Ranolazin för kärlkramp
Ranexa
Granskad av Sid DajaniSenast uppdaterad av Michael Stewart, MRPharmSSenast uppdaterad 16 jan 2025
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Ranolazine is one of several medicines you will be prescribed for angina.
Take one tablet twice daily.
Do not drink grapefruit juice while you are on ranolazine.
Överblick
Ranolazine is a medicine used to prevent angina chest pain when other medicines are not enough.
It works by improving the blood supply to your heart muscle.
Take one tablet twice a day, exactly as your doctor tells you to.
Do not drink grapefruit juice while taking ranolazine.
It is not for relieving angina attacks; use your prescribed nitrate medicine for that.
Common side-effects include dizziness, headache, constipation, and nausea.
About ranolazine for angina
Typ av medicin | An anti-anginal medicine |
Används för | To prevent angina chest pain |
Även kallad | Ranexa®, Ranogelan®, Anzipro® |
Tillgänglig som | Tabletter |
Angina is a pain that comes from the heart. It is usually caused by the narrowing of one or more of the arteries that supply blood to your heart. This narrowing reduces the blood supply to parts of your heart muscle. When your heart needs more blood and oxygen than it can get through the narrowed arteries (for example, when you walk fast or climb stairs), you feel angina pain.
Ranolazine is taken in addition to other medicines used to prevent angina pain. You will be prescribed it if the other anti-anginal medicines you are taking are not sufficiently controlling your chest pains.
Before taking ranolazine
Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking ranolazine it is important that your doctor knows:
Om du är gravid eller ammar.
If you know you have an irregular heart rhythm.
If you have been told you have heart failure, which is a condition where your heart is not working as well as it should.
If you have any problems with the way your liver works, or any problems with the way your kidneys work.
Om du någonsin har haft en allergisk reaktion mot en medicin.
Om du tar eller använder några andra läkemedel. Detta inkluderar alla läkemedel du tar som finns att köpa utan recept, samt växtbaserade och komplementära läkemedel.
How to take ranolazine
Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about ranolazine and will also provide you with a full list of side-effects which you could experience from taking it.
Take ranolazine exactly as your doctor tells you to. It is usual to take one tablet two times a day. When starting your treatment your doctor will give you a smaller-strength tablet (375 mg tablet) and may then gradually increase your dose to a 500 mg or a 750 mg strength of tablet. This allows your doctor to make sure that you have the dose that helps your condition but avoids any unwanted symptoms.
Try to take your doses at the same times of day each day, as this will help you to remember to take them regularly. You can take ranolazine either before or after a meal. Swallow the tablet whole (without chewing or crushing it) with a drink of water.
If you forget to take a dose at your usual time, take it when you remember. However, if it is nearly time to take your next dose then leave out the forgotten dose and take your next dose when it is due. Do not take two doses together to make up for a missed dose.
Få ut det mesta av din behandling
Ranolazine tablets are not suitable to take to relieve pain if you are having an angina attack. Your doctor will also prescribe a nitrate medicine, such as glyceryl trinitrate (GTN), for you to take if this happens. If after using GTN your pain has not eased within a few minutes, call for an ambulance.
Försök att hålla dina regelbundna möten med din läkare. Detta är så att din läkare kan följa upp din utveckling.
Treatment with ranolazine is usually long-term unless you experience an adverse effect. Continue to take the tablets unless you are advised otherwise by your doctor.
Do not drink grapefruit juice while you are on ranolazine. This is because a chemical in grapefruit juice increases the amount of ranolazine in your bloodstream. This makes side-effects more likely.
It is important if you buy any medicines 'over the counter' to check with a pharmacist that they are suitable for you to take. Some medicines and herbal remedies should not be taken with ranolazine.
Can ranolazine cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with ranolazine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common ranolazine side-effects (these affect fewer than 1 in 10 people) | Vad kan jag göra om jag upplever detta? |
Feeling dizzy or weak | Do not drive and do not use tools or machines while affected. Please let your doctor know about any dizziness as your dose may need adjusting |
Huvudvärk | Drick mycket vatten och be din apotekare rekommendera en lämplig smärtstillande. Om huvudvärken fortsätter, informera din läkare |
Förstoppning | Eat a well-balanced diet and drink plenty of water |
Feeling sick (nausea) or being sick (vomiting) | Eat simple meals - avoid rich or spicy food. If this continues let your doctor know as your dose may need adjusting |
Om du upplever några andra symtom som du tror kan bero på tabletterna, tala med din läkare eller apotekare för vidare råd.
How to store ranolazine
Förvara alla läkemedel utom räckhåll och synhåll för barn.
Förvara på en sval, torr plats, borta från direkt värme och ljus.
Viktig information om alla läkemedel
Viktig information om alla läkemedel
Never take more than the prescribed dose. If you suspect that you or someone else might have taken an overdose of this medicine go to the accident and emergency department of your local hospital at once. Take the container with you, even if it is empty.
Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.
Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.
Om du har några frågor om denna medicin, fråga din apotekare.
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Vanliga frågor
Can I take ranolazine to relieve an angina attack?
No, ranolazine tablets are not suitable for relieving pain during an angina attack. Your doctor will prescribe a different medicine, such as glyceryl trinitrate (GTN), for you to take if you have an attack. If your pain does not ease within a few minutes of using GTN, you should call for an ambulance.
How long will I need to take ranolazine?
Treatment with ranolazine is usually long-term. You should continue to take the tablets unless your doctor advises you otherwise.
What should I do if I feel dizzy while taking ranolazine?
If you feel dizzy or weak, you should not drive or operate tools or machines. It's important to let your doctor know about any dizziness, as your dose may need to be adjusted.
What kind of anti-anginal medicine is ranolazine?
Ranolazine is an anti-anginal medicine prescribed to prevent angina chest pain. It is taken in addition to other medicines for angina, typically when those other medicines are not fully controlling your chest pain.
Can I take over-the-counter medicines or herbal remedies with ranolazine?
If you buy any medicines over the counter, including herbal and complementary medicines, it's important to check with a pharmacist that they are suitable for you to take. Some medicines and herbal remedies should not be taken together with ranolazine.
Vidare läsning och referenser
- Manufacturer's PIL, Ranexa® 375 mg, 500 mg and 750 mg prolonged-release tablets; A. Menarini Farmaceutica Internazionale SRL, The electronic Medicines Compendium. Dated January 2021.
- Mediciner Komplett BNF 89:e Utgåvan; Brittiska Läkarföreningen och Kungliga Farmaceutiska Sällskapet i Storbritannien, London.
Om författarenVisa fullständig biografi

Michael Stewart, MRPharmS
Ansvarig för granskning av medicinbroschyrer – Konsult, Apotekare
BPharm (Hons), MRPharmS
Michael är en apotekare som arbetar i Midlands och South Yorkshire med mer än 20 års erfarenhet av att ge råd om läkemedel och medicinska tillstånd. Han har en stark bakgrund inom vårdutbildning och har producerat och levererat utbildningskurser för apoteksteam och personal inom vårdboenden, inklusive sjuksköterskor. Han har också bidragit till apoteksrådgivande styrelser för hantering av mindre allvarliga tillstånd i samhället.
Om recensenten

Sid Dajani
Sultan Dajani tog examen vid London School of Pharmacy 1994 och blev den yngsta valda medlemmen i Royal Pharmaceutical Society-rådet sedan dess grundande 1842.
Artikelhistorik
Informationen på denna sida är skriven och granskad av kvalificerade kliniker.
Artikeln finns också på Engelska, Tyska, Spanska, Franska, Italienska, Portugisiska, Hindi, Hebreiska, Arabiska, och Svenska.
Next review due: 16 Jan 2028
16 jan 2025 | Senaste versionen

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