Can I take Danazol and Tramadol together?

Varför detta händer

Tramadol is broken down in the liver by specific enzymes. Danazol blocks these enzymes, preventing the body from clearing the tramadol. This leads to a build-up of the painkiller to potentially toxic levels.

You should speak to your doctor before taking these two medicines together. Your doctor may need to adjust your dose of tramadol or monitor you more closely for side effects. If you feel unusually dizzy, sleepy, or have trouble breathing, seek medical help immediately.

Graviditet

You must not take danazol if you are pregnant or planning to become pregnant. It can cause the development of male physical characteristics in a female fetus. You must use effective, non-hormonal contraception (such as condoms) while taking it.

Blood clots (Thromboembolism)

Danazol significantly increases the risk of serious blood clots. Seek immediate medical help if you experience sudden leg swelling, chest pain, or shortness of breath.

Liver disease

Danazol can cause serious liver damage and non-cancerous liver tumours. You will need regular blood tests to monitor your liver function while taking this medicine.

Epilepsy or history of seizures

Tramadol can increase the risk of having a fit (seizure), even at the recommended dose. This risk is higher if you already have epilepsy or are taking certain antidepressants.

Asthma or breathing problems

Tramadol can cause dangerous breathing difficulties (respiratory depression). You must not take it if you have severe asthma or significant breathing problems.

Alkohol

It is best to avoid or strictly limit alcohol while taking danazol. Combining danazol with alcohol can cause you to feel nauseous or short of breath (a disulfiram-like reaction). Additionally, both danazol and alcohol can put strain on your liver, and using them together increases the risk of liver damage.

It is best to avoid or strictly limit alcohol while taking tramadol. Combining alcohol with tramadol significantly increases the risk of dangerous side effects, such as extreme sleepiness, breathing difficulties, and loss of consciousness.

Taking multiple medicines? Our Interaktionskontroll för läkemedel helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Ansvarsfriskrivning

Denna information är endast avsedd för allmän utbildning och bör inte användas som en ersättning för professionell medicinsk rådgivning. Rådfråga alltid din läkare, apotekare eller annan kvalificerad vårdpersonal innan du fattar beslut om dina mediciner. Individuella omständigheter kan variera, och endast en vårdpersonal som känner till din medicinska historia kan ge personlig vägledning.