Can I take Atorvastatin and Paracetamol together?

Varför detta händer

Atorvastatin and paracetamol are processed by different pathways in the liver. Atorvastatin is primarily broken down by an enzyme called CYP3A4, while paracetamol is processed through different chemical pathways (glucuronidation and sulfation). Because they do not compete for the same 'machinery' in the body, they do not interfere with each other's levels.

You can continue to take both medicines as prescribed. Always stick to the recommended dose of paracetamol (usually no more than eight 500mg tablets in 24 hours) and inform your doctor if you experience any unusual muscle pain, which is a known side effect of statins regardless of paracetamol use.

Graviditet

You must not take atorvastatin if you are pregnant or planning to become pregnant, as it can cause serious harm to an unborn baby. Use effective contraception while taking this medicine.

Muscle disorders - atorvastatin

Seek immediate medical advice if you experience unexplained muscle pain, tenderness, or weakness. In rare cases, this can lead to a serious condition called rhabdomyolysis which causes kidney damage.

Liver health and multi-ingredient medicines

Do not take more than one medicine containing paracetamol at a time (such as some cold and flu remedies). Exceeding the maximum daily dose can cause fatal liver damage.

Grapefruit juice

Grapefruit juice contains compounds that can increase the level of atorvastatin in your blood. This may increase your risk of side effects, such as muscle pain or damage. Avoid drinking large quantities (more than 1.2 litres per day), though it is safest to avoid it altogether or keep intake to very small amounts.

Alkohol

For atorvastatin: Drinking large amounts of alcohol regularly can increase your risk of liver problems. For paracetamol: Regular heavy drinking increases the risk of liver damage if you take paracetamol, especially if you exceed the recommended dose. It is best to keep alcohol intake within the recommended low-risk limits.

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Ansvarsfriskrivning

Denna information är endast avsedd för allmän utbildning och bör inte användas som en ersättning för professionell medicinsk rådgivning. Rådfråga alltid din läkare, apotekare eller annan kvalificerad vårdpersonal innan du fattar beslut om dina mediciner. Individuella omständigheter kan variera, och endast en vårdpersonal som känner till din medicinska historia kan ge personlig vägledning.