Apixaban-tabletter
Eliquis
Granskad av Sid DajaniSenast uppdaterad av Michael Stewart, MRPharmSSenast uppdaterad 27 Oct 2022
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You will have been prescribed apixaban either to treat a harmful clot that has formed in a blood vessel, or to prevent one from forming.
The usual dose is one tablet taken twice a day, morning and evening.
The most common side-effects are bleeding (such as nosebleeds) and anaemia.
Överblick
Apixaban (Eliquis) is a medicine used to prevent or treat harmful blood clots.
It works by blocking a substance in your blood called factor Xa, which is involved in clotting.
Apixaban is usually taken twice a day, with or without food.
Unlike warfarin, apixaban does not require regular blood tests.
Tell your doctor about any medical conditions or other medicines you are taking before starting apixaban.
Seek medical advice immediately if you experience unusual or persistent bleeding.
About apixaban
Typ av medicin | A factor Xa inhibitor anticoagulant |
Används för | To prevent or treat harmful blood clots |
Also called (UK and USA) | Eliquis® |
Tillgänglig som | Tabletter |
Apixaban works by preventing your blood from clotting as quickly or as effectively as normal. It does this by blocking a substance in your blood, called 'factor Xa', which is involved in the development of blood clots.
Sometimes, harmful blood clots can form in the blood vessels of your legs, lungs, brain or heart, and cause a blockage. This is more likely to happen if you have had surgery, or if you have a fast irregular heartbeat. For many years, a medicine called warfarin has been commonly used to help protect against this. However, people who take warfarin need to have regular blood tests to measure how quickly their blood clots. This often means that the dose of warfarin can change quite frequently. Apixaban works in a slightly different way to warfarin, so people who take apixaban do not need to have regular blood tests.
Apixaban is prescribed to treat blood clots causing deep vein thrombosis and pulmonary embolism. You may also be prescribed apixaban to help protect against recurrent blood clots, or if you have a certain type of irregular fast heartbeat known as förmaksflimmer.
Before taking apixaban
Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking apixaban it is important that your doctor knows:
Om du är gravid eller ammar.
If you have any medical problems that increase your risk of bleeding, or if you have recently had surgery.
If you have any problems with the way your liver works, or with the way your kidneys work.
If you have been told you have a condition called antiphospholipid syndrome.
Om du någonsin har haft en allergisk reaktion mot en medicin.
Om du tar några andra läkemedel. Detta inkluderar alla läkemedel du tar som finns att köpa utan recept, samt växtbaserade och komplementära läkemedel.
How to take apixaban tablets
Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about apixaban and will provide you with a full list of the side-effects which you could experience from taking it.
Take apixaban exactly as your doctor tells you to. It is taken twice a day, preferably in the morning and the evening. Your doctor or pharmacist will tell you which strength of tablet is right for you as there are two strengths of apixaban available - 2.5 mg and 5 mg. This information will also be printed on the label of the pack to remind you.
Apixaban can be taken either with or without food. Swallow the tablet with a drink of water. If you have difficulty swallowing the tablet whole, you can crush the tablet and then mix it with 30 ml (two tablespoons) of water or apple juice, or alternatively, add it to some apple purée. Swallow the mixture as soon as it has been made up.
If you forget to take a dose at the usual time, take it as soon as you remember. Try to take the correct number of doses each day, but do not take two doses together to make up for a forgotten dose.
Få ut det mesta av din behandling
Försök att hålla alla regelbundna möten med din läkare. Detta är så att din läkare kan följa upp din utveckling.
The length of the course of treatment will depend upon why you are taking the tablets, but it will either be for a few weeks, or long-term. If you have had hip or knee surgery, you will be asked to continue taking apixaban for a certain number of weeks. If you are taking it to protect you from blood clots developing (such as if you have atrial fibrillation), you will be asked to continue to take it over a longer period of time.
If you take any medicines that you have bought without a prescription, check with a pharmacist that they are suitable to take with apixaban. This is because some medicines, such as aspirin and some anti-inflammatory painkillers, can interfere with it.
If you are due to have an operation or dental treatment, tell the person carrying out the treatment which medicines you are taking. This is because it may become necessary for you to stop taking apixaban for a day or so.
Can apixaban tablets cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with apixaban. The best place to find a full list of the side-effects which can be associated with your medicine, is from the manufacturer's printed information leaflet supplied with the medicine. Alternatively, you can find an example of a manufacturer's information leaflet in the reference section below. Speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common apixaban side-effects (these affect fewer than 1 in 10 people) | Vad kan jag göra om jag upplever detta? |
Bleeding (such as nosebleeds, bleeding gums) or bruising | If this continues or becomes troublesome, let your doctor know |
Anaemia (which could make you feel very tired) | Your doctor will check for this |
Känner dig illamående (nausea) | Try taking your doses with something to eat |
Viktigt: if you experience any unusual bleeding, or bleeding that doesn't stop within ten minutes, speak with your doctor straightaway or go to your local accident and emergency department.
Om du upplever några andra symtom som du tror kan bero på tabletterna, tala med din läkare eller apotekare för vidare råd.
How to store apixaban
Förvara alla läkemedel utom räckhåll och synhåll för barn.
Förvara på en sval, torr plats, borta från direkt värme och ljus.
Viktig information om alla läkemedel
Viktig information om alla läkemedel
Ta aldrig mer än den föreskrivna dosen. Om du misstänker att du eller någon annan kan ha tagit en överdos av denna medicin, gå till akutmottagningen på ditt lokala sjukhus. Ta med behållaren, även om den är tom.
Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.
Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.
Om du har några frågor om denna medicin, fråga din apotekare.
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Vanliga frågor
What is the difference between Apixaban and Warfarin?
Apixaban and warfarin both help prevent blood clots. However, people taking warfarin need regular blood tests to monitor clotting times and adjust the dose, as it can change frequently. Apixaban works differently, so these regular blood tests are not necessary.
How long will I need to take Apixaban for?
The duration of your Apixaban treatment depends on why you are taking it. It could be for a few weeks, for example after hip or knee surgery, or it might be for a longer period, such as if you have atrial fibrillation to protect against blood clots.
Does Apixaban cause tiredness?
Yes, anaemia is a common side-effect of Apixaban, affecting fewer than 1 in 10 people, and it can make you feel very tired. Your doctor will monitor you for this.
Can I take other medicines with Apixaban?
You should check with your doctor or a pharmacist before taking any other medicines, including those you can buy without a prescription, herbal remedies, or complementary medicines. Some, like aspirin and certain anti-inflammatory painkillers, can interfere with Apixaban.
What should I do if I cannot swallow the Apixaban tablet whole?
If you have difficulty swallowing the tablet whole, you can crush it and mix it with 30 ml (two tablespoons) of water or apple juice. Alternatively, you can mix it with some apple purée. Make sure to swallow the mixture immediately after preparing it.
Vidare läsning och referenser
- Manufacturer's PIL, Eliquis® 2.5 mg film-coated tablets; Bristol-Myers Squibb-Pfizer, The electronic Medicines Compendium. Dated March 2022.
- Manufacturer's PIL, Eliquis® 5 mg film-coated tablets; Bristol-Myers Squibb-Pfizer, The electronic Medicines Compendium. Dated March 2022.
- Mediciner Komplett BNF 89:e Utgåvan; Brittiska Läkarföreningen och Kungliga Farmaceutiska Sällskapet i Storbritannien, London.
Om författarenVisa fullständig biografi

Helen Allen, MPharm
Apotekare, Medicinsk Författare
MPharm
Helen Allen kvalificerade sig som apotekare 1979 och tillbringade 3 år som författare av läkemedelsinformationsbroschyrer för EMIS.
Om recensenten

Sid Dajani
Sultan Dajani tog examen vid London School of Pharmacy 1994 och blev den yngsta valda medlemmen i Royal Pharmaceutical Society-rådet sedan dess grundande 1842.
Artikelhistorik
Informationen på denna sida är skriven och granskad av kvalificerade kliniker.
Artikeln finns också på Engelska, Tyska, Spanska, Franska, Italienska, Portugisiska, Hindi, Hebreiska, Arabiska, och Svenska.
Next review due: 25 Mar 2027
27 Oct 2022 | Senaste versionen
6 Nov 2013 | Ursprungligen publicerad
Författad av:
Helen Allen, MPharm

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