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Acenokumarol - ett antikoagulant

Sinthrome

Acenocoumarol is an anticoagulant. It will be prescribed if you have an unwanted clot in your blood, or if you are at risk of having an unwanted clot.

You may be given a yellow booklet about your anticoagulant treatment; read this carefully.

You will need to have regular blood tests to measure how quickly your blood clots.

What you eat and drink can affect your treatment. Do not change your diet without discussing it with your doctor first. Do not drink cranberry juice.

Överblick

  • Acenocoumarol is an anticoagulant medicine that helps prevent harmful blood clots.

  • It works by reducing the effects of vitamin K, which is used to make blood-clotting factors.

  • You will need regular blood tests to check how quickly your blood clots.

  • Avoid cranberry juice and discuss dietary changes or other medicines with your doctor.

  • The most common side effects are unusual bleeding or bruising.

  • See your doctor straight away if you have unusual bleeding or a skin rash.

About acenocoumarol

Typ av medicin

An anticoagulant

Används för

Prevention and treatment of harmful blood clots

Även kallad

Sinthrome®

Tillgänglig som

Tabletter

Acenocoumarol is an anticoagulant medicine, which means that it increases the time it takes for your blood to clot. It works by reducing the effects of vitamin K, which is a vitamin your body uses to make blood-clotting factors.

Acenocoumarol is prescribed to prevent unwanted clots from forming if you have a condition that puts you at risk of this happening, such as förmaksflimmer, or if you have had a heart valve replacement. It is also given to prevent any clots that may have already formed in the blood vessels of your legs, lungs or heart from becoming larger and causing problems. Another anticoagulant, called warfarin, is usually prescribed in preference to acenocoumarol. However, if warfarin is not suitable for you, you may be prescribed acenocoumarol instead.

Before taking acenocoumarol

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking acenocoumarol it is important that your doctor knows:

  • Om du är gravid, försöker bli gravid eller ammar.

  • If you have any cuts or wounds.

  • If you have a condition that increases your risk of bleeding, such as a stomach ulcer, or if you have had surgery recently, or if you have recently had a stroke.

  • If you have any problems with the way your liver works, or with the way your kidneys work.

  • Om du har högt blodtryck.

  • If you have been told you have an infection of your heart, called bacterial endocarditis.

  • Om du tar eller använder några andra läkemedel. Detta inkluderar alla läkemedel du tar som finns att köpa utan recept, samt växtbaserade och komplementära läkemedel.

  • Om du någonsin har haft en allergisk reaktion mot en medicin.

How to take acenocoumarol

  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack of tablets and any additional information you have been given by your doctor. These will give you more information about acenocoumarol and will provide you with a full list of the side-effects which you may experience from taking it.

  • Take acenocoumarol once a day, exactly as you have been advised by your doctor or anticoagulant clinic. You should aim to take acenocoumarol at the same time each day. This will help keep the levels of the medicine in your blood steady and will also help you to avoid missing any doses. Your doctor will tell you how many tablets to take for each dose. Swallow the tablet(s) whole with a drink of water.

  • If you forget to take a dose at your usual time, take it as soon as you remember if it is still the same day. If you do not remember until the following day, do not take the missed dose but do remember to take the dose that is due on that day. Remember to let your doctor know about any missed doses when you next have your blood test.

  • Continue to take acenocoumarol tablets regularly until your doctor tells you to stop. A course of treatment typically lasts from six weeks to three months, although some people may be advised to continue taking the tablets long-term.

Få ut det mesta av din behandling

  • You will be given a yellow 'Oral Anticoagulant Therapy' booklet; please read this carefully as it gives you important information such as when you should contact a doctor for advice. You will also be given an 'Anticoagulant Alert Card' which you should carry with you at all times. In case of an emergency, a doctor will need to know that you are taking acenocoumarol.

  • You will need to have regular blood tests to check on how quickly your blood clots. Blood tests may be needed quite often at first but should reduce in frequency quite quickly. The extent to which acenocoumarol is working is measured by the International Normalised Ratio (INR), which is a measure of the ability of your blood to prevent clotting. The amount of acenocoumarol that you need to take will depend upon the result of these blood tests and this is why your dose may change from time to time. The aim is to get the dose of acenocoumarol just right so your blood does not clot as easily as normal but not so much as to cause bleeding problems.

  • Changing your diet suddenly can affect your INR, especially if you begin to eat more vegetables and salad than before. You should not begin a weight-reducing diet without discussing it with your doctor first. A major change in diet will mean that you need closer monitoring as your dose may need to be adjusted.

  • Only drink alcohol in small amounts, as this can affect the levels of the medicine in your body. Limit the amount of alcohol that you drink to a maximum of one or two units in any day and never binge drink.

  • Drinking cranberry juice can interfere with acenocoumarol and affect your INR, so it is best if you avoid cranberry juice and other cranberry products altogether.

  • If you buy any medicines, check with a pharmacist that they are safe to take with acenocoumarol. For example, you should not take some painkillers (such as aspirin and other anti-inflammatory painkillers) and some vitamin and herbal preparations. If you need to take a painkiller, you may take paracetamol but you should let your doctor know if you need to take it regularly.

  • Because acenocoumarol is used to prevent blood clots from forming, you should try to avoid activities that could cause you to cut or bruise yourself, such as contact sports. Let your doctor know if you have any falls or injuries.

  • You should avoid getting pregnant while you are taking acenocoumarol as it may cause harm to an unborn baby. Make sure you have discussed with your doctor which types of contraception are suitable for you and your partner.

  • If you are due to have any injections, or any medical or dental treatment, please tell the person carrying out the treatment that you are taking an anticoagulant and show them your treatment booklet. It is important that they know you may take longer to stop bleeding. If you are due to have surgery, you may be advised to stop taking acenocoumarol for a few days and be given injections instead.

Can acenocoumarol cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the side-effects associated with acenocoumarol - the most common ones are bleeding and bruising. You will find a full list in the manufacturer's information leaflet supplied with your medicine. Speak with your doctor or pharmacist if any of the following continue or become troublesome.

Common acenocoumarol side-effects

Vad kan jag göra om jag upplever detta?

Unusual bleeding or bruising, blood in your urine or stools

See your doctor straightaway - your dose will probably need to be reduced

Rare acenocoumarol side-effects (these affect fewer than 1 in 10,000 people)

Vad kan jag göra om jag upplever detta?

Känna sig illamående (nausea) eller kräkas (vomiting), aptitlöshet

Let your doctor know if this continues

Loss of hair

If this becomes troublesome, speak with your doctor

Skin rash

See your doctor straightaway - this could be a sign of an allergic reaction to acenocoumarol

Om du upplever några andra symtom som du tror kan bero på tabletterna, tala med din läkare eller apotekare för vidare råd.

How to store acenocoumarol

  • Förvara alla läkemedel utom räckhåll och synhåll för barn.

  • Förvara på en sval, torr plats, borta från direkt värme och ljus.

Viktig information om alla läkemedel

Viktig information om alla läkemedel

Ta aldrig mer än den föreskrivna dosen. Om du misstänker att du eller någon annan kan ha tagit en överdos av denna medicin, gå till akutmottagningen på ditt lokala sjukhus. Ta med behållaren, även om den är tom.

Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.

Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.

Om du har några frågor om denna medicin, fråga din apotekare.

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Vanliga frågor

What is the typical duration of acenocoumarol treatment?

The duration of treatment can vary. It typically lasts from six weeks to three months, but some individuals may be advised to continue taking the tablets long-term, depending on their specific medical condition.

How does alcohol consumption affect acenocoumarol?

Drinking alcohol can interfere with the levels of acenocoumarol in your body, potentially impacting its effectiveness. It's recommended to limit alcohol intake to a maximum of one to two units per day and to avoid binge drinking.

Are there any specific situations when I should immediately tell my doctor about taking acenocoumarol?

Yes, you should always inform any medical or dental professional, or anyone giving you injections, that you are taking an anticoagulant. This is crucial because it can affect how long it takes for your blood to clot, which is important information for their procedures. In an emergency, your 'Anticoagulant Alert Card' will also inform doctors.

What should I do if I notice unusual bleeding or bruising while taking acenocoumarol?

If you experience unusual bleeding or bruising, or notice blood in your urine or stools, you should see your doctor straight away. These can be signs that your dose needs to be adjusted.

Why is acenocoumarol preferred over warfarin in some cases?

While warfarin is generally the first choice, acenocoumarol may be prescribed if warfarin is not suitable for you. The article does not specify the exact reasons for this unsuitability, but it indicates it's an alternative option.

Should I be concerned about hair loss when taking acenocoumarol?

Hair loss is listed as a rare side effect of acenocoumarol, affecting fewer than 1 in 10,000 people. If this becomes troublesome for you, you should speak with your doctor.

Vidare läsning och referenser

Om författarenVisa fullständig biografi

Författarbild

Michael Stewart, MRPharmS

Ansvarig för granskning av medicinbroschyrer – Konsult, Apotekare

BPharm (Hons), MRPharmS

Michael är en apotekare som arbetar i Midlands och South Yorkshire med mer än 20 års erfarenhet av att ge råd om läkemedel och medicinska tillstånd. Han har en stark bakgrund inom vårdutbildning och har producerat och levererat utbildningskurser för apoteksteam och personal inom vårdboenden, inklusive sjuksköterskor. Han har också bidragit till apoteksrådgivande styrelser för hantering av mindre allvarliga tillstånd i samhället.

Om recensenten

Författarbild

Sid Dajani

Sultan Dajani tog examen vid London School of Pharmacy 1994 och blev den yngsta valda medlemmen i Royal Pharmaceutical Society-rådet sedan dess grundande 1842.

Artikelhistorik

Informationen på denna sida är skriven och granskad av kvalificerade kliniker.

  • Next review due: 27 Jul 2027
  • 21 Jul 2024 | Senaste versionen

    Senast uppdaterad av

    Michael Stewart, MRPharmS

    Granskad av

    Sid Dajani
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