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Can I take Clarithromycin and Ibuprofen together?

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There is no direct interaction between clarithromycin and ibuprofen that would prevent them from being taken together. However, both medications can occasionally cause stomach upset or irritation. Taking them at the same time might increase the chance of experiencing nausea, indigestion, or stomach pain. Additionally, if you are taking clarithromycin for a severe infection, your doctor may advise you to avoid ibuprofen if there are concerns about your kidney function or hydration levels.

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Varför detta händer

Clarithromycin is an antibiotic and ibuprofen is a non-steroidal anti-inflammatory drug (NSAID). They do not significantly interfere with how the body processes (metabolises) each other. The main concern is a 'pharmacodynamic' one, where both drugs have the potential to irritate the lining of the stomach or put slight stress on the kidneys, though this is rarely a problem for healthy individuals.

It is generally safe to take these two medicines together. To protect your stomach, try to take both the clarithromycin and the ibuprofen with food or a milky drink. If you develop severe stomach pain, persistent vomiting, or if you feel very dehydrated, stop taking the ibuprofen and speak to your doctor or pharmacist. Always complete the full course of your antibiotic.

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Heart rhythm disorders (Long QT syndrome)

Clarithromycin can cause serious heart rhythm problems. You must not take it if you have a history of 'Long QT syndrome' or are taking other medicines that affect your heart rate.

Astma

Do not take ibuprofen if you have asthma, as it can cause a life-threatening worsening of your breathing or a severe allergic reaction.

Stomach ulcers or kidney problems

Avoid ibuprofen if you have ever had a stomach ulcer, perforation, or bleeding, or if you have severe kidney disease, as it can cause serious internal bleeding or kidney failure.

Alkohol

While there is no direct interaction, both clarithromycin and alcohol can cause side effects like nausea, dizziness, or stomach upset. It is generally best to avoid alcohol until you have finished your course and feel better.

Food (General)

You should ideally take ibuprofen with food or a glass of milk to reduce the risk of indigestion or stomach irritation.

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Taking multiple medicines? Our Interaktionskontroll för läkemedel helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Ansvarsfriskrivning

Denna information är endast avsedd för allmän utbildning och bör inte användas som en ersättning för professionell medicinsk rådgivning. Rådfråga alltid din läkare, apotekare eller annan kvalificerad vårdpersonal innan du fattar beslut om dina mediciner. Individuella omständigheter kan variera, och endast en vårdpersonal som känner till din medicinska historia kan ge personlig vägledning.

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Artikelhistorik

Informationen på denna sida är skriven och granskad av kvalificerade kliniker.

  • 25 jan 2026 | Ursprungligen publicerad
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