Calcitriol ointment for psoriasis
Silkis
Granskad av Sid DajaniSenast uppdaterad av Michael Stewart, MRPharmSLast updated 19 Nov 2024
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Apply a thin layer of ointment twice a day, morning and evening.
Do not use more than the maximum recommended amount of ointment each day.
Remember to wash your hands well after using calcitriol. This will help to prevent accidentally getting it on other areas of your skin, which could cause irritation.
Calcitriol can cause skin irritation. If this becomes severe, stop using the ointment and ask your doctor or pharmacist for further advice.
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About calcitriol
Typ av medicin | A topical vitamin D analogue |
Används för | Plaque psoriasis in adults and in children aged over 12 years |
Även kallad | Silkis® |
Tillgänglig som | Ointment |
Calcitriol is used to treat plaque psoriasis - this is the most common type of psoriasis. It is a condition where red scaly patches called plaques develop on your skin. The most common areas affected are over your elbows and knees, the scalp, and the lower part of your back. The patches may vary in size from time to time and can be itchy. Treatment for psoriasis aims to clear the plaques as much as possible.
Psoriasis is caused by cells in the outer layer of your skin multiplying faster than normal. This causes the older and dead skin cells to build up on the surface of your skin, causing the red scaly patches. Calcitriol works by slowing this overproduction of skin cells which eases the inflamed, scaly areas. It is similar to vitamin D, which is a vitamin essential for healthy skin.
Calcitriol can be taken orally as capsules to treat certain bone problems. Information on this use can be found in our separate medicine leaflet Calcitriol capsules.
Before using calcitriol
Tillbaka till innehållTo make sure that this is the right treatment for you, before you start using calcitriol ointment it is important that your doctor knows:
Om du är gravid, försöker bli gravid eller ammar.
If you have been told you have a form of psoriasis known as erythrodermic or pustular psoriasis. This is because more severe forms of psoriasis like these should only be treated with the close supervision from a skin specialist doctor.
If you have been told you have high calcium levels in your blood, or if your body has problems processing calcium.
If you have any problems with the way your kidneys work, or any problems with the way your liver works.
If you are taking any other medicines or using any other skin preparations. This includes any medicines which are available to buy without a prescription, as well as herbal and complementary medicines.
Om du någonsin har haft en allergisk reaktion mot en medicin.
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How to use calcitriol
Tillbaka till innehållBefore you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about applying calcitriol and will provide you with a full list of the side-effects which you could experience from using it.
Wash and dry the areas of your skin which are affected and then apply a thin layer of ointment. Do this twice each day - it is usually recommended that you apply calcitriol in the morning, and in the evening before going to bed.
You should not use more than 30 g of calcitriol ointment per day, and you should not apply it to more than a third of your body surface area each day. As a guide, a third of your body is approximately one full arm and one full leg. This is because calcitriol is absorbed through your skin and can cause problems if more than these amounts are used.
Wash your hands well afterwards. This will help to prevent the ointment from getting on to any areas of your skin which are unaffected by psoriasis, and causing irritation.
Få ut det mesta av din behandling
Tillbaka till innehållFörsök att hålla dina regelbundna möten med din läkare. Detta är så att din läkare kan följa upp din utveckling.
If you are also using a moisturiser for your skin, use this first and then wait until it has soaked into your skin before you apply calcitriol ointment.
Do not cover any areas of skin that have been treated with calcitriol with a dressing or a bandage. This is because it would cause you to absorb too much calcium into your bloodstream and this will cause problems.
If you have been advised to use calcitriol on your face, apply it carefully so that you do not get any ointment into your eyes. Also, remember to apply a thin layer only, as there is a greater chance it could cause irritation on your face.
You should start to see an improvement in your skin within a few weeks. This improvement will continue for a further few weeks until you feel the full benefit. Continue to apply the ointment regularly for as long as you have been recommended so that you get the full benefit.
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Can calcitriol cause problems?
Tillbaka till innehållAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with calcitriol. You will find a full list in the manufacturer's information leaflet supplied with the medicine. The unwanted effects often improve as your body adjusts to the new medicine but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common calcitriol side-effects (these affect fewer than 1 in 10 people) | Vad kan jag göra om jag upplever detta? |
Skin redness, itching, discomfort or irritation | This is usually mild, but if it continues or becomes severe, please speak with your doctor as it may be a sign of an allergic reaction |
Important: there is a risk of fire when creams and ointments are absorbed by fabrics (such as clothing or bedsheets), making them flammable. A spark or flame can easily ignite the fabric. The risk is highest when large amounts of paraffin-based products are applied and absorb into fabrics. However, there is also a risk when non-paraffin products are used. Be aware of this fire hazard when repeatedly using large amounts of any skin product. Do not smoke or go near naked flames.
When used as directed by your doctor or pharmacist, this product will be applied in small quantities on small areas of skin. There should be minimal absorption into fabrics and a lower risk of fire.
If you experience any other symptoms which you think may be due to the ointment, please speak with your doctor or pharmacist for further advice.
How to store calcitriol
Tillbaka till innehållFörvara alla läkemedel utom räckhåll och synhåll för barn.
Förvara på en sval, torr plats, borta från direkt värme och ljus.
Calcitriol ointment only keeps for eight weeks once the tube has been opened, so do not use any ointment from a tube which has been opened for longer than this. Request a fresh supply through your doctor.
Viktig information om alla läkemedel
Tillbaka till innehållViktig information om alla läkemedel
Om du köper några mediciner, kontrollera med en apotekare att de är säkra att ta tillsammans med dina andra mediciner.
Om du ska genomgå en operation eller tandbehandling, vänligen informera den som utför behandlingen om vilka mediciner du tar eller använder.
Denna beredning är endast avsedd för användning på huden. Om någon av misstag sväljer något av det, gå till akutmottagningen på ditt lokala sjukhus. Ta med behållaren, även om den är tom.
Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.
Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.
Om du har några frågor om denna medicin, fråga din apotekare.
Rapportera biverkningar av ett läkemedel eller vaccin
Om du upplever biverkningar kan du rapportera dem online via Yellow Card website.

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Vidare läsning och referenser
- Manufacturer's PIL, Silkis® 3 micrograms per gram ointment; Galderma (U.K) Ltd, The electronic Medicines Compendium. Dated May 2024.
- Mediciner Komplett BNF 89:e Utgåvan; Brittiska Läkarföreningen och Kungliga Farmaceutiska Sällskapet i Storbritannien, London.
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Artikelhistorik
Informationen på denna sida är skriven och granskad av kvalificerade kliniker.
Next review due: 25 Nov 2027
19 Nov 2024 | Senaste versionen

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