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Naltrexone tablets

Adepend

Naltrexone will help you to remain free from your dependence on opiate drugs.

It will be prescribed for you by a specialist clinic.

Keep your regular appointments with your doctor. This is so your progress can be checked.

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About naltrexone

Typ av medicin

An opioid antagonist

Används för

To help prevent relapse in people with previous opioid or alcohol dependence

Även kallad

Adepend®

Tillgänglig som

Tabletter

You will have been prescribed naltrexone if you have been through an opiate or alcohol detoxification regime and you are committed to remaining drug/alcohol-free. Alongside other forms of treatment and abstinence support, taking naltrexone can help you to remain free from your dependence.

Naltrexone acts by blocking opioid receptors in your brain and nervous system. This means that you will no longer experience the euphoria-like effects that you previously experienced from substance use. Knowing this will help to support your decisions to stay drug/alcohol-free.

Your treatment with naltrexone will be started and supervised by an appropriate specialist.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking naltrexone it is important that your doctor knows:

  • If you have taken any opiate drug in the previous 10 days. This includes any cough medicines or painkillers that contain opiates.

  • Om du har några problem med hur din lever fungerar, eller om du har några problem med hur dina njurar fungerar.

  • Om du är gravid eller ammar.

  • Om du tar eller använder några andra läkemedel. Detta inkluderar alla läkemedel du tar som finns att köpa utan recept, samt växtbaserade och komplementära läkemedel.

  • Om du någonsin har haft en allergisk reaktion mot en medicin.

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  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about naltrexone and will provide you with a full list of the side-effects which you may experience from taking it.

  • Take naltrexone exactly as your doctor tells you to. Your dose will be printed on the label of the pack to remind you about what was said to you.

  • When starting the treatment, your doctor will give you a small dose of 25 mg a day (half a tablet) and then will increase the dose to one 50 mg tablet a day. The usual maintenance dose is 50 mg (one tablet) each day, although your doctor may suggest that you take naltrexone on three days of the week only (such as two tablets on Mondays and Wednesdays and three tablets on Fridays).

  • Try to take your doses at the same time of day each day, as this will help you to remember to take the tablets regularly. Swallow the tablet with a drink of water. It can be taken either before or after a meal.

  • If you forget to take a dose at your usual time, take it when you remember. If you do not remember until the following day, leave out the forgotten dose but make sure that you remember to take that day's dose. Do not take two doses together to make up for a forgotten dose.

  • Keep your regular appointments with your doctor and programme supervisor. This is so that your progress can be checked. Before you are prescribed naltrexone, your doctor is likely to test you to make sure that you are free from opiates. Also, your doctor will want to take a blood sample from you both before and during your treatment with naltrexone to check that your liver is working well.

  • Keep taking the tablets until your doctor tells you otherwise. You may need to continue to take naltrexone for a number of months, although your doctor will review this regularly.

  • If you are having any medical treatment, you must tell the person carrying out the treatment that you are taking naltrexone. This is particularly important to ensure that you get proper pain treatment in case of an emergency.

  • If you buy any medicines 'over the counter', always check with a pharmacist that they are suitable for you to take with naltrexone. Some medicines for cold and flu symptoms contain weak opioids, as do some medicines for diarrhoea - you must not take these.

  • These tablets are for you - do not give them to anyone else, even if their condition appears to be the same as yours. If they are taken by anyone who is dependent on opioids, they could cause serious life-threatening withdrawal symptoms.

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Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with naltrexone. You will find a full list in the manufacturer's information leaflet supplied with your tablets. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Very common naltrexone side-effects (these affect more than 1 in 10 people)

Vad kan jag göra om jag upplever detta?

Headaches, muscle aches and pains

Ask your clinic to recommend a suitable painkiller

Feeling nervous or restless, lack of energy, difficulties sleeping

If any of these become troublesome, speak with your doctor for advice

Känner dig sjuk (illamående), magont (bukbesvär)

Stick to simple meals - avoid rich and spicy food

Common naltrexone side-effects (these affect fewer than 1 in 10 people)

Diarré

Drick mycket vatten för att ersätta de förlorade vätskorna

Förstoppning

Try to eat a well-balanced diet and drink plenty of water each day

Känner dig yr

If this happens, do not drive and do not use tools or machines

Feeling thirsty, feeling shivery, lack of appetite, watery eyes, skin rash, erectile difficulties, difficulties passing urine, and mood changes

If any of these become troublesome, speak with your doctor for advice

If you experience any other symptoms which you think may be due to the tablets, please speak with your doctor or pharmacist for further advice.

  • Förvara alla läkemedel utom räckhåll och synhåll för barn.

  • Förvara på en sval, torr plats, borta från direkt värme och ljus.

Viktig information om alla läkemedel

Ta aldrig mer än den föreskrivna dosen. Om du misstänker att du eller någon annan kan ha tagit en överdos av denna medicin, gå till akutmottagningen på ditt lokala sjukhus. Ta med behållaren, även om den är tom.

Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.

Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.

Om du har några frågor om denna medicin, fråga din apotekare.

Rapportera biverkningar av ett läkemedel eller vaccin

Om du upplever biverkningar kan du rapportera dem online via Yellow Card website.

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Vidare läsning och referenser

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About the authorView full bio

Author image

Michael Stewart, MRPharmS

Medicine Leaflet Review Manager – Contractor, Pharmacist

BPharm (Hons), MRPharmS

Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.

About the reviewer

Author image

Sid Dajani

Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.

Artikelhistorik

Informationen på denna sida är skriven och granskad av kvalificerade kliniker.

  • Next review due: 23 Jun 2027
  • 16 Jun 2024 | Senaste versionen

    Senast uppdaterad av

    Michael Stewart, MRPharmS

    Granskad av

    Sid Dajani
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