Sjukt sinus-syndrom
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Sick sinus syndrome (also known as sinus node dysfunction) is a group of related heart conditions that can affect how the heart beats. "Sick sinus" refers to the sino-atrial (SA) node, which is an area of specialized cells in the heart that functions as a natural pacemaker. The SA node generates electrical impulses that start each heartbeat. These signals travel from the SA node to the rest of the heart, signaling the heart (cardiac) muscle to contract and pump blood. In people with sick sinus syndrome, the SA node does not function normally. In some cases, it does not produce the right signals to trigger a regular heartbeat. In others, abnormalities disrupt the electrical impulses and prevent them from reaching the rest of the heart.
Beskrivning
Sick sinus syndrome (also known as sinus node dysfunction) is a group of related heart conditions that can affect how the heart beats. "Sick sinus" refers to the sino-atrial (SA) node, which is an area of specialized cells in the heart that functions as a natural pacemaker. The SA node generates electrical impulses that start each heartbeat. These signals travel from the SA node to the rest of the heart, signaling the heart (cardiac) muscle to contract and pump blood. In people with sick sinus syndrome, the SA node does not function normally. In some cases, it does not produce the right signals to trigger a regular heartbeat. In others, abnormalities disrupt the electrical impulses and prevent them from reaching the rest of the heart.
Sick sinus syndrome tends to cause the heartbeat to be too slow (bradycardia), although occasionally the heartbeat is too fast (tachycardia). In some cases, the heartbeat rapidly switches from being too fast to being too slow, a condition known as tachycardia-bradycardia syndrome. Symptoms related to abnormal heartbeats can include dizziness, light-headedness, fainting (syncope), a sensation of fluttering or pounding in the chest (palpitations), and confusion or memory problems. During exercise, many affected individuals experience chest pain, difficulty breathing, or excessive tiredness (fatigue). Once symptoms of sick sinus syndrome appear, they usually worsen with time. However, some people with the condition never experience any related health problems.
Sick sinus syndrome occurs most commonly in older adults, although it can be diagnosed in people of any age. The condition increases the risk of several life-threatening problems involving the heart and blood vessels. These include a heart rhythm abnormality called atrial fibrillation, heart failure, cardiac arrest, and stroke.
Inheritance patterns
The source lists the following possible inheritance patterns: Autosomal recessive; Autosomal dominant. More than one pattern can apply in different cases.
Related genes
Other names
Sinus node disease
Sinus node dysfunction
SND
SSS
Related patient information and medicines
Patient information leaflet
Akut bihåleinflammation
Sinusitis - also known as a sinus infection - is the swelling of the sinuses, often caused by viral or bacterial infections. Most cases are mild and get better within a few weeks, but chronic sinusitis may require medical treatment. This leaflet explains the symptoms, causes, treatment, and prevention of acute sinusitis. What is sinusitis. Viral.
Patient information leaflet
Nästäppa
Nasal congestion is a blocked, stuffy or bunged-up feeling in the nose. This leaflet deals with the causes and treatment of nasal congestion. What is nasal congestion. Nasal congestion is a bloc... There may be other symptoms along with the blocked nose. What causes nasal congestion. The most common causes of nasal congestion are: Infections: the.
Patient information leaflet
Kronisk bihåleinflammation
Kronisk bihåleinflammation is inflammation of the sinuses that lasts a long time, usually defined as 12 weeks or more. It is less common than acute sinusitis, but appears to be getting more common in all age groups. Surgery to improve the drainage of the sinus is an option if other treatments fail, and usually works well. What is chronic sinusitis..
Patient information leaflet
Näspolyper
Näspolyper är fleshy swellings that grow inside the nose eller sinuses. They are usually non-cancerous (benign). The most common symptoms they cause are a stuffy, runny nose. T... The lining of your sinuses is the same as the lining of your nose, so this is why nasal polyps can also form in your sinuses. The medical name for the inflammation of.
Patient information leaflet
Pilonidalsinus
A pilonidal sinus is an infected tract under the skin between the buttocks. Treatment commonly involves an operation. After the operation it is advised that the area should be kept the area free of growing hair... (A similar condition can occur between the fingers of hairdressers which is caused by customers' hairs entering moist, damaged skin.)..
Patient information leaflet
Bestående rinit
Anti. They are also usually given to small children instead of a nasal spray. How long is treatment needed for. Bestående rinit is an ongoing (chronic) condition that usually needs regular behandling to prevent symptoms. However, over time the condition may ease and even go completely in some cases. Are there any complications of persistent.
Vidare läsning och referenser
- Sjukt sinus-syndrom; MedlinePlus, National Library of Medicine.
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- Dobrzynski H, Boyett MR, Anderson RH. New insights into pacemaker activity: promoting understanding of sick sinus syndrome. Circulation. 2007 Apr 10;115(14):1921-32. doi: 10.1161/CIRCULATIONAHA.106.616011. No abstract available.
- Holm H, Gudbjartsson DF, Sulem P, Masson G, Helgadottir HT, Zanon C, Magnusson OT, Helgason A, Saemundsdottir J, Gylfason A, Stefansdottir H, Gretarsdottir S, Matthiasson SE, Thorgeirsson GM, Jonasdottir A, Sigurdsson A, Stefansson H, Werge T, Rafnar T, Kiemeney LA, Parvez B, Muhammad R, Roden DM, Darbar D, Thorleifsson G, Walters GB, Kong A, Thorsteinsdottir U, Arnar DO, Stefansson K. A rare variant in MYH6 is associated with high risk of sick sinus syndrome. Nat Genet. 2011 Mar 6;43(4):316-20. doi: 10.1038/ng.781.
- Lei M, Huang CL, Zhang Y. Genetic Na+ channelopathies and sinus node dysfunction. Prog Biophys Mol Biol. 2008 Oct-Nov;98(2-3):171-8. doi: 10.1016/j.pbiomolbio.2008.10.003. Epub 2008 Nov 5.
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Artikelhistorik
Artikeln finns också på Engelska, Tyska, Spanska, Franska, Italienska, Portugisiska, Hindi, Hebreiska, Arabiska, och Svenska.
18 aug 2020 | Senaste versionen
1 Aug 2013 | Ursprungligen publicerad
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