Can I take Pancreatin and Morphine together?

Varför detta händer

Morphine is an opioid that reduces gastrointestinal motility (how fast food moves through your gut). Pancreatin relies on being in the right part of the small intestine at the same time as food to help with digestion. By slowing down the stomach and intestines, morphine can cause a mismatch between when the enzymes are released and when the food is ready to be digested.

It is generally fine to take these together, but you should be aware that morphine-induced constipation or slow digestion might affect how well your pancreatin works. If you notice increased symptoms like fatty stools, stomach pain, or bloating while taking morphine, speak to your doctor. Ensure you manage any constipation caused by morphine effectively.

Respiratory conditions (e.g. COPD, severe asthma)

Morphine can dangerously slow your breathing. You must not take it if you have severe breathing difficulties or are having an acute asthma attack.

Pork allergy

Pancreatin is made from the pancreas of pigs. You must not take it if you have a confirmed allergy to pork or porcine products.

Fibrosing colonopathy

If you experience unusual abdominal pain, swelling, or constipation, contact your doctor immediately. High doses of pancreatin have rarely been linked to a serious bowel condition called fibrosing colonopathy.

Mouth irritation

Do not hold the capsules or powder in your mouth. Pancreatin contains active enzymes that can cause severe irritation and ulcers of the mouth and throat if not swallowed immediately with plenty of water.

Alkohol

It is best to avoid or strictly limit alcohol when taking pancreatin. Alcohol can worsen the underlying conditions for which pancreatin is prescribed (such as pancreatitis) and can interfere with how well your body absorbs nutrients.

It is best to avoid or strictly limit alcohol while taking morphine. Combining alcohol with morphine significantly increases the risk of dangerous side effects, such as extreme sleepiness, breathing difficulties, and a potentially fatal overdose. Alcohol can also cause some slow-release morphine tablets to release the medicine too quickly into your system (known as 'dose dumping').

Hot food and drinks

Do not mix pancreatin capsules or powder with very hot food or drinks. Heat can destroy the enzymes in the medicine, making it less effective at helping you digest your food.

Alkaline foods (e.g., milk, yoghurt) - pancreatin

If you open the capsules to sprinkle the granules onto food, do not use alkaline foods like milk or yoghurt. The granules have a protective coating that dissolves in alkaline environments; if this happens in your mouth or throat, it can cause irritation and the medicine will not work properly in your gut. Use acidic food like apple sauce instead.

Taking multiple medicines? Our Interaktionskontroll för läkemedel helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Ansvarsfriskrivning

Denna information är endast avsedd för allmän utbildning och bör inte användas som en ersättning för professionell medicinsk rådgivning. Rådfråga alltid din läkare, apotekare eller annan kvalificerad vårdpersonal innan du fattar beslut om dina mediciner. Individuella omständigheter kan variera, och endast en vårdpersonal som känner till din medicinska historia kan ge personlig vägledning.