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Can I take Aspirin and Nustendi together?

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Taking aspirin with Nustendi (which contains bempedoic acid and ezetimibe) may slightly increase the levels of bempedoic acid in your blood. Additionally, if you are taking high doses of aspirin (over 325mg daily), there is a theoretical risk that it could interfere with how bempedoic acid works to lower your cholesterol.

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Varför detta händer

Aspirin and bempedoic acid (one of the active ingredients in Nustendi) are both processed by the same pathway in the kidneys (OAT3 transporter). Aspirin may compete with bempedoic acid, potentially slowing down its removal from the body or blocking its effectiveness at very high doses.

For most people taking low-dose 'baby' aspirin (75mg to 100mg) for heart protection, this interaction is unlikely to be clinically significant. You can continue taking both, but ensure your doctor knows you are using them. If you take high-dose aspirin for pain or inflammation, consult your doctor as they may prefer an alternative painkiller.

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Astma

Do not take aspirin if you have asthma that is worsened by aspirin or other non-steroidal anti-inflammatory drugs (NSAIDs), as it can trigger a severe or life-threatening asthma attack.

Gout

Both of these medicines can increase levels of uric acid in your blood, which may trigger a gout attack or worsen existing gout. Seek medical advice if you experience sudden joint pain or swelling.

Pregnancy (third trimester)

You must not take aspirin during the last 3 months of pregnancy as it can cause serious heart and kidney problems in the unborn baby and increase the risk of bleeding during delivery.

Grapefruit juice

While Nustendi itself does not have a direct interaction with grapefruit juice, it is often prescribed alongside statins (like simvastatin or atorvastatin). If you are taking a statin in addition to Nustendi, you should avoid drinking large amounts of grapefruit juice as it can increase the level of the statin in your blood, raising the risk of side effects.

Alkohol

You should limit or avoid alcohol while taking aspirin. Both aspirin and alcohol can irritate the lining of your stomach. Combining them significantly increases the risk of stomach irritation, inflammation, and stomach bleeds.

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Taking multiple medicines? Our Interaktionskontroll för läkemedel helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Ansvarsfriskrivning

Denna information är endast avsedd för allmän utbildning och bör inte användas som en ersättning för professionell medicinsk rådgivning. Rådfråga alltid din läkare, apotekare eller annan kvalificerad vårdpersonal innan du fattar beslut om dina mediciner. Individuella omständigheter kan variera, och endast en vårdpersonal som känner till din medicinska historia kan ge personlig vägledning.

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Artikelhistorik

Informationen på denna sida är skriven och granskad av kvalificerade kliniker.

  • 24 jan 2026 | Ursprungligen publicerad
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