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Can I take Allopurinol and Candesartan together?

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Taking allopurinol and candesartan together may increase the risk of a rare but serious allergic reaction. It can also lead to a higher risk of your blood pressure dropping too low or your kidney function being affected.

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Varför detta händer

Both drugs can affect how the kidneys work. When used together, they may increase the sensitivity of the immune system, making a severe skin rash or allergic reaction more likely. Additionally, they can have an additive effect on lowering blood pressure and kidney filtration.

You can usually take these together, but you must be monitored by your doctor. Seek immediate medical help if you develop a skin rash, hives, or swelling of the face. Your doctor may want to perform regular blood tests to check your kidney function and monitor your blood pressure closely.

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Severe skin reactions (SCARs)

Stop taking allopurinol immediately and seek urgent medical help if you develop a skin rash, peeling skin, or mouth ulcers. This can be a sign of a rare but life-threatening allergic reaction.

Graviditet

Do not take candesartan if you are pregnant or planning to become pregnant. It can cause serious harm or death to an unborn baby, particularly if used in the second and third trimesters.

High potassium levels (Hyperkalaemia)

Avoid using potassium supplements or salt substitutes containing potassium while taking candesartan, as it can cause dangerously high levels of potassium in your blood.

Alkohol

Alcohol can increase the levels of uric acid in your blood, which makes allopurinol less effective at preventing gout attacks. It is best to limit your intake, especially beer and spirits.

It is best to avoid or strictly limit alcohol while taking candesartan. Combining alcohol with this medicine can cause your blood pressure to drop too low, making you feel dizzy, lightheaded, or faint, especially when standing up. Alcohol also increases the risk of dehydration, which can affect your kidney function while on this medication.

Caffeine

High intake of caffeine may interfere with how allopurinol works to lower uric acid. Try to keep your intake of tea, coffee, and cola consistent.

Water/Hydration

You must drink plenty of fluids (at least 2 to 3 litres a day) while taking allopurinol. This helps to prevent the formation of kidney stones and ensures your kidneys can flush out uric acid effectively.

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Taking multiple medicines? Our Interaktionskontroll för läkemedel helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Ansvarsfriskrivning

Denna information är endast avsedd för allmän utbildning och bör inte användas som en ersättning för professionell medicinsk rådgivning. Rådfråga alltid din läkare, apotekare eller annan kvalificerad vårdpersonal innan du fattar beslut om dina mediciner. Individuella omständigheter kan variera, och endast en vårdpersonal som känner till din medicinska historia kan ge personlig vägledning.

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Artikelhistorik

Informationen på denna sida är skriven och granskad av kvalificerade kliniker.

  • 25 jan 2026 | Ursprungligen publicerad
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