Vad orsakar plötslig eksem hos vuxna?

What is eczema and what causes it?

Eksem is a non-contagious, inflammatory skin condition. The most common form, atopic eczema, affects one in five children and one in 10 adults in the UK¹. It causes the skin to become itchy, dry and cracked and can be painful and uncomfortable. Alongside the physical symptoms, a flare-up of eczema can lead to a whole host of other problems too, including sömnlöshet, ångest och depression.

Atopic eczema is often caused by a combination of things, including genetics. You may be born with a higher chance of developing eczema if other family members have the condition. Being prone to eksem may make your skin more likely to react to certain triggers, such as cold weather, skin products, foods and hormonal changes, among others.

Dr Derrick Phillips, a consultant dermatologist and British Skin Foundation spokesperson, says it isn’t always possible to identify a trigger for a sudden flare-up of eczema, which can appear unexpectedly. "However, stress, infections, sweating, changes in the weather, chemicals - such as chlorine - and allergier can all aggravate eczema," he says.

Stress and eczema

When we get stressed, our body has a physiological reaction called the 'fight or flight' response. This was originally a survival mechanism triggered when we faced a life-threatening situation such as a predator, but now, the same response is activated by everyday stresses like work.

During this response, stress hormones like cortisol are released which allow us to react quickly. However, if you are frequently stressed, or feel stressed for long periods of time, cortisol suppresses the immune system and increases inflammation throughout the body - which can trigger or worsen eczema².

Environmental triggers

Environmental factors or allergens such as cold and dry weather, strong sunlight, and dampness can also trigger an eczema flare-up or make symptoms worse. Sometimes, a sudden eczema flare-up can occur if you’ve been exposed to certain allergens, such as dust mites, pet hair, pollen or mould.

Hormones and eczema

Research suggests hormones affect a type of immune cell called Th2, which has been linked to eczema³. Hormones, including oestrogen, progesterone and testosterone can interact with this cell. Therefore, as your levels of these hormones change - for example, in graviditeten or during your period - you may experience changes in eczema symptoms.

Chemicals

Even if you’re careful about what you use on your skin, certain chemicals - including in cosmetics and personal care products - can trigger eczema. Air pollutants are also known to worsen eczema symptoms. These can be found in areas of traffic or from heating systems in buildings, which can make them difficult to avoid⁴.

What are the treatment options for eczema?

"If you experience a sudden flare of adult eczema, arrange to see your doctor or dermatologist," says Phillips. "You may require treatment with topical steroids, which come in different strengths according to the severity of the flare and where it is on the body. In general, steroid ointments are more potent than steroid creams or lotions. They work by soothing the hud, calming inflammation and reducing the itch," he says.

"For sensitive areas such as the face, steroid-sparing creams are recommended - topical medicines which contain fewer side effects than steroid creams. These treatments provide the benefits of steroids without side effects such as thinning of the skin."

Mild flares of eksem may be managed with moisturisers and soap substitutes alone, Phillips says. "While the skin is inflamed, avoid potentially irritating preparations, and opt for products that are fragrance and preservative free," he adds.

Moisturisers also play a key role in managing eczema. "I recommend using ointments at night. They are greasy and may be cosmetically unacceptable for daytime use - as they can feel uncomfortable and stick to clothing, but they are extremely effective at repairing the skincare barrier and locking in moisture overnight. I recommend creams for daytime use. They have a higher water content and are more rapidly absorbed, requiring several applications throughout the day."

For recurrent flares of eczema, Phillips says treatments such as light therapy - the use of ultraviolet light - may be recommended. UV light appears to reduce the number of cells involved in the inflammatory response, which plays an important role in eczema. Reducing the number of these cells may improve symptoms of eksem. This is not the UV light found in sunbeds - which are still not recommended for their higher skin cancer risk, but the treatment offered by specialist hospitals with more controlled UV light.

Antibiotics may be required if there are signs of infection, such as a gold crust, redness, or yellow fluid around the affected area. If the skin is infected, it may also be hot and sore. If you feel your eczema is infected - you must be seen by a doctor.

Vidare läsning

1. National Eczema Society: Our skin and eczema.

2. Mizawa et al: Stress evaluation in adult patients with atopic dermatitis using salivary cortisol.

3. Moreno et al: Targeting the T helper 2 inflammatory axis in atopic dermatitis.

4. Kim: Influences of environmental chemicals on atopic dermatitis.