Naproxen tablets for pain and inflammation

About naproxen

Anti-inflammatoriska smärtstillande medel like naproxen are sometimes called non-steroidal anti-inflammatory drugs (NSAIDs), or just 'anti-inflammatories'. Naproxen is used to treat painful conditions such as arthritis, sprains and strains, backache, period (menstrual) cramps, and gout pain.

Naproxen works by blocking the effect of chemicals in your body, called cyclo-oxygenase (COX) enzymes. These enzymes help to make other chemicals in the body, called prostaglandins. Some prostaglandins are produced at sites of injury or damage, and cause pain and inflammation. By blocking the effect of COX enzymes, fewer prostaglandins are produced, which means pain and inflammation are eased.

Naproxen is available on prescription. Short courses of tablets for the treatment of period pain are also available to buy at pharmacies.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking naproxen, it is important that your doctor or pharmacist knows:

• Om du har astma eller någon annan allergisk sjukdom.

• Om du någonsin har haft ett magsår eller duodenalsår, eller om du har en inflammatorisk tarmsjukdom som Crohns sjukdom eller ulcerös kolit.

• Om du är gravid, försöker bli gravid eller ammar.

• If you are over 65 years of age.

• If you have liver problems or kidney disease.

• If you have a heart condition, are at higher risk of heart attack, or have had a problem with your blood vessels or circulation.

• Om du har högt blodtryck.

• Om du någonsin har haft problem med blodkoagulation.

• Om du har högt blodsocker eller kolesterolnivåer.

• If you are a smoker.

• If you have a connective tissue disorder, such as systemic lupus erythematosus (an inflammatory condition also called lupus, or SLE).

• Om du tar några andra läkemedel. Detta inkluderar alla läkemedel du tar som finns att köpa utan recept, samt växtbaserade och komplementära läkemedel.

• If you have ever had an allergic reaction to aspirin or other NSAID (such as indometacin, diclofenac, and ibuprofen), or to any other medicine.
  

• Before you start taking naproxen, read the manufacturer's printed information leaflet from inside the pack. There are several strengths and different formulations of naproxen tablet available. Some formulations have a special coating to help protect your stomach against irritation. They are called 'enteric coated (EC)' or 'gastro-resistant' tablets. The manufacturer's leaflet will give you more information about your tablets, and provide a full list of side-effects which you may experience from taking them.

• Make sure you take the tablets exactly as your doctor or pharmacist tells you to:

  • If you are taking naproxen for a long-term condition (such as ankylosing spondylitis or other forms of arthritis), it is usual for adults to be prescribed 500 mg-1 g daily, to be taken as either a single dose, or divided into two doses during the day. Doses for children depend upon the age of the child.

  • For short-term conditions (such as muscle/tendon pain or sprains/strains), the usual dose is 250 mg taken three of four times daily when needed. It is often recommended that a double dose (500 mg) be taken for the first dose.

  • For gout, the usual dose is 750 mg for the first dose, and then 250 mg every eight hours until the attack has passed.

  • If you have bought naproxen over the counter for period pain, take 250 mg three times daily, for a maximum of three days.

  • The dose of Vimovo® is one tablet twice daily before meals.

• As a general rule, taking naproxen with a glass of milk or after eating some food can help to prevent side-effects such as indigestion. The exception to this rule is if you are taking Vimovo® tablets - these should be taken at least 30 minutes before a meal.

• Many people find it helps to take naproxen tablets with a drink of water.

• Some brands of naproxen are specially coated to protect your stomach from irritation. Do not chew or break the tablets, as this will stop the coating from working properly.

• If you have been given enteric coated (EC) tablets, do not take any indigestion remedies during the two hours before taking naproxen, or during the two hours after taking it. This is because antacids stop the protective coating from working as it should.

• If you forget to take a dose, take it as soon as you remember unless it is nearly time for your next dose, in which case leave out the missed dose. Do not take two doses together to make up for a missed dose.

• Your doctor will try to prescribe you the lowest dose for the shortest time in order to reduce the risk of side-effects. If you need to take naproxen for a long time, your doctor may want to prescribe another medicine along with it to protect your stomach or intestines from irritation. Alternatively, you may be prescribed a brand of naproxen which already contains a protective medicine. An example of a combination brand is Vimovo® which contains naproxen and esomeprazole.

• Try to keep any regular appointments with your doctor. This is so your doctor can check on your progress, and is especially important if you are taking naproxen for a long-term condition.

• If you have asthma, symptoms such as wheeze or breathlessness can be made worse by anti-inflammatories such as naproxen. If this happens to you, you should stop taking the tablets and see your doctor as soon as possible.

• If you buy any medicines, check with a pharmacist that they are safe to take with an anti-inflammatory like naproxen. This is because you should not take these tablets with any other anti-inflammatory painkiller, some of which are available in cold and flu remedies which can be bought over the counter.

• Om du ska genomgå en operation eller tandbehandling, informera den som utför behandlingen om vilka mediciner du tar.

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with naproxen. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Viktigt: if you experience any of the following less common but more serious symptoms, stop taking naproxen and contact your doctor for advice straightaway:

• Om du har några andningssvårigheter som väsande andning eller andfåddhet.

• Om du har några tecken på en allergisk reaktion, såsom svullnad runt munnen eller ansiktet, eller ett allvarligt kliande hudutslag.

• If you pass blood or black stools, vomit blood, or have severe tummy (abdominal) pains.

If you experience any other symptoms which you think may be due to this medicine, call your doctor or pharmacist for further advice.

• Förvara alla läkemedel utom räckhåll och synhåll för barn.

• Förvara på en sval, torr plats, borta från direkt värme och ljus.