or bleeding

These medicines significantly increase the risk of stomach ulcers and internal bleeding. Avoid them if you have a history of stomach ulcers or are taking other blood-thinning medications.

Pregnancy (third trimester)

Do not take these medicines if you are more than 28 weeks pregnant, as they can cause serious heart and kidney problems in the unborn baby and complications during delivery.

Alkohol

Drinking alcohol while taking these medicines increases the risk of irritation and bleeding in your stomach and intestines. It is best to limit or avoid alcohol while taking these medications, especially if you take them regularly.

Caffeine

Aspirin can increase the effects of caffeine. Additionally, both aspirin and caffeine can irritate the stomach lining, so consuming large amounts of caffeine (coffee, tea, energy drinks) while taking aspirin may increase your risk of indigestion or stomach upset.

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Taking multiple medicines? Our Interaktionskontroll för läkemedel helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Ansvarsfriskrivning

Denna information är endast avsedd för allmän utbildning och bör inte användas som en ersättning för professionell medicinsk rådgivning. Rådfråga alltid din läkare, apotekare eller annan kvalificerad vårdpersonal innan du fattar beslut om dina mediciner. Individuella omständigheter kan variera, och endast en vårdpersonal som känner till din medicinska historia kan ge personlig vägledning.

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Artikelhistorik

Informationen på denna sida är skriven och granskad av kvalificerade kliniker.

  • 25 jan 2026 | Ursprungligen publicerad
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