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Can I take Ibuprofen and Naproxen together?

Guide för läkemedelsinteraktioner

Taking ibuprofen and naproxen together significantly increases your risk of serious side effects, particularly stomach ulcers, internal bleeding, and kidney problems. It can also make your blood pressure rise and cause fluid retention.

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Do not take ibuprofen och naproxen at the same time. If one is not managing your pain, speak to a pharmacist or doctor about adding a different type of painkiller, such as paracetamol, which works differently and is generally safe to take alongside one NSAID.

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Varför detta händer

Both ibuprofen and naproxen belong to the same family of medicines called NSAIDs (Non-Steroidal Anti-Inflammatory Drugs). They work by blocking the same enzymes in the body.

Taking both is like taking a double dose of the same type of medicine; it doesn't provide better pain relief but it does double the strain on your stomach lining and kidneys.

You may be experiencing an interaction between ibuprofen and naproxen if:

  • You took ibuprofen and naproxen together or close in time.

  • You have black, tarry, or bloody poo (stools).

  • You have stomach pain, heartburn, or feeling sick (nausea).

  • You feel dizzy or very tired.

  • You notice swelling, shortness of breath, or chest pain,

  • You pee less than usual or have swollen ankles/legs.

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If you have any of the above symptoms, you should:

  • Stop taking ibuprofen and naproxen (don’t mix them).

  • Use paracetamol instead for pain, unless a doctor says otherwise.

  • Get urgent help for chest pain, breathing problems, severe stomach pain, or vomiting blood/black stools.

  • Contact a GP or pharmacist if symptoms are mild but don’t go away.

  • Drink water and avoid alcohol while you recover.

Astma

Do not take these medicines if you have asthma, as they can trigger a severe or life-threatening asthma attack (bronchospasm).

Stomach ulcers or bleeding

Avoid these medicines if you have ever had a stomach ulcer or gastrointestinal bleeding, as they significantly increase the risk of serious internal bleeding and perforation.

Pregnancy (third trimester)

Do not take these medicines if you are more than 28 weeks pregnant, as they can cause serious heart and kidney problems in the unborn baby and complications during birth.

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Alkohol

Drinking alcohol while taking NSAIDs like ibuprofen or naproxen can increase the risk of stomach irritation, stomach ulcers, and gastrointestinal bleeding. It is best to limit alcohol intake or avoid it entirely if you have a history of stomach issues.

Food (General)

While not an interaction that changes how the drug works, you should ideally take these medicines with or just after food or a snack. This helps to protect your stomach lining and reduces the risk of indigestion or stomach pain.

Taking multiple medicines? Our Interaktionskontroll för läkemedel helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Ansvarsfriskrivning

Denna information är endast avsedd för allmän utbildning och bör inte användas som en ersättning för professionell medicinsk rådgivning. Rådfråga alltid din läkare, apotekare eller annan kvalificerad vårdpersonal innan du fattar beslut om dina mediciner. Individuella omständigheter kan variera, och endast en vårdpersonal som känner till din medicinska historia kan ge personlig vägledning.

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Artikelhistorik

Informationen på denna sida är skriven och granskad av kvalificerade kliniker.

  • 24 jan 2026 | Ursprungligen publicerad
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