Hoppa till huvudinnehåll

Can I take Sertraline and Alcohol together?

Guide för läkemedelsinteraktioner

Drinking alcohol while taking sertraline can make you feel much more drowsy, dizzy, or sleepy than usual. It can also impair your coordination, reaction times, and judgement. In some cases, alcohol can make the symptoms of your depression or anxiety worse, or increase the risk of suicidal thoughts. Additionally, both substances can affect your liver, and combining them may increase the risk of rare but serious side effects like 'serotonin syndrome', which causes confusion, sweating, and a rapid heartbeat.

Video picks for Läkemedelsinteraktioner

Fortsätt läsa nedan

Varför detta händer

Sertraline and alcohol both affect the central nervous system (the brain). When taken together, they have an 'additive effect', meaning they enhance each other's sedative properties. Alcohol can also interfere with how the brain processes serotonin, the chemical that sertraline is designed to balance.

It is best to avoid drinking alcohol altogether while taking sertraline, especially when you first start the medication or if your dose has recently increased. If you do choose to drink, keep it to a very small amount, drink slowly with food, and be aware that one drink may affect you much more strongly than usual. Do not drive or operate machinery if you have been drinking.

Fortsätt läsa nedan

Depression and anxiety disorders

You may experience an increase in suicidal thoughts or the urge to self-harm when first starting sertraline or changing the dose. This is more common in young adults under 25. Contact your doctor or go to hospital immediately if you notice any changes in your mood or behaviour.

Serotonin Syndrome

Sertraline can cause a life-threatening condition called serotonin syndrome, especially if taken with other medicines that affect serotonin (such as triptans, tramadol, or St John's Wort). Seek urgent medical help if you experience agitation, hallucinations, fast heartbeat, or severe muscle stiffness.

Bleeding disorders

Sertraline can increase your risk of bleeding, particularly from the stomach. Use with caution if you take blood-thinning medicines (like warfarin) or anti-inflammatory painkillers (like ibuprofen or aspirin), as this significantly increases the risk of serious bleeding.

Alkohol

It is best to avoid or strictly limit alcohol while taking sertraline. Combining alcohol with this medicine can increase side effects such as drowsiness, dizziness, and impaired coordination. It may also make your depression or anxiety symptoms worse.

Grapefruit juice

You should avoid drinking large amounts of grapefruit juice while taking sertraline. Grapefruit can increase the level of sertraline in your blood, which may increase the risk of side effects.

Fortsätt läsa nedan

Taking multiple medicines? Our Interaktionskontroll för läkemedel helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Ansvarsfriskrivning

Denna information är endast avsedd för allmän utbildning och bör inte användas som en ersättning för professionell medicinsk rådgivning. Rådfråga alltid din läkare, apotekare eller annan kvalificerad vårdpersonal innan du fattar beslut om dina mediciner. Individuella omständigheter kan variera, och endast en vårdpersonal som känner till din medicinska historia kan ge personlig vägledning.

Fortsätt läsa nedan

Artikelhistorik

Informationen på denna sida är skriven och granskad av kvalificerade kliniker.

  • 25 jan 2026 | Ursprungligen publicerad
flu eligibility checker

Fråga, dela, anslut.

Bläddra i diskussioner, ställ frågor och dela erfarenheter inom hundratals hälsorelaterade ämnen.

symptom checker

Känner du dig sjuk?

Bedöm dina symtom online gratis

Anmäl dig till Patientens nyhetsbrev

Din veckovisa dos av tydliga, pålitliga hälsoråd - skrivna för att hjälpa dig känna dig informerad, självsäker och i kontroll.

Vänligen ange en giltig e-postadress

By subscribing you accept our Sekretesspolicy. Du kan avsluta prenumerationen när som helst. Vi säljer aldrig dina uppgifter.