Can I take Chaga and Cordyceps together?
Drug interaction guide
Originally published 25 Jan 2026
Meets Patient’s editorial guidelines
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Taking chaga and cordyceps together may increase the risk of bruising or bleeding. Both supplements can also lower blood sugar levels, which could lead to symptoms of low blood sugar (hypoglycaemia) such as dizziness or shakiness.
Why this happens
Both chaga and cordyceps have 'anti-platelet' effects, meaning they slow down blood clotting. When used together, this effect is additive. Additionally, both fungi can mimic or enhance the effects of insulin, leading to a combined lowering of blood glucose.
What you should do
It is generally safe for healthy individuals to take these together in moderate amounts, but you should use caution. If you are scheduled for surgery, stop taking both at least two weeks beforehand. If you take medication for diabetes or blood-thinning drugs (like warfarin or aspirin), speak to your doctor before combining these supplements.
Important precautions
Kidney disease or history of kidney stones
Chaga is extremely high in oxalates, which can cause permanent kidney damage or acute kidney failure, especially in those with existing renal issues.
Diabetes
Chaga may significantly lower blood sugar levels, increasing the risk of hypoglycaemia (dangerously low blood sugar) if you are taking insulin or other diabetes medications.
Autoimmune diseases (e.g., Lupus, MS, Rheumatoid Arthritis)
These mushrooms can stimulate the immune system, which may worsen symptoms of autoimmune conditions or interfere with immunosuppressant medications.
Bleeding disorders or upcoming surgery
Both mushrooms have significant anti-platelet effects and can increase the risk of bruising and bleeding; they must be stopped at least 2 weeks before any planned surgery.
Food and drink warnings
Alcohol
Chaga contains high levels of oxalates. Combining it with alcohol may increase the risk of kidney stones or kidney stress, as both substances can affect renal function. Use with caution.
Caffeine
Cordyceps may have mild stimulant properties and can interact with adenosine receptors. Combining it with caffeine (coffee, tea, energy drinks) may increase heart rate, jitteriness, or palpitations in sensitive individuals.
Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
Article also available in English, German, Spanish, French, Italian, Portuguese, Hindi, Hebrew, Arabic, and Swedish.
25 Jan 2026 | Originally published
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