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Can I take Paracetamol and Ibuprofen together?

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There is no harmful interaction between paracetamol and ibuprofen. In fact, they are often taken together because they work in different ways to provide better pain relief than either medicine alone.

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It is safe to take paracetamol och ibuprofen together as long as you follow the recommended doses and don’t have medical conditions that make ibuprofen unsafe (such as stomach ulcers, kidney problems, or certain heart conditions).

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How they work

Paracetamol and ibuprofen belong to different classes of painkillers. Paracetamol works mainly in the central nervous system to reduce pain and fever, while ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) that reduces inflammation and pain at the site of injury.

Because they are processed by the body differently (paracetamol by the liver and ibuprofen primarily by the kidneys), they do not interfere with each other's absorption or metabolism.

It is safe to take paracetamol and ibuprofen at the same time, or you can stagger them (taking one, then the other a few hours later).

  • Always follow the dosage instructions on the packaging for each medicine.

  • Do not exceed the maximum daily dose for either.

  • If you have underlying kidney, liver, or stomach issues, consult your pharmacist or doctor before use.

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Astma

Do not take ibuprofen if you have asthma, as it can cause a life-threatening worsening of your breathing or a severe allergic reaction.

Stomach ulcers or bleeding

Avoid ibuprofen if you have ever had a stomach ulcer, perforation, or bleeding, as it can cause serious damage to the stomach lining.

Liver disease or high alcohol intake

Taking more than the recommended dose of paracetamol can cause fatal liver damage. Do not take with any other products containing paracetamol (such as cold and flu remedies).

Pregnancy (third trimester)

Do not take ibuprofen if you are more than 28 weeks pregnant, as it can cause serious heart and kidney problems in the unborn baby and complications during birth.

Alkohol

While a small amount of alcohol is generally considered safe, chronic heavy drinking or binge drinking increases the risk of liver damage when taking paracetamol. For ibuprofen, alcohol can increase the risk of stomach irritation and bleeding. It is best to limit alcohol intake while taking these medicines.

Food (General)

Ibuprofen should ideally be taken with food or a glass of milk. This helps to reduce the risk of stomach upset, indigestion, or irritation to the stomach lining.

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Taking multiple medicines? Our Interaktionskontroll för läkemedel helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Ansvarsfriskrivning

Denna information är endast avsedd för allmän utbildning och bör inte användas som en ersättning för professionell medicinsk rådgivning. Rådfråga alltid din läkare, apotekare eller annan kvalificerad vårdpersonal innan du fattar beslut om dina mediciner. Individuella omständigheter kan variera, och endast en vårdpersonal som känner till din medicinska historia kan ge personlig vägledning.

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Artikelhistorik

Informationen på denna sida är skriven och granskad av kvalificerade kliniker.

  • 25 jan 2026 | Ursprungligen publicerad
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