Tazaroten för psoriasis
Zorac
Granskad av Sid DajaniSenast uppdaterad av Michael Stewart, MRPharmSSenast uppdaterad 5 Oct 2024
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Klinisk författares anmärkning Michael Stewart 06/10/2024: Zorac® gel was discontinued in the UK in 2021. At the time of review there are no skin preparations containing tazarotene available in the UK. Tazarotene skin preparations may still be available in other countries. This medicine leaflet is based on medical information available in the UK at the time of writing and is left here for reference purposes. Please also refer to the manufacturer's information supplied with your medicine.
Apply a thin layer of tazarotene gel each evening before going to bed.
Remember to wash your hands well after using the gel. This will help prevent accidentally getting it on other areas of your skin, which could cause irritation.
Överblick
Tazarotene is a gel similar to vitamin A, used for small areas of plaque psoriasis.
It works by slowing down the overproduction of skin cells.
Apply a thin layer to affected areas before bed, remembering to wash your hands afterwards.
Do not use on more than 10% of your body, or on your face, scalp, armpits, or behind elbows and knees.
Your skin may become more sensitive to sunlight, so avoid sun exposure.
Common side-effects include skin irritation, itching, or redness.
Tazarotene can harm an unborn baby; discuss contraception with your doctor.
About tazarotene
Typ av medicin | A topical retinoid (similar to vitamin A) |
Används för | Small areas of plaque psoriasis in adults |
Även kallad | Zorac® (discontinued) |
Tillgänglig som | Gel |
Tazarotene is a gel which is applied to the skin to treat plaque psoriasis. Psoriasis is a condition where red scaly patches develop on your skin, called plaques. Some of the most common areas affected are over your elbows and knees and the lower part of your back. The patches may vary in size from time to time and can be itchy. Treatment for psoriasis aims to clear the plaques as much as possible.
Psoriasis is caused by cells in the outer layer of your skin multiplying faster than normal. This causes the older and dead skin cells to build up on the surface of your skin, causing the red scaly patches. Tazarotene works by slowing the overproduction of your skin cells which eases the inflamed, scaly areas.
Before using tazarotene
To make sure this is the right treatment for you, before you start using tazarotene it is important that your doctor knows:
Om du är gravid, försöker bli gravid eller ammar.
Om du tar eller använder några andra läkemedel. Detta inkluderar alla läkemedel du tar som finns att köpa utan recept, samt växtbaserade och komplementära läkemedel.
Om du någonsin har haft en allergisk reaktion mot en medicin.
How to use tazarotene
Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about applying tazarotene and will provide you with a full list of the side-effects which you could experience from using it.
Tazarotene gel is available in two strengths. Your doctor will probably prescribe the lower-strength gel for you at first to see how your skin reacts, and then may increase the strength if this is necessary. This allows your doctor to make sure that you have the strength that helps your condition but also reduces the risk of skin irritation.
Apply a thin layer of gel before going to bed each night. Apply it only to the areas of your skin which are affected. Remember to wash your hands straightaway afterwards to make sure you don't get the gel into your eyes or on any healthy areas of your skin by accident.
Do not use the gel on more than 10% of your body area (this is roughly equivalent to the total skin area of one arm). Do not use the gel on your face, scalp, armpits or behind your elbows and knees.
Få ut det mesta av din behandling
Försök att hålla dina regelbundna möten med din läkare. Detta är så att din läkare kan följa upp din utveckling.
If your skin becomes very dry or irritated, it may help to use a moisturiser but do this at least an hour before using tazarotene. It is recommended that you do not use any moisturisers or cosmetics for at least an hour after applying tazarotene gel.
Do not cover any areas of skin that have been treated with tazarotene with a dressing or a bandage.
It is likely that your doctor will suggest a course of treatment of up to three months. You should start to see an improvement in your skin within a week or so, and this improvement will continue for several weeks. You should continue to apply the gel regularly for as long as you have been recommended in order to get the full benefit.
Tazarotene could harm an unborn baby so it is important that you do not become pregnant while you are using the gel. Please make sure you have discussed with your doctor which types of contraception are recommended for you, as some hormonal contraceptives (such as the 'mini pill') are not suitable.
Your skin may become more sensitive to sunlight than normal while you are using tazarotene. Try to avoid sitting out in the sun and do not use sunbeds.
Can tazarotene cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with tazarotene. You will find a full list in the manufacturer's information leaflet supplied with the medicine. The unwanted effects often improve as your body adjusts to the new medicine but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Very common tazarotene side-effects (these affect more than 1 in 10 people) | Vad kan jag göra om jag upplever detta? |
Skin itching, irritation, redness, a burning sensation, | Try applying a thinner layer of gel and make sure you avoid getting the gel on any healthy areas of your skin. If this continues, speak with your doctor |
Common tazarotene side-effects (these affect fewer than 1 in 10 people) | Vad kan jag göra om jag upplever detta? |
Peeling, rash or worsening of your condition | Try applying a thinner layer of gel and make sure you avoid getting the gel on any healthy areas of your skin. If this continues, speak with your doctor |
If you experience any other symptoms which you think may be due to the preparation, please speak with your doctor or pharmacist for further advice.
How to store tazarotene
Förvara alla läkemedel utom räckhåll och synhåll för barn.
Förvara på en sval, torr plats, borta från direkt värme och ljus.
Viktig information om alla läkemedel
Viktig information om alla läkemedel
Om du köper några mediciner, kontrollera med en apotekare att de är säkra att ta tillsammans med dina andra mediciner.
Om du ska genomgå en operation eller tandbehandling, vänligen informera den som utför behandlingen om vilka mediciner du tar eller använder.
Denna beredning är endast avsedd för användning på huden. Om någon av misstag sväljer något av det, gå till akutmottagningen på ditt lokala sjukhus. Ta med behållaren, även om den är tom.
Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.
Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.
Om du har några frågor om denna medicin, fråga din apotekare.
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Om du upplever biverkningar kan du rapportera dem online via Yellow Card webbplats.

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Kontrollera möjliga interaktioner mellan läkemedel, kosttillskott och livsmedel innan du tar dem tillsammans.
Vanliga frågor
Can tazarotene cure my plaque psoriasis permanently?
Tazarotene aims to clear the plaques as much as possible by slowing the overproduction of skin cells. While it helps to improve your skin, the article does not state that it offers a permanent cure for psoriasis. You should continue to apply the gel regularly for as long as your doctor recommends to get the full benefit.
Are there any specific types of contraception I should avoid while using tazarotene?
Yes, it is important that you do not become pregnant while using tazarotene as it could harm an unborn baby. Some hormonal contraceptives, such as the 'mini pill', are not suitable. You should discuss with your doctor which types of contraception are recommended for you.
What should I do if my skin becomes very dry or irritated after applying tazarotene?
If your skin becomes very dry or irritated, you can use a moisturiser, but apply it at least an hour before using tazarotene. It's recommended not to use any moisturisers or cosmetics for at least an hour after applying the gel. If irritation or dryness continues, you should speak with your doctor.
How long will I need to use tazarotene gel?
It is likely that your doctor will suggest a course of treatment of up to three months. You should start to see an improvement in your skin within a week or so, and this improvement should continue for several weeks. It's important to continue applying the gel regularly for as long as recommended to get the full benefit.
What should I do if I accidentally get tazarotene gel in my eyes?
The article advises to wash your hands straight away after applying the gel to make sure you don't get it into your eyes by accident. While it doesn't specify what to do if it enters your eyes, general advice for medicated gel is to rinse thoroughly with water, and contact a healthcare professional if irritation persists.
Vidare läsning och referenser
- Manufacturer's PIL, Zorac® gel; Allergan Ltd, The electronic Medicines Compendium. Dated July 2018.
- Mediciner Komplett BNF 89:e Utgåvan; Brittiska Läkarföreningen och Kungliga Farmaceutiska Sällskapet i Storbritannien, London.
Om författarenVisa fullständig biografi

Michael Stewart, MRPharmS
Ansvarig för granskning av medicinbroschyrer – Konsult, Apotekare
BPharm (Hons), MRPharmS
Michael är en apotekare som arbetar i Midlands och South Yorkshire med mer än 20 års erfarenhet av att ge råd om läkemedel och medicinska tillstånd. Han har en stark bakgrund inom vårdutbildning och har producerat och levererat utbildningskurser för apoteksteam och personal inom vårdboenden, inklusive sjuksköterskor. Han har också bidragit till apoteksrådgivande styrelser för hantering av mindre allvarliga tillstånd i samhället.
Om recensenten

Sid Dajani
Sultan Dajani tog examen vid London School of Pharmacy 1994 och blev den yngsta valda medlemmen i Royal Pharmaceutical Society-rådet sedan dess grundande 1842.
Artikelhistorik
Informationen på denna sida är skriven och granskad av kvalificerade kliniker.
Artikeln finns också på Engelska, Tyska, Spanska, Franska, Italienska, Portugisiska, Hindi, Hebreiska, Arabiska, och Svenska.
Next review due: 9 Oct 2027
5 Oct 2024 | Senaste versionen

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