Flucloxacillin for infection
Granskad av Dr Colin Tidy, MRCGPSenast uppdaterad av Michael Stewart, MRPharmSLast updated 27 Apr 2023
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Flucloxacillin is a type of penicillin - ta inte it if you are allergic to penicillin. Make sure you tell your doctor if you are allergic to penicillin.
Take when your stomach is empty. This means you should take your doses an hour before meals or two hours after a meal. Space your doses out evenly over the day and complete the full course of antibiotic.
Common side effects include nausea, vomiting, and diarrhoea.
Om du får en allergisk reaktion (som svullnad runt munnen, andningssvårigheter eller ett rött utslag) kontakta en läkare omedelbart.
I den här artikeln:
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About flucloxacillin
Typ av medicin | Penicillin antibiotic |
Används för | Bacterial infections (adults and children) |
Även kallad | Floxacillin (in US) |
Tillgänglig som | Capsules, oral liquid medicine and injections |
What is flucloxacillin used for?
Tillbaka till innehållFlucloxacillin is a type of penicillin antibiotic used to treat bacterial infections such as öroninfektioner, skin infections, bone infections, and heart and bröstinfektioner. It works by killing the bacteria causing the infection.
Flucloxacillin is also used before some surgical operations to prevent an infection from developing.
Flucloxacillin is available in combination with another antibiotic in a medicine called co-fluampicil. For information on this medicine read our leaflet Co-fluampicil for infection.
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Flucloxacillin side effects
Tillbaka till innehållThe most common side effects of flucloxacillin are:
Känna sig illamående (illamående).
Kräkningar.
Diarré.
Hudutslag.
You will find a full list in the manufacturer's information leaflet supplied with your medicine.
The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
How to manage flucloxacillin side effects
Tillbaka till innehållCommon flucloxacillin side effects - these affect fewer than 1 in 10 people | Vad kan jag göra om jag upplever detta? |
Feeling sick or being sick | Håll dig till enkel mat |
Diarré | Drink plenty of water to replace any lost fluids. If the diarrhoea continues, becomes severe, or contains blood, let your doctor know omedelbart |
Skin rash | Låt din läkare veta så snart som möjligt, eftersom din behandling kan behöva ändras |
Viktigt: if you develop an itchy rash, or a swollen face or mouth, or have difficulty breathing, these may be signs that you are allergic to a penicillin antibiotic.
Do not take any more flucloxacillin and speak with your doctor or go to your local accident and emergency department straightaway.
If you experience any other symptoms which you think may be due to the medicine, speak with your doctor, pharmacist or health professional.
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Who should not take flucloxacillin
Tillbaka till innehållSome medicines are not suitable for people with certain conditions. Before starting flucloxacillin it is important that your doctor or pharmacist knows:
If you are pregnant or breastfeeding. (Although flucloxacillin is not known to be harmful to babies, it is still important that you tell your doctor if you are expecting or breastfeeding a baby.)
If you have problems with the way your liver works.
If you have kidney problems.
Om du tar några andra läkemedel. Detta inkluderar alla läkemedel du tar som finns att köpa utan recept, samt växtbaserade och komplementära läkemedel.
If you have an allergic condition, or if you have ever had an allergic reaction to a medicine. This is particularly important if you have ever had a bad reaction to any penicillin antibiotic.
How to take flucloxacillin
Tillbaka till innehållBefore you start this antibiotic, read the manufacturer's printed information leaflet from inside the pack. The leaflet will give you more information about flucloxacillin and a full list of side effects which you may experience from taking it.
Take your dose of flucloxacillin exactly as your doctor tells you to. It is taken four times a day Your doctor or pharmacist will tell you how many capsules (or how much liquid medicine) to take for each dose, and this information will be printed on the label of the pack to remind you.
Om du har fått flytande medicin för ett barn, läs anvisningarna noggrant för att säkerställa att du mäter upp rätt mängd medicin.
You should take flucloxacillin 'on an empty stomach', which means you should take it about an hour before a meal, for example midday before lunch or in the morning before breakfast, or wait until two hours afterwards.
This is because your body absorbs less flucloxacillin after a meal, which means the medicine is less effective. Space the doses out evenly during the day.
Swallow the capsules whole - do not chew or open them. Some people find it helps to swallow the capsules with a drink of water.
Om du glömmer att ta en dos, ta en så snart du kommer ihåg. Försök att ta rätt antal doser varje dag, men ta inte två doser samtidigt för att kompensera.
Even if you feel your infection has cleared up, keep taking the antibiotic until the course is finished, unless you are told to stop. This is to prevent the infection from coming back.
Your doctor will tell you how long your course of treatment will last. If you still feel unwell after finishing the course, go back to see your doctor.
Få ut det mesta av din behandling
Tillbaka till innehållVissa människor utvecklar svampinfektion (rodnad och klåda i munnen eller slidan) efter att ha tagit en antibiotikakur. Om du tror att du har svampinfektion, prata med din läkare eller apotekare för råd.
If you are using oral combined hormonal contraception (the 'pill'), additional contraceptive precautions such as condoms are recommended for a time if you have sickness (vomiting) or diarrhoea which lasts for more than 24 hours. If you need further advice about this, speak with your doctor or pharmacist.
If you need pain relief whilst taking flucloxacillin it is best to speak to your doctor or a pharmacist first. The painkiller paracetamol is not always recommended during treatment with flucloxacillin, especially if you also have problems with the way your kidneys work.
If you are having an operation or any other medical treatment, tell the person carrying out the treatment that you are taking an antibiotic.
Flucloxacillin may stop the oral typhoid vaccine from working. If you are having any vaccinations, make sure the person treating you knows that you are taking this antibiotic.
If you are taking flucloxacillin over an extended period of time, your doctor will want to routinely check on your progress. Try to keep any regular appointments you have booked with your doctor, as you will need to have some blood tests to check that your liver and kidneys are working well.
How to store flucloxacillin
Tillbaka till innehållFörvara alla läkemedel utom räckhåll och synhåll för barn.
Store flucloxacillin capsules in a cool, dry place, away from direct heat and light.
Om du har fått flytande medicin, förvara den i kylskåp. Den har blandats av apoteket och håller i sju dagar, så kontrollera utgångsdatumet på flaskan och använd den inte efter detta datum.
Viktig information om alla läkemedel
Tillbaka till innehållViktig information om alla läkemedel
Ta aldrig mer än den föreskrivna dosen. Om du misstänker att du eller någon annan kan ha tagit en överdos av denna medicin, gå till akutmottagningen på ditt lokala sjukhus. Ta med behållaren, även om den är tom.
Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.
Om du köper några mediciner, kontrollera med en apotekare att de är säkra att ta tillsammans med dina andra mediciner.
Om du ska genomgå en operation eller någon tandbehandling, informera den som utför behandlingen om vilka mediciner du tar.
Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.
Om du har några frågor om denna medicin, fråga din apotekare.
Rapportera biverkningar av ett läkemedel eller vaccin
Om du upplever biverkningar kan du rapportera dem online via Yellow Card website.
Vanliga frågor
Tillbaka till innehållIs flucloxacillin good for ear infections?
Flucloxacillin is not usually the first choice for most ear infections. It mainly targets bacteria that cause skin and soft tissue infections, rather than the more common bacteria linked to middle ear infections.
Is flucloxacillin stronger than penicillin?
Flucloxacillin and penicillin are not stronger or weaker versions of each other, but different antibiotics used for different types of infections.
Will flucloxacillin affect my contraception?
Flucloxacillin does not affect most forms of contraception, including the combined pill and the progestogen-only pill. However, if the antibiotic causes vomiting or diarrhoea for more than 24 hours, your pill may not be absorbed properly. In that case, follow your pill’s guidance for missed pills and consider using extra protection until you’re well again.
Can I drive on flucloxacillin?
Yes, most people can drive while taking flucloxacillin, as it does not usually cause drowsiness. However, if you feel unwell, dizzy or light-headed from either the medicine or the infection itself, it is safer to avoid driving until you feel better.
Can I drink alcohol on flucloxacillin?
Yes, you can drink alcohol while taking flucloxacillin, as alcohol does not usually interfere with how the medicine works. However, it is best to drink in moderation, as alcohol can make you feel more tired or unwell when you are recovering from an infection
Is there any food or drink I need to avoid when taking flucloxacillin?
No, there are no specific foods or drinks you need to avoid while taking flucloxacillin. However, it is best to take the medicine on an empty stomach, either one hour before or two hours after eating, as food can reduce how well it is absorbed. Drinking plenty of fluids can also help your recovery.

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Vidare läsning och referenser
- Manufacturer's PIL, Flucloxacillin 125 mg/ 5 ml Oral Solution; Aurobindo Pharma - Milpharm Ltd, The electronic Medicines Compendium. Dated February 2022.
- Manufacturer's PIL, Flucloxacillin 250 mg and 500 mg capsules; Aurobindo Pharma - Milpharm Ltd, The electronic Medicines Compendium. Dated January 2021.
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About the authorView full bio

Michael Stewart, MRPharmS
Medicine Leaflet Review Manager – Contractor, Pharmacist
BPharm (Hons), MRPharmS
Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.
About the reviewerView full bio

Dr Colin Tidy, MRCGP
General Practitioner, Medical Author
MBBS, MRCGP, MRCP (Paediatrics), DCH
Dr Colin Tidy is an NHS Doctor, based in Oxfordshire.
Artikelhistorik
Informationen på denna sida är skriven och granskad av kvalificerade kliniker.
Next review due: 26 Oct 2027
27 Apr 2023 | Senaste versionen

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