Can I take Lansoprazole and Tramadol together?
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Ursprungligen publicerad 25 jan 2026
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There is no direct harmful interaction between lansoprazole and tramadol. However, lansoprazole reduces stomach acid, which can occasionally change how quickly some tablets dissolve, though this is not usually a problem for tramadol. Additionally, both medications can sometimes cause side effects like dizziness or sleepiness, which might be slightly more noticeable when taken together.
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Varför detta händer
Lansoprazole is a proton pump inhibitor (PPI) that reduces gastric acid. While it can alter the absorption of pH-dependent drugs, tramadol absorption is not significantly affected. Both drugs are processed by the liver (CYP enzymes), but they do not significantly interfere with each other's metabolism.
Vad du bör göra
Tillbaka till innehållIt is generally safe to take these two medicines together. If you feel particularly dizzy or sleepy, avoid driving or operating machinery. Always follow the dosage instructions provided by your doctor or pharmacist.
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Viktiga försiktighetsåtgärder
Tillbaka till innehållEpilepsy or history of seizures
Tramadol can increase the risk of having a seizure, especially if you are already prone to them or are taking certain antidepressants.
Asthma or breathing problems
Tramadol can cause dangerous breathing difficulties. You must not take it if you have severe asthma or significant breathing problems.
Severe diarrhoea
Lansoprazole can increase your risk of serious bowel infections. If you develop severe or persistent watery diarrhoea, or a fever, contact your doctor immediately and do not take anti-diarrhoeal medicine.
Lupus (SLE) or skin reactions
Contact your doctor if you develop a skin rash, especially in areas exposed to the sun, as lansoprazole can cause a rare but serious autoimmune skin reaction.
Varningar för mat och dryck
Tillbaka till innehållAlkohol
It is best to avoid or strictly limit alcohol while taking lansoprazole. Alcohol increases the amount of acid your stomach produces, which can make your symptoms worse and counteract the effects of the medicine.
It is best to avoid or strictly limit alcohol while taking tramadol. Combining alcohol with tramadol significantly increases the risk of dangerous side effects, such as extreme sleepiness, breathing difficulties, and loss of consciousness.
Food (Timing)
Lansoprazole works best if you take it at least 30 minutes before food. Taking it with or after food can make it less effective at reducing stomach acid.
Caffeine (Coffee, Tea, Energy Drinks)
Lansoprazole is often prescribed for acid reflux. Caffeine can trigger or worsen reflux symptoms by relaxing the muscle at the base of the food pipe, which may make your medicine less effective at managing your symptoms.
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Användning av andra läkemedel
Tillbaka till innehållTaking multiple medicines? Our Interaktionskontroll för läkemedel helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Ansvarsfriskrivning
Denna information är endast avsedd för allmän utbildning och bör inte användas som en ersättning för professionell medicinsk rådgivning. Rådfråga alltid din läkare, apotekare eller annan kvalificerad vårdpersonal innan du fattar beslut om dina mediciner. Individuella omständigheter kan variera, och endast en vårdpersonal som känner till din medicinska historia kan ge personlig vägledning.
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Artikelhistorik
Informationen på denna sida är skriven och granskad av kvalificerade kliniker.
25 jan 2026 | Ursprungligen publicerad

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