Trazodone
Molipaxin
Granskad av Dr Colin Tidy, MRCGPSenast uppdaterad av Michael Stewart, MRPharmSLast updated 7 Nov 2022
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Keep your regular appointments with your doctor. This is so your doctor can check on your progress.
Take your doses after a meal or a snack. Try not to drink any alcohol whilst being treated with trazodone as it will increase the chance of you feeling drowsy.
Common side effects of trazodone include drowsiness, dizziness, dry mouth, headache, and nausea.
This medicine may make you sleepy. If this happens, do not drive and do not use tools or machines.
Tell your doctor if you experience any troublesome side effects.
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About trazodone
Typ av medicin | Tricyclic-related antidepressant |
Används för | Depression and/or anxiety in adults |
Även kallad | Molipaxin® |
Tillgänglig som | Capsules, tablets, and liquid medicine |
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What is trazodone used for?
Trazodone is used to treat depression och ångest. It is a type of medicine called a tricyclic-related antidepressant.
Antidepressants like trazodone are used to ease symptoms such as low mood, poor sleep and poor concentration. This in turn allows you to function more normally and cope better with any difficult circumstances. Trazodone also helps to reduce the symptoms of anxiety, even if you are not depressed.
Depression and anxiety can develop for no apparent reason, or they may be triggered by a life event such as a relationship problem, bereavement, or illness.
Side effects of trazodone
Tillbaka till innehållThe most common side effects of trazodone are:
Feeling dizzy or faint.
Feeling sleepy or tired.
Blurred vision.
Torr mun.
Förstoppning.
Headache.
You may also experience other side effects such as:
Feeling irritable or confused.
Tingling sensation or a numb feeling.
Breast tenderness.
Not being able to ejaculate.
Increased or decreased sex drive (libido).
Increased appetite and weight gain.
Difficulty peeing.
Indigestion.
Fast heartbeat.
General aches and pains.
You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
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How to manage trazodone side effects
Tillbaka till innehållCommon trazodone side effects | Vad kan jag göra om jag upplever detta? |
Feeling dizzy or faint | Getting up more slowly may help. If you begin to feel faint, sit down until the feeling passes |
Feeling sleepy or tired, blurred vision | Om detta händer, kör inte och använd inte verktyg eller maskiner. Drick inte alkohol |
Torr mun | Försök tugga sockerfritt tuggummi eller suga på sockerfria karameller |
Förstoppning | Try to eat a well-balanced diet containing plenty of fibre, and drink plenty of water |
Feeling irritable or confused, tingling or numb feelings, breast tenderness, difficulties with sexual function, increased appetite and weight gain, difficulty passing urine, indigestion, a fast heartbeat, aches and pains | Speak with your doctor if any of these become troublesome |
Om du upplever några andra symtom som du tror kan bero på denna medicin, tala med din läkare eller apotekare.
Who should not take trazodone?
Tillbaka till innehållSome medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking trazodone it is important that your doctor or pharmacist knows:
Om du är gravid, försöker bli gravid eller ammar.
If you have thyroid problems.
If you have liver, kidney or heart problems.
If you have epilepsy or diabetes (diabetes mellitus).
If you are troubled by constipation which lasts several days.
If you have any difficulties passing urine, or have had prostate trouble.
If you have ever had a mental health problem (such as bipolar disorder or psychosis).
If you have increased pressure in the eye (glaucoma).
If you have been told you have a tumour on your adrenal gland, called phaeochromocytoma.
If you have a rare inherited blood disorder called porphyria.
If you are taking other medicines, including those available to buy without a prescription, as well as herbal and complementary medicines. This is especially important if you have recently taken a medicine for depression, known as a monoamine-oxidase inhibitor (MAOI).
Om du någonsin har haft en allergisk reaktion mot en medicin.
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How to take trazodone
Tillbaka till innehållRead the manufacturer's printed information leaflet from inside your pack. This will give you more information about trazodone and a full list of side effects which you may experience from taking it.
You may be prescribed trazodone to take once a day, at bedtime. Some doctors, however, may recommend smaller doses taken two or three times a day. Your doctor will tell you which is right for you and your dose will also be on the label of the pack to remind you.
Take trazodone exactly as your doctor has told you to. It can cause drowsiness so your doctor may advise you to take a smaller dose to begin with, and then to increase it as your body gets used to the medicine.
Take trazodone after meals. If you are taking your doses at bedtime, have a light snack beforehand.
If you forget to take a dose take it as soon as you remember, unless it is nearly time for your next dose in which case leave out the forgotten dose. Do not take two doses together to make up for a missed dose.
Få ut det mesta av din behandling
Tillbaka till innehållFörsök att hålla dina regelbundna möten med din läkare. Detta är så att din läkare kan följa upp din utveckling.
You may feel that trazodone is not working for you straightaway. It can take a week or two after starting it before the effect begins to build up, and 4-6 weeks before you feel the full benefit. It is important that you do not stop taking it after a week or so, thinking it is not helping.
If you feel depressed, you may have distressing thoughts and think about harming yourself or ending your life. If this happens, it is very important that you tell your doctor about this as soon as possible.
If you drink alcohol, ask your doctor for advice. Your doctor is likely to recommend that you do not drink alcohol while you are on trazodone, as it increases the risk of side effects, such as feeling sleepy.
If you are taking trazodone for depression, your doctor may ask you to carry on taking it even after you feel better. This is to help stop the depression from returning.
It is normal for a course of treatment to last for around six months after your symptoms have eased.
Continue to take trazodone unless your doctor tells you otherwise. Stopping treatment suddenly can sometimes cause problems and your doctor may want you to reduce your dose gradually if this is necessary.
If you buy any medicines, check with a pharmacist that they are suitable for you to take. This is because a number of medicines which can be bought from pharmacies and other retail outlets can increase the risk of side effects from trazodone. These include antihistamine medicines, and St John's wort.
If you have diabetes you may need to check your blood sugar (glucose) more frequently. This is because trazodone may affect the levels of sugar in your blood. Your doctor will advise you about this.
If you are having any medical or dental treatment, tell the person carrying out the treatment that you are taking this medicine.
How to store trazodone
Tillbaka till innehållFörvara alla läkemedel utom räckhåll och synhåll för barn.
Förvara på en sval, torr plats, borta från direkt värme och ljus.
Viktig information om alla läkemedel
Tillbaka till innehållViktig information om alla läkemedel
Ta aldrig mer än den föreskrivna dosen. Om du misstänker att du eller någon annan kan ha tagit en överdos av denna medicin, gå omedelbart till akutmottagningen på ditt lokala sjukhus. Ta med behållaren, även om den är tom.
Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.
Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.
Om du har några frågor om denna medicin, fråga din apotekare.
Rapportera biverkningar av ett läkemedel eller vaccin
Om du upplever biverkningar kan du rapportera dem online via Yellow Card website.
Vanliga frågor
Tillbaka till innehållIs trazodone a SSRI or SNRI?
Trazodone is neither an SSRI nor an SNRI, it is a SARI (serotonin antagonist and reuptake inhibitor).
How long after I take trazodone will I fall asleep?
Trazodone usually helps with sleep within 30-60 minutes, however it may take a few nights for it to consistently work.
Is trazodone a controlled drug?
Trazodone is not a controlled drug, but it is prescription-only and should be taken under medical supervision.
Will trazodone affect my sex drive?
Trazodone can cause some people to have a lower sex drive, difficulty with arousal, or delayed orgasm, while others experience little or no change.
Does trazodone make you gain weight?
Trazodone may cause weight gain due to an increased appetite, but most people don’t gain a significant amount. Speak to your doctor if any weight gain is concerning or bothering you.

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Vidare läsning och referenser
- Manufacturer's PIL, Trazodone Hydrochloride 50 mg and 100 mg Capsules; Zentiva, The electronic Medicines Compendium. Dated February 2022.
- Mediciner Komplett BNF 89:e Utgåvan; Brittiska Läkarföreningen och Kungliga Farmaceutiska Sällskapet i Storbritannien, London.
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Artikelhistorik
Informationen på denna sida är skriven och granskad av kvalificerade kliniker.
Next review due: 6 May 2027
7 Nov 2022 | Senaste versionen

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