Can I take Fluanxol and Wellbutrin together?

Varför detta händer

Both Fluanxol (flupentixol) and Wellbutrin (bupropion) lower the 'seizure threshold', meaning they make it easier for a seizure to occur. Additionally, Wellbutrin blocks the liver enzyme (CYP2D6) that breaks down Fluanxol, which can cause Fluanxol to build up to higher, potentially toxic levels in your body.

You must speak to your doctor before taking these two medicines together. They may need to adjust your doses or choose an alternative treatment. If you are prescribed both, seek medical help immediately if you experience a seizure, extreme shakiness, or severe agitation.

Seizure disorders or epilepsy

Wellbutrin significantly increases the risk of having a seizure. You must not take it if you have a history of epilepsy, an eating disorder (bulimia or anorexia), or if you are undergoing sudden withdrawal from alcohol or sedatives.

Parkinson's disease

Fluanxol can significantly worsen the symptoms of Parkinson's disease and should generally be avoided.

Heart rhythm disorders (Long QT syndrome)

Fluanxol can affect your heart rhythm. You must tell your doctor if you have a history of heart rhythm problems or are taking other medicines that affect the heart.

Bipolär sjukdom

These medicines can trigger a switch from depression to mania or rapid cycling in people with bipolar disorder. Monitor closely for racing thoughts, extreme energy, or impulsive behaviour.

Alkohol

You should avoid or strictly limit alcohol while taking these medicines. Alcohol can increase the sedative effects of Fluanxol, making you very drowsy. More importantly, both Wellbutrin and alcohol (or alcohol withdrawal) can lower the seizure threshold; combining them significantly increases the risk of having a fit (seizure).

Caffeine (Coffee, Tea, Energy Drinks)

Caffeine can interfere with how Fluanxol works. High amounts of caffeine may reduce the effectiveness of the medicine or worsen symptoms of restlessness and anxiety. Try to keep your caffeine intake consistent and moderate.

Wellbutrin is a stimulant. Consuming high amounts of caffeine can increase the risk of side effects such as anxiety, tremors, palpitations, and insomnia. It may also further increase the risk of seizures.

Fettrika måltider

If you are taking the modified-release version of bupropion, taking it with a very high-fat meal can increase the amount of medicine absorbed into your bloodstream, which may increase the risk of side effects. It is best to be consistent in how you take it.

Taking multiple medicines? Our Interaktionskontroll för läkemedel helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Ansvarsfriskrivning

Denna information är endast avsedd för allmän utbildning och bör inte användas som en ersättning för professionell medicinsk rådgivning. Rådfråga alltid din läkare, apotekare eller annan kvalificerad vårdpersonal innan du fattar beslut om dina mediciner. Individuella omständigheter kan variera, och endast en vårdpersonal som känner till din medicinska historia kan ge personlig vägledning.