Aminophylline
Phyllocontin Continus
Granskad av Sid DajaniSenast uppdaterad av Michael Stewart, MRPharmSSenast uppdaterad 28 sept 2022
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Aminophylline helps relieve symptoms such as cough, wheeze and shortness of breath.
You will be prescribed two doses of aminophylline each day - take them 12 hours apart.
Swallow the tablets whole - do not crush or chew them.
If you are a smoker or drink alcohol, ask your doctor for advice, as these can affect the amount of the medicine in your blood.
Överblick
Aminophylline is a bronchodilator medicine used for lung problems like asthma and COPD.
It opens up airways to make breathing easier and relieve symptoms such-as wheezing.
Take tablets whole, twice a day, 12 hours apart, and with or after meals.
Your doctor will adjust your dose based on blood tests.
Tell your doctor if you have heart or liver conditions, or are pregnant or breastfeeding.
If symptoms worsen, contact a doctor or nurse straightaway.
Common side-effects include nausea, headache, fast heartbeat, or feeling shaky.
About aminophylline
Typ av medicin | Xanthine bronchodilator |
Används för | Lung-related problems such as asthma and chronic obstructive pulmonary disease (COPD); sometimes used to treat heart failure |
Även kallad | Phyllocontin Continus® |
Tillgänglig som | Modified-release tablets and injection |
Aminophylline is an oral bronchodilator medicine which is prescribed for people with breathing problems, such as astma och kroniskt obstruktiv lungsjukdom (KOL). It is a medicine that you take by mouth as a tablet. It is also available as an injection, but this is usually given in a hospital environment. Aminophylline is actually a mixture of a medicine called theophylline, and ethylenediamine. The ethylenediamine is used to improve how well the active medicine, theophylline, dissolves.
This medicine works by opening up the air passages in your lungs so that air can flow into your lungs more freely. This makes breathing easier and helps relieve symptoms such as coughing, wheezing and shortness of breath.
Before taking aminophylline
Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking aminophylline it is important that your doctor or pharmacist knows:
Om du är gravid, försöker bli gravid eller ammar.
If you have a heart condition or liver problems.
If you have an overactive thyroid gland gland (hyperthyroidism).
If you have high blood pressure (hypertension).
If you have a stomach ulcer.
If you drink alcohol or smoke.
If you have epilepsy.
If you are currently unwell with a high temperature.
Om du har en sällsynt ärftlig blodsjukdom som kallas porfyri.
If you have been told you have low levels of potassium in your blood.
If you are taking or using any other medicines or inhalers. This includes any medicines you are taking which are available to buy without a prescription, as well as herbal and complementary medicines.
Om du någonsin har haft en allergisk reaktion mot en medicin.
How to take aminophylline
Before starting this treatment, read the manufacturer's printed information leaflet from inside the pack. The leaflet will give you more information about aminophylline and a full list of side-effects which you may experience from taking it.
Aminophylline is taken twice a day, in the morning and evening. Always try to take your doses 12 hours apart and at the same times each day. For example, at 8 am and 8 pm each day. You can take the tablets before or after meals.
Swallow the tablets whole with a drink of water. Do not chew, break, or crush them.
There are two different strengths of tablet available, and you will be asked to take either one or two tablets for each of your doses. Your dose may be adjusted over the first few weeks, depending on the results of some blood tests. The tests allow your doctor to make sure that you have the dose that helps your condition, but avoids any unwanted symptoms.
Your doctor or pharmacist will tell you what strength of tablet is right for you and how many tablets to take for each dose. Your dose will also be on the label of the pack to remind you.
If you forget to take a dose but it is still within four hours of the time you should have taken it, take a dose as soon as you remember. If it is more than four hours since you should have taken it, do not take the missed dose but do remember to take your next dose when it is due. Do not take two doses together to make up for a forgotten dose.
Få ut det mesta av din behandling
Continue to take aminophylline unless your doctor tells you otherwise. Bronchodilators like aminophylline are usually prescribed long-term.
Try to keep your regular appointments with your doctor. This is so your doctor can review your condition on a regular basis. Your doctor will want to test your blood from time to time to make sure that you are receiving the correct dose and also to check the levels of potassium in your blood.
The amount of aminophylline in your blood should be kept within a certain range. It can vary if you are unwell, or if you start or stop smoking, take other medicines, or if you drink more alcohol than usual. This is because these things interfere with the way aminophylline is handled by your body. Some of these things will increase the amount of medicine in your body, leading to side-effects. Others will reduce it, leading to your treatment not being as effective as it should be.
If at any time you find that your symptoms are getting worse, contact a doctor or nurse for advice straightaway.
If you want to buy any medicines, check with a pharmacist that they are safe for you to take. Some medicines (including the herbal remedy St John's wort) can affect the levels of aminophylline in your blood and should not be taken alongside it without your doctor knowing.
Some vaccines, such as the flu vaccine, may also affect aminophylline levels. Make sure you tell your doctor about any vaccinations you have.
If you are due to have an operation or any dental treatment, tell the person carrying out the treatment which medicines you are taking, as some anaesthetics can interfere with aminophylline.
Aminophylline can be very toxic in overdose. If you suspect that someone has taken more than they should (and especially if it is a child), go to the accident and emergency department of your local hospital straightaway. Take the container with you, even if it is empty.
Can aminophylline cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with aminophylline. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following side-effects continue or become troublesome.
Common aminophylline side-effects | Vad kan jag göra om jag upplever detta? |
Feeling sick (nausea), upset stomach | Stick to simple foods - avoid rich or spicy meals. Try taking your doses after meals |
Huvudvärk | Drink plenty of water and ask a pharmacist to recommend a suitable painkiller. If the headaches continue, let your doctor know |
A fast heartbeat, difficulty sleeping, feeling shaky or restless, being sick (vomiting) | If these symptoms continue or are severe, speak with your doctor or pharmacist, they could be a sign your dose is too high |
Itchy rash | This may be a sign of an allergic reaction - let your doctor know about this |
Om du upplever några andra symtom som du tror kan bero på denna medicin, tala med din läkare eller apotekare.
How to store aminophylline
Förvara alla läkemedel utom räckhåll och synhåll för barn.
Förvara på en sval, torr plats, borta från direkt värme och ljus.
Viktig information om alla läkemedel
Viktig information om alla läkemedel
Never take more than the prescribed dose. If you suspect that you or someone else might have taken an overdose of this medicine, go to the accident and emergency department of your local hospital at once. Take the container with you, even if it is empty, so the doctor knows what has been taken.
Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.
Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.
Om du har några frågor om denna medicin, fråga din apotekare.
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Vanliga frågor
What is aminophylline used for?
Aminophylline is prescribed for people with lung-related breathing problems such as asthma and chronic obstructive pulmonary disease (COPD). It is also sometimes used to treat heart failure.
Are there different ways to take aminophylline?
Yes, aminophylline is primarily taken by mouth as modified-release tablets. It is also available as an injection, though this form is typically administered in a hospital setting.
Can aminophylline interact with other substances?
Yes, several factors can affect the levels of aminophylline in your blood. Being unwell, starting or stopping smoking, consuming more alcohol than usual, taking other medicines (including some over-the-counter or herbal remedies like St John's wort), and even certain vaccines (like the flu vaccine) can interfere with how your body processes aminophylline.
What should I do if I think I've taken too much aminophylline?
Aminophylline can be very toxic in overdose. If you suspect that you or someone else has taken more than the prescribed amount, especially a child, you should go to the accident and emergency department of your local hospital immediately. Remember to take the medicine container with you, even if it's empty.
How should I store my aminophylline tablets?
All medicines, including aminophylline, should be kept out of the reach and sight of children. Store the tablets in a cool, dry place, ensuring they are away from direct heat and light.
Vidare läsning och referenser
- Manufacturer's PIL, Phyllocontin Continus® tablets 225 mg, Phyllocontin Forte Continus® tablets 350 mg; Napp Pharmaceuticals Limited, The electronic Medicines Compendium. Dated May 2019.
- Mediciner Komplett BNF 89:e Utgåvan; Brittiska Läkarföreningen och Kungliga Farmaceutiska Sällskapet i Storbritannien, London.
Om författarenVisa fullständig biografi

Helen Allen, MPharm
Apotekare, Medicinsk Författare
MPharm
Helen Allen kvalificerade sig som apotekare 1979 och tillbringade 3 år som författare av läkemedelsinformationsbroschyrer för EMIS.
Om recensenten

Sid Dajani
Sultan Dajani tog examen vid London School of Pharmacy 1994 och blev den yngsta valda medlemmen i Royal Pharmaceutical Society-rådet sedan dess grundande 1842.
Artikelhistorik
Informationen på denna sida är skriven och granskad av kvalificerade kliniker.
Artikeln finns också på Engelska, Tyska, Spanska, Franska, Italienska, Portugisiska, Hindi, Hebreiska, Arabiska, och Svenska.
Nästa granskning: 26 mars 2027
28 sept 2022 | Senaste versionen
7 Jun 2013 | Ursprungligen publicerad
Författad av:
Helen Allen, MPharm

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