Can I take Losartan and Paracetamol together?

Why this happens

Losartan is a blood pressure medication (angiotensin II receptor blocker) and paracetamol is a painkiller. They are processed by different pathways in the body and do not interfere with how the other works. Unlike some other painkillers (such as ibuprofen), paracetamol does not typically affect blood pressure or kidney function when taken at normal doses.

What you should do

You can take paracetamol while you are on losartan. Always stick to the recommended dose of paracetamol (usually no more than eight 500mg tablets in 24 hours). If you find you need to take paracetamol every day for a long time, it is a good idea to mention this to your doctor or pharmacist so they can monitor your blood pressure.

Important precautions

Pregnancy

You must not take losartan if you are pregnant. It can cause serious harm or death to an unborn baby, especially if taken during the second and third trimesters.

Liver health

Never exceed the recommended dose of paracetamol. Taking too much paracetamol can cause fatal liver damage. Check all other medicines (such as cold and flu remedies) to ensure they do not also contain paracetamol.

Food and drink warnings

Alcohol

It is best to avoid or strictly limit alcohol when taking paracetamol. Combining alcohol and paracetamol increases the risk of serious liver damage.

It is best to avoid or strictly limit alcohol while taking losartan. Alcohol can increase the blood pressure-lowering effect of losartan, which may make you feel dizzy, lightheaded, or faint, especially when standing up. Combining alcohol with medication also increases the risk of liver damage.

Potassium-rich foods (e.g., bananas, spinach, salt substitutes)

Losartan can increase the levels of potassium in your blood. You should avoid using salt substitutes containing potassium (such as Lo-Salt) and speak to your doctor before significantly increasing your intake of potassium-rich foods, as high potassium levels can affect your heart rhythm.

Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.